A5038971816- Child and Adolescent Psychosocial and Emotional Development
- RNA and protein synthesis mechanisms
- Genomic variations and chromosomal abnormalities
- Glycosylation and Glycoproteins Research
- Autism Spectrum Disorder Research
- Impact of Technology on Adolescents
- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- Child and Animal Learning Development
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Microtubule and mitosis dynamics
- Genetic Associations and Epidemiology
- Bullying, Victimization, and Aggression
- Protein Kinase Regulation and GTPase Signaling
- RNA modifications and cancer
- Gene expression and cancer classification
- Attachment and Relationship Dynamics
- Child Development and Digital Technology
- Media Influence and Health
- Genetics and Neurodevelopmental Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Enzyme Production and Characterization
- Genomics and Rare Diseases
- Immune Cell Function and Interaction
Aalborg University
2019-2023
Aalborg Portland (Denmark)
2020
Institut für Medien- und Kommunikationspolitik
2019
University of Vermont
2012-2018
University of Vermont Medical Center
2012-2018
University of Copenhagen
2010-2017
Tufts University
2016
Tilburg University
2016
National Institute of Mental Health
2013-2014
National Institutes of Health
2009-2014
The distribution and subcellular localization of tubulin MAP2 in brain tissue were analyzed by immunocytochemistry with monoclonal hybridoma antibodies prepared against Chinese hamster MAP2. We examined three anti-tubulin (Tu3B, Tu9B, Tu12) specific for beta-tubulin, two anti-MAP2 (AP9,AP13). specificity each the was characterized staining nitrocellulose electrophoretic blots SDS-polyacrylamide gels whole or hippocampal extracts. Each antibody bound only its respective antigen these...
We have examined the distribution of microtubule-associated protein 2 (MAP2) in lumbar segment spinal cord, ventral and dorsal roots, root ganglia control beta,beta'-iminodipropionitrile-treated rats. The peroxidase-antiperoxidase technique was used for light electron microscopic immunohistochemical studies with two monoclonal antibodies directed against different epitopes Chinese hamster brain MAP2, designated AP9 AP13. MAP2 immunoreactivity present axons motor neurons, but not detected...
The phenomenon of imaginary companions (ICs) has received little attention in developmental psychology, even though it can be observed approximately 25% preschool-aged children. Only a few studies have investigated the effect ICs on children's theory mind and emotion understanding, results are partial or inconsistent. This study used comprehensive measures to assess emotional understanding children aged four six with (N = 24) compared their performance that without 24). Results showed ICs,...
Chronic inflammation is a well-known corollary of the aging process and believed to significantly contribute morbidity mortality many age-associated chronic diseases. However, mechanisms that cause inflammatory changes are not well understood. Particularly, contribution cell stress responses in 'non-inflammatory' cells remains poorly defined. The present cross-sectional study focused on differences molecular signatures indicative states associated with biological human fibroblasts from...
This study investigated children's ability to understand false beliefs and the emotions caused by with a special focus on understanding of their own belief-based emotions. Forty-five children (25 boys 20 girls) between ages 5 7 years were tested for of: (1) belief self other; (2) emotion other. Testing procedures included variation classic "Smarties" task (Hogrefe, Wimmer, & Perner, 1986 Hogrefe, G.-J., H. J. 1986. Ignorance versus belief: A developmental lag in attribution epistemic states....
Children's understanding of the nature, origins and consequences emotions has been intensively investigated over last 30-40 years. However, few empirical studies have looked at relation between emotion anxiety in children their results are mixed. The aim present study was to perform a preliminary investigation relationships understanding, anxiety, dysregulation, attachment security clinically anxious children. A sample 16 (age 8-12, eight girls/boys) assessed for (Test Emotion...
In the I/Lyn mouse strain a mutation on X chromosome results in deficiency of major calmodulin-regulated enzyme skeletal muscle, phosphorylase kinase. Calmodulin has been identified as delta-subunit kinase, and it is estimated that approximately 40% total calmodulin rabbit muscle associated with kinase hexadecamer (alpha, beta, gamma, delta)4. The absence reduction amount calmodulin. mechanisms affecting this were investigated by comparing abundance heterogeneities mRNAs between normal...
Abstract A cDNA encoding the skeletal muscle phosphorylase kinase catalytic subunit gamma has been isolated and sequenced. It contains 57 nucleotides of 5' nontranslated sequence, entire coding 1004 3' sequence. Probes derived from this gamma-cDNA were used to investigate expression gamma-messages in liver, heart, tissues. The results demonstrate that gamma-mRNAs expressed heart tissue are homologous gamma-mRNAs. However, liver tissue, no detected. implications these for understanding...
Theoretical models of anxiety have been developed in adult populations. The applicability these child samples has assessed using downward extensions the questionnaires to assess proposed theoretical mechanisms. This poses a challenge, as children are still process developing skills that being assessed. Psychometrically sound assessment tools therefore needed for this population, order ensure early detection mechanisms leading disorders children. study examined if metacognitions, which play...
There is an urgent need for expanding and enhancing autism spectrum disorder (ASD) samples, in order to better understand causes of ASD. In a unique public-private partnership, 13 sites with extensive experience both the assessment diagnosis ASD embarked on ambitious, 2-year program collect samples genetic phenotypic research begin analyses these samples. The was called Autism Simplex Collection (TASC). TASC sample collection began 2008 completed 2010, included nine from North America four...
Children's affective experiences and cognitive abilities have an impact on emotion understanding. However, their relative contribution, as well the possibility of interaction between them, has rarely been examined. The aim present study was to evaluate influence severe abuse learning difficulties simple complex components understanding in late childhood early adolescence. A total 28 older children young adolescents were selected for study. Half participants had suffered from abuse, half...
Theoretical views and empirical findings suggest interrelations among attachment security, emotion dysregulation anxiety in childhood adolescence. However, the associations three constructs have rarely been investigated children, no study has yet addressed these The aim of present was to test a model factors on sample 673 youths (age 9–16), using structural equation modelling. In accordance with theoretical conceptualisations, it hypothesised that security would relate help explain...
Theories of visual narrative understanding have often focused on the changes in meaning across a sequence, like shifts characters, spatial location, and causation, as cues for breaks structure discourse. In contrast, theory grammar posits that hierarchic "grammatical" structures operate at discourse level using categorical roles images, which may or not co-occur with coherence. We therefore examined relationship between coherence segmentation sequences "segmentation task" where participants...
Research from this laboratory has recently demonstrated that the omasal epithelium of sheep is capable absorbing dipeptides. In order to express proteins potentially responsible for mediated absorption small peptides, size-fractionated poly(A)+RNA (RNA) isolated epithelial tissue (average BW 67.5 kg) were injected into defolliculated Xenopus laevis oocytes. The ability oocytes with RNA or water absorb [14C]glycyl-L-sarcosine (Gly-Sar) media (usually pH 5.5) was compared. After 4 d (P < .02)...