A5051446648- Virus-based gene therapy research
- Bone Tumor Diagnosis and Treatments
- RNA Research and Splicing
- Ear and Head Tumors
- Muscle Physiology and Disorders
- Bone fractures and treatments
- Mesenchymal stem cell research
- Sarcoma Diagnosis and Treatment
- Viral Infections and Immunology Research
Brigham and Women's Hospital
2024
Harvard University
2024
Kyungpook National University
2022
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is known to play multiple biological roles by regulating transcriptional expression, RNA splicing, stability, and chromatin structure in a tissue-dependent manner. The role of hnRNPU skeletal muscle development maintenance has not been previously evaluated. In this study, specific knock out mice utilized evaluated mass immune cell infiltration through development. By 4 weeks, muscle-specific knockout revealed Ly6C+ monocyte into muscle,...
Although there are growing demands for stem cell-based therapy companion animals in various diseases, a few clinical trials have been reported. Moreover, most of them the results from only one or times cell injection.The aim this study is to describe long-term treatment with allogeneic adipose-derived cells (ASCs) dog rheumatoid arthritis (RA), which rare canine disease.The RA received intravascular injection ASCs derived two healthy donors once month 11 months. To assess therapeutic effects...
Myxoid pleomorphic liposarcoma is characterized by pathological features of both and myxoid liposarcoma, as the name suggests. In this case, a was observed in 5-year-old male African pygmy hedgehog. It consisted ~60% substance area with proliferating round cells ~30% neoplastic cells. The subject presented extrapulmonary metastasis, but good prognosis during 6 months follow-up, which similar to characteristics liposarcoma. histopathological may reflect either or depending on proportion each...