A5079874250- Functional Brain Connectivity Studies
- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Mental Health Research Topics
- Electroconvulsive Therapy Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Transcranial Magnetic Stimulation Studies
- Treatment of Major Depression
- Stress Responses and Cortisol
- Autism Spectrum Disorder Research
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Attention Deficit Hyperactivity Disorder
- Memory and Neural Mechanisms
- Neural dynamics and brain function
- Neuroendocrine regulation and behavior
- Neural and Behavioral Psychology Studies
- Neurotransmitter Receptor Influence on Behavior
- Health, Environment, Cognitive Aging
- Neuroscience and Neuropharmacology Research
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Eating Disorders and Behaviors
- Traumatic Brain Injury Research
Amsterdam University Medical Centers
2018-2025
University of Amsterdam
2016-2025
Amsterdam Neuroscience
2017-2025
Amsterdam UMC Location University of Amsterdam
2014-2025
Spinoza Centre for Neuroimaging
2016-2024
University of Copenhagen
2023
Vrije Universiteit Amsterdam
2022-2023
Ziekenhuisnetwerk Antwerpen Stuivenberg
2021
Amsterdam Institute for Addiction Research
2015-2021
University Medical Center Utrecht
2021
The promise of machine learning has fueled the hope for developing diagnostic tools psychiatry. Initial studies showed high accuracy identification major depressive disorder (MDD) with resting-state connectivity, but progress been hampered by absence large datasets. Here we used regular and advanced deep algorithms to differentiate patients MDD from healthy controls identify neurophysiological signatures depression in two largest datasets MDD. We obtained functional magnetic resonance...
Acute stress is associated with a sensitized amygdala. Corticosteroids, released in response to stress, are suggested restore homeostasis by normalizing/desensitizing brain processing the aftermath of stress. Here, we investigated effects corticosteroids on amygdala using functional magnetic resonance imaging. Since exert rapid nongenomic and slow genomic effects, administered hydrocortisone either 75 min (rapid effects) or 285 (slow before scanning randomized, double-blind,...
Acute psychological stress can trigger normal and abnormal motivated behaviors such as reward seeking, habitual behavior, drug craving. Animal research suggests that effects may result from actions of catecholamines glucocorticoids converge in brain regions regulate incentive processing. At present, however, little is known about the acute on these circuits humans. During functional magnetic resonance imaging (fMRI), twenty-seven healthy young women performed a modified version monetary...
Exposure to severe stressors increases the risk for psychiatric disorders in vulnerable individuals, but can lead positive outcomes others. However, it remains unknown how stress affects neural functioning humans and what factors mediate individual differences sequelae of stress. The amygdala is a key brain region involved threat detection fear regulation, previous animal studies have suggested that sensitizes responsivity reduces its regulation by prefrontal cortex. In this study, we used...
Corticosteroids are potent modulators of human higher cognitive function. They released in response to stress, and thought be involved the modulation function by inducing distinct rapid nongenomic, slow genomic changes, affecting neural plasticity throughout brain. However, their exact effects on correlates higher-order as performed prefrontal cortex at brain system level remain elucidated. Here, we targeted these time-dependent corticosteroids processing humans using a working memory (WM)...
Impaired mood regulation is a key deficit of major depressive disorder that primarily mediated by an interaction between the paralimbic cortex (i.e., orbitofrontal, cingulate, insular, parahippocampal, and temporopolar cortices) limbic regions. The authors investigated whether depressed patients healthy comparison subjects have differences in cortical thickness potential are evident only during state or trait related.Forty with first episode participated: 20 medication-naive currently...