A5100393276- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Actinomycetales infections and treatment
- Fungal Infections and Studies
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Pneumonia and Respiratory Infections
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Mycobacterium research and diagnosis
- Cardiac Arrhythmias and Treatments
- Liver Disease Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Nosocomial Infections in ICU
- Antimicrobial Resistance in Staphylococcus
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Viral gastroenteritis research and epidemiology
- Heart Failure Treatment and Management
- Galectins and Cancer Biology
- Nutritional Studies and Diet
- Antibiotics Pharmacokinetics and Efficacy
- HER2/EGFR in Cancer Research
- Adrenal Hormones and Disorders
Nanjing University
2022-2024
Nanjing General Hospital of Nanjing Military Command
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Henan University Huaihe Hospital and Huaihe Clinical Institute
2015-2024
Capital Medical University
2019-2024
Beijing Children’s Hospital
2024
Southern Medical University
2023
Central South University
2013-2023
Chengdu Medical College
2022-2023
Xiangya Hospital Central South University
2013-2023
To survey the difference of frailty prevalence in elderly inpatients amongdifferent wards; to compare diagnostic performance five measurements (Clinical Frailty Scale [CFS], FRAIL, Fried, Edmonton, Index [FI]) identifying frailty; and explore risk factors inpatients.This was a cross-sectional study including 1000 (mean age 75.2±6.7 years, 51.5% male; 542, 229, 229 patients from cardiology, non-surgical, surgical wards, respectively) tertiary hospital September 2018 February 2019. We applied...
Introduction: As the third generation of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), osimertinib has demonstrated more significant cardiotoxicity than previous generations EGFR-TKIs. Investigating mechanism can provide a reference for comprehensive understanding osimertinib-induced and safety usage this drug in clinical practice. Methods: Multichannel electrical mapping with synchronous ECG recording was used to investigate effects varying concentrations on...
Abstract Background The difference in the long-term outcomes of myocardial infarction patients with non-obstructed coronary arteries (MINOCA) and obstructed artery disease (MI-CAD) is not clear. current study aimed to pool adjusted data compare MINOCA vs MI-CAD. Methods Electronic literature search PubMed, Embase, CENTRAL, Google Scholar databases was done for publications up 18th June 2023. Only studies reporting multivariable-adjusted > 1 year follow-up were included. Results Sixteen...
Objective The aim of this study was to determine the serum levels visfatin, adiponectin, and insulin resistance (IR) in patients with hepatitis C virus (HCV) infection their relations biochemical markers C. Materials methods This carried out on 40 HCV-infected sex/age/BMI-matched healthy adults. Lipid profile, liver function tests, IR, visfatin all were examined. Correlations between other variables analyzed. Results adiponectin significantly lower HCV compared controls. However, IR higher...
BACKGROUND:There is a growing recognition of sex-related disparities in atrial fibrillation (AF). However, limited data available Chinese AF patients. MATERIAL AND METHODS:We compared symptoms, quality life (QoL), and treatment according to sex from the China Registry study. RESULTS:We studied 14 723 patients with non-valvular AF, whom 5645 (38.3%) were female. Women older than men (67.5±10.6 vs. 62.2±12.2). Compared men, women had more comorbidities higher proportion CHA₂DS₂-VASC score ≥2....
Elevated serum uric acid is commonly associated with high triglyceride. However, the relation of triglyceride and hyperuricemia in different gender age groups currently not well understood. This study aimed to evaluate age- gender-related association a subgroup Chinese population.We retrospectively analyzed physical examination data 24,438 subjects (12,557 men 11,881 women) Kaifeng, China. The alanine aminotransferase, γ-glutamyl transpeptidase, creatinine, blood urea nitrogen, total...
This study aimed to investigate the erythrocyte sedimentation rate (ESR) optimal cutoff point in Chinese patients with diabetic foot osteomyelitis (DFO) and evaluate screening value of ESR combined probe-to-bone (PTB) test for a fast diagnosis DFO early stage. A total 204 inpatients infection were tested white blood cell count, neutrophil %, C reactive protein, at admission within 24 hours. All performed PTB test. Patients (111) confirmed by bone biopsy, other (86) had only soft tissue...
Whilst persistent or recurrent COVID-19 infection is well described among some immunosuppressed patient cohort, to date there have been no reports of this phenomenon in the context repeatedly negative SARS-CoV-2 testing upper respiratory tract. We reported 6 follicular lymphoma developed symptomatic infection. They tested persistently for on pharyngeal swabs and ultimately confirmed by BALF metagenomics next generation sequencing. All patients presented with lymphopenia B-cell depletion, 5...
Abstract Background Vancomycin-associated acute kidney injury (VA-AKI) is the most clinically relevant side effect of vancomycin. The objective this study was to investigate association between VTC and VA-AKI as well 30-day mortality in critically ill elderly adults. Method Elderly patients with trough serum vancomycin concentration records(VTC) Medical Information Mart-IV (MIMIC-IV) eICU databases were retrospectively studied. Results A total 3,146 adults finally enrolled. incidence...
Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, successful treatment remains a mainly clinical challenge, it imperative to develop therapeutic agents.The anti-proliferative effect of ivermectin on ESCC investigated model and nude mice model. Cell apoptosis was assessed using flow cytometry, TUNEL assay western blotting. Mitochondrial dysfunction determined by reactive oxygen species accumulation,...
Hand, Foot, and Mouth Disease (HFMD) is most frequently caused by Enterovirus71 (EV-A71) or Coxsackie virus A16 (CV-A16), infants young children are at greatest risk. Describing the epidemiology of HFMD can help develop better target interventions, including use pediatric EV-A71 vaccination. We obtained data from national surveillance system for cases with onset dates 2009 to 2015. defined probable as patient skin papular vesicular rashes on hands, feet, mouth, buttocks confirmed patients...
Left bundle branch pacing (LBBP) is emerging as an effective alternative to achieve cardiac resynchronization therapy (CRT) and improve heart function. The purpose of our study was investigate the feasibility efficacy LBBP in failure patients with left ventricular ejection fraction (LVEF) <50% block (LBBB).All complete LBBB LVEF were retrospectively included from April 2018 2021 underwent CRT via implantation. ECG, parameters, New York Heart Association (NYHA) functional class,...
The aim of this study was to investigate the effect different routes tirofiban injection on function left ventricle and prognosis patients with myocardial infarction (MI) treated percutaneous coronary intervention (PCI). Ninety‑five MI PCI were divided into two groups [coronary (n=49) intravenous (n=46)] according route. A comparison ventricular made between following PCI. success rate in group 97.96%, which higher than that (P<0.05). No significant differences identified platelet count...
Ischemic post-conditioning (PostC) has been demonstrated as a novel strategy to harness nature's protection against myocardial ischemia-reperfusion (I/R). Hypercholesterolemia (HC) reported block the effect of PostC on heart. Angiotensin II type-1 (AT1) modulators have shown benefits in ischemia. The present study investigates inhibitor AT1, azilsartan heart normocholesterolemic (NC) and HC rats.HC was induced by administration high-fat diet animals for eight weeks. Isolated Langendorff's...
Insulin resistance is a phenomenon in which the lowering blood glucose capacity of insulin decreased, feature type 2 diabetes mellitus. Some previous studies have found an association between and migraine. The triglyceride (TyG) index used to assess resistance. However, there no report on TyG migraine.We present cross-sectional study from National Health Nutrition Examination Survey (NHANES) clarify migraine.Data was acquired NHANES. Migraine diagnosed based patient selfreport prescription...
Abstract Cushing's syndrome is a rare cause of myocardial infarction and heart failure. Herein, we report female patient who presented acute failure with reduced ejection fraction. The was found to have hypercortisolism secondary adrenocortical adenoma responded well therapy. This case underlines the effects on cardiovascular system. clinical presentation this unique because non‐atherosclerotic rarely reported in patients.