A5101800619- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Prostate Cancer Treatment and Research
- Cervical Cancer and HPV Research
- Cancer, Lipids, and Metabolism
- Gynecological conditions and treatments
- Sarcoma Diagnosis and Treatment
- Minimally Invasive Surgical Techniques
- Radiation Therapy and Dosimetry
- Cancer and Skin Lesions
- Maternal and Neonatal Healthcare
- Synthesis and biological activity
- Drug Transport and Resistance Mechanisms
- Management of metastatic bone disease
- Viral-associated cancers and disorders
- Cancer Cells and Metastasis
- Genetic factors in colorectal cancer
- Genital Health and Disease
- Male Reproductive Health Studies
- Palliative and Oncologic Care
- Maternal and fetal healthcare
- Chemotherapy-induced cardiotoxicity and mitigation
- Intraperitoneal and Appendiceal Malignancies
- Neurofibromatosis and Schwannoma Cases
Brazilian National Association of Graduate Programs in Communication
2025
Universidade Federal do Sul e Sudeste do Pará
2025
Instituto do Câncer do Estado de São Paulo
2012-2021
Universidade de São Paulo
2006-2020
Hospital Israelita Albert Einstein
2016
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2007
Invasive cervical cancer (ICC) is the third most common malignant neoplasm affecting Brazilian women. Little known about impact of specific HPV genotypes in prognosis ICC. We hypothesized that genotype would ICC clinical presentation and survival.Women diagnosed with at Instituto do Câncer Estado de São Paulo (ICESP) between May 2008 June 2012 were included study followed until December 2015. was detected from formalin-fixed paraffin-embedded (FFPE) tumor tissue samples using Onclarity™...
Chalcones are organic chromophores with diverse biological applications and potential for use in various electronic devices due to their recognized optical properties. This research focuses on the synthesis, FT-NMR characterization, biotransformation of three azachalcones (1–3) using Exserohilum rostratum fungus, yielding novel compounds (1a–3a). In vitro assays against Gram-positive Gram-negative bacteria revealed promising pharmacological these new chromophores. A key structural...
The purpose of this study was to evaluate the clinical outcome and costs after implementation robotic surgery in treatment endometrial cancer, compared traditional laparoscopic approach.METHODS: In prospective randomized from 2015 2017, eighty-nine patients with carcinoma that clinically restricted uterus were (44 cases) (45 cases).We number retrieved lymph nodes, total time surgery, each surgical step, blood loss, length hospital stay, major minor complications, conversion rates...
•Intraoperative injury of the obturator nerve is not an infrequent complication gynecological surgeries.•This can occur in association with pelvic lymphadenectomy for uterine or cervical cancer.•This manuscript demonstrates alternative technique repair, when primary end to anastomosis possible.
L1 cell adhesion molecule (L1CAM) has been shown to be correlated with tumour progression, attributed its possible association epithelial-mesenchymal transition (EMT), characterised by the expression of vimentin and loss e-cadherin. Herein, we investigate associations between L1CAM clinicopathological parameters, as well e-cadherin, in carcinomas restricted cervix.The study was retrospective observational included 45 squamous (63.4%) 26 adenocarcinomas (36.6%) submitted primary surgical...
Robotic surgeries for cervical cancer have several advantages compared with laparotomic or laparoscopic surgeries. single-site surgery has many the multiport approach, but its safety and feasibility are not established in radical oncologic We report a case of Federation Gynecology Obstetrics (FIGO) stage IB1 carcinoma whose hysterectomy, sentinel lymph node mapping, dissection were entirely performed by robotic approach. The patient recovered very well, was discharged from hospital within 24 hours.
Few reports have described the clinical and prognostic characteristics of endometrial cancer, which is increasing worldwide, in large patient series Brazil. Our objective was to analyze clinicopathological characteristics, factors, outcomes patients with cancer treated followed at a tertiary Brazilian institution over 10-year period.This retrospective study included 703 diagnosed who were public academic hospital between 2008 2018. The following parameters analyzed: age diagnosis, race, body...
We report a case of uterine artery rupture in woman at 14 weeks’ gestation who presented with abdominal pain, tachycardia, and hypotension underwent diagnostic laparoscopy. During this procedure, spontaneous the left was diagnosed surgery converted into laparotomy. The bound to its origin distal portion. patient exhibited excellent postoperative recovery discharged two days after surgery. pregnancy continued without other maternal or fetal complications, delivered healthy newborn via...
Evaluate feasibility and safety of a novel technique for uterine morcellation in patients scheduled laparoscopic treatment gynecologic malignances. Prospective pilot study women with endometrial cancer which uterus removal was realistic concern due to both organ size proportionality. Brief description: after completion total hysterectomy bilateral anexectomy, nylon polyurethane Lapsac® is vaginally inserted into the abdomen; specimen placed inside pouch that will be closed rotated 180...
Pseudomyxoma peritonei (PMP) is a clinical condition initially thought to be related ovarian mucinous tumors; however, immunohistochemistry and molecular biology techniques have convincingly made the link appendiceal neoplasms, resulting in changes histologic approaches. The objective of this study was compare immunohistochemical profile tumors associated with PMP intestinal neoplasms without PMP. retrospective included 28 selected from files Division Surgical Pathology University Sao Paulo...
3176 Background: Previously we showed that etoposide oleate (ETO)associated with a cholesterol-rich microemulsion (LDE) forms stable complex is taken up by malignant cells. LDE-ETO retains the in vitro anti-proliferative activity of drug and markedly reduces toxicity to animals. In this study, plasma kinetics LDE:ETO ability concentrate tumor after injection into patients were tested. Methods: labeled [3H]etoposide [14C]-Cholesteryl Oleate (CO) was intravenously injected 10 ovarian cancer...
<h3>Objectives</h3> Identification of DNA mismatch repair (MMR) deficiency has been proposed as a screening strategy for Lynch Syndrome (LS) in endometrial cancer (EC) patients and is useful predicting tumor sensitivity immune checkpoint blockade therapies. The proportion EC with MMR reported to be 26%, around 3% may attributed LS. present study aims identify clinicopathological features tested tumoral expression Brazilian center. <h3>Methods</h3> 479 treated from 2010 through 2020 at...
<h3>Objectives</h3> To evaluate pathologic findings and access risk factors in premenopausal patients with hormone receptor-positive metastatic breast cancer undergoing bilateral salpingo-oophorectomy (BSO) for supression. <h3>Methods</h3> We retrospectively analyzed data of 170 who had been submitted to BSO ovarian supression between 2009 2021 at a terciary hospital São Paulo, Brazil. All were the time surgery, but none known metastasis. Patients preoperative suspicion malignancy ovaries...
<h3>Objectives</h3> Evaluation of ovarian cysts (OCy) are specially challenging in patients with a history breast cancer (BC). We aimed to characterize population BC submitted oophorectomy for OCy and establish risk factors malignant findings on surgical specimen. <h3>Methods</h3> All treated between 2008–2021 at tertiary hospital,were retrospectively reviewed. <h3>Results</h3> 66 were eligible.Characteristics described table 1. Most (71.2%) had no cancer/benign lesions the specimens...