- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Intraperitoneal and Appendiceal Malignancies
- Endometriosis Research and Treatment
- Reproductive Biology and Fertility
- Uterine Myomas and Treatments
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Cancer Immunotherapy and Biomarkers
- Gynecological conditions and treatments
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Lymphoma Diagnosis and Treatment
- Surgical Simulation and Training
- Medical Imaging Techniques and Applications
- Ovarian function and disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Immune Cell Function and Interaction
- Renal cell carcinoma treatment
- Chromatin Remodeling and Cancer
- Neuroblastoma Research and Treatments
- Enhanced Recovery After Surgery
- Urinary and Genital Oncology Studies
Augusta University
2021-2024
Carolinas Medical Center
2003-2020
Levine Cancer Institute
2015-2020
Carolinas Healthcare System
2016-2018
Cleveland Clinic
2009-2017
UPMC Hillman Cancer Center
2017
University of Oklahoma Health Sciences Center
2017
Brown University
2017
Summa Akron City Hospital
2017
The Ohio State University Wexner Medical Center
2017
From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured three planes ovarian volume calculated using prolate ellipsoid formula. The upper limit normal for 18 cm3 premenopausal 8 postmenopausal women. In patients with scans, mean volumes decreased from 6.8 3.0...
From 1962 to 1985, 2201 patients with invasive cervical cancer were staged, evaluated, and treated at the University of Kentucky Medical Center. After a thorough evaluation, 25 cases (1.1%) fulfilled histologic criteria for small cell defined by Reagan coworkers. These computermatched age, disease stage, lesion size large nonkeratinizing keratinizing squamous cancer. Morphometric analyses nuclear maximum diameter performed on all without knowledge type. Small cancers characterized area 160...
BackgroundA phase 2, randomized, placebo-controlled trial was conducted in women with recurrent epithelial ovarian carcinoma to evaluate the efficacy and safety of motolimod—a Toll-like receptor 8 (TLR8) agonist that stimulates robust innate immune responses—combined pegylated liposomal doxorubicin (PLD), a chemotherapeutic induces immunogenic cell death.Patients methodsWomen ovarian, fallopian tube, or primary peritoneal were randomized 1 : receive PLD combination blinded motolimod placebo....
Ninety-four patients with squamous cell carcinoma invading the cervical stroma to a depth of >3.0-5.0 mm 7 or less in horizontal spread (FIGO Stage IA2) were evaluated. Depth and lateral extent stromal invasion verified using an ocular micrometer. Cell type lymph vascular space (LVSI) recorded each case. Patients treated primarily by radical hysterectomy pelvic lymphadenectomy, those node metastases offered postoperative radiation. Following treatment, seen at 3-month intervals for 2 years,...
From 1973 to 1987, 16 patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I serous papillary endometrial carcinoma were evaluated treated at the University Kentucky Medical Center (Lexington, KY). All 60 years age or older, all postmenopausal. Patients total abdominal hysterectomy, bilateral salpingo-oophorectomy, paraaortic lymph node sampling, 38% noted have more extensive disease than appreciated clinically. Nine given adjuvant postoperative radiation. Seven...
To identify potential prognostic indicators of ovarian cancer and targets for therapeutic strategies, mRNA differential display was used to analyze gene expression differences in normal, benign, cancerous tissue. One cDNA isolated by this technique, Op18/stathmin, is a highly conserved that reported have many different functions within cell, including signal transduction, control the cell cycle, regulation microtubules. Quantitative Northern blot analysis 12 malignant samples, 8 benign...