A5012426321- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Bipolar Disorder and Treatment
- Bullying, Victimization, and Aggression
- School Health and Nursing Education
- Child and Adolescent Psychosocial and Emotional Development
- Taxation and Legal Issues
- Higher Education Learning Practices
- Educational Practices and Policies
- Health Promotion and Cardiovascular Prevention
- Dutch Social and Cultural Studies
- Neurotransmitter Receptor Influence on Behavior
- HIV Research and Treatment
- Electrolyte and hormonal disorders
- Restless Legs Syndrome Research
- HIV/AIDS Research and Interventions
- Tryptophan and brain disorders
- Advanced MRI Techniques and Applications
- Pharmacological Effects and Toxicity Studies
Rijnstate Hospital
2021-2023
University of Copenhagen
2023
Radboud University Nijmegen
2021
Radboud University Medical Center
2021
Amsterdam University of Applied Sciences
2018
Abstract Background Electroconvulsive therapy (ECT) is the most effective intervention for patients with treatment resistant depression. A clinical decision support tool could guide patient selection to improve overall response rate and avoid ineffective treatments adverse effects. Initial small-scale, monocenter studies indicate that both structural magnetic resonance imaging (sMRI) functional MRI (fMRI) biomarkers may predict ECT outcome, but it not known whether those results can...
Electroconvulsive therapy (ECT) is one of the most effective treatments for severe depressive disorders. A recent multi-center study found no consistent changes in correlation-based (undirected) resting-state connectivity after ECT. Effective (directed) may provide more insight into working mechanism ECT.We investigated whether there are connectivity.This included data from 189 patients suffering unipolar depression and 59 healthy control participants. Longitudinal were available 81 24...
Abstract An influential hypothesis holds that depression is related to a neural excitation/inhibition imbalance, but its role in the treatment of remains unclear. Here, we show unmedicated patients with severe demonstrated reduced inhibition brain-wide resting-state networks relative healthy controls. Patients using antidepressants showed was higher than and comparable controls, they still suffered from depression. Subsequent electroconvulsive therapy (ECT) depressive symptoms, effectiveness...
We describe a case of an adolescent male with Niemann-Pick Type C (NP-C), neurodegenerative lysosomal lipid storage disorder, who presented recurrent catatonia which required repeated treatment electroconvulsive therapy (ECT). During the ECT-course, seizure threshold increased substantially, leading to questions about influence NP-C on neuronal excitability. In this exemplary ECT-patient, was diagnosed not until after first ECT-course when initial psychopharmacology for had failed and...
Contradictory data have been reported concerning neuropsychiatric side effects of the first-line antiretroviral drug dolutegravir, which may be partly due to lack control groups or psychiatric assessment tools. Using validated self-report questionnaires, we compared mood and anxiety (DASS-42), impulsivity (BIS-11), substance use (MATE-Q) between dolutegravir-treated dolutegravir-naive people living with HIV (PLHIV). We analyzed 194, mostly male, PLHIV on long-term treatment whom 82/194...
Abstract Background Electroconvulsive therapy (ECT) is the most effective intervention for patients with treatment resistant depression. A clinical decision support tool could guide patient selection to improve overall response rate and avoid ineffective treatments adverse effects. Initial small-scale, mono-center studies indicate that both structural magnetic resonance imaging (sMRI) functional MRI (fMRI) biomarkers may predict ECT outcome, but it not known whether those results can...