- Metabolomics and Mass Spectrometry Studies
- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Diet and metabolism studies
- Tea Polyphenols and Effects
- Gut microbiota and health
- Fermentation and Sensory Analysis
- Phytochemicals and Antioxidant Activities
- Alcohol Consumption and Health Effects
- Probiotics and Fermented Foods
- Protein Hydrolysis and Bioactive Peptides
- Biochemical effects in animals
- Ruminant Nutrition and Digestive Physiology
- Ginseng Biological Effects and Applications
- Genetic and phenotypic traits in livestock
- Phytoestrogen effects and research
- Biochemical Analysis and Sensing Techniques
- Coffee research and impacts
- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Horticultural and Viticultural Research
- Meat and Animal Product Quality
- Reproductive Physiology in Livestock
University of Alberta
2015-2019
Universitat de Barcelona
2012-2018
The Metabolomics Innovation Centre
2018
Extreme Science and Engineering Discovery Environment
2015
Instituto de Gestión de la Innovación y del Conocimiento
2012-2015
The Human Metabolome Database or HMDB (www.hmdb.ca) is a web-enabled metabolomic database containing comprehensive information about human metabolites along with their biological roles, physiological concentrations, disease associations, chemical reactions, metabolic pathways, and reference spectra. First described in 2007, the now considered standard resource for studies. Over past decade has continued to grow evolve response emerging needs metabolomics researchers continuing changes web...
Bovine milk is a nutritionally rich, chemically complex biofluid consisting of hundreds different components. While the chemical composition cow's has been studied for decades, much this information fragmentary and very dated. In an effort to consolidate update information, we have applied modern, quantitative metabolomics techniques along with computer-aided literature mining obtain most comprehensive up-to-date characterization constituents in commercial milk. Using nuclear magnetic...
The Mediterranean diet (MD) is considered a dietary pattern with beneficial effects on human health. aim of this study was to assess the effect an MD urinary metabolome by comparing subjects at 1 and 3 years follow-up, after supplemented either extra-virgin olive oil (MD + EVOO) or nuts Nuts), those advice follow control low-fat (LFD). Ninety-eight nondiabetic volunteers were evaluated, using metabolomic approaches, corresponding EVOO (n = 41), Nuts 27), LFD 30) groups. 1H NMR profiles...
The purpose of this study was to examine the effects two pasture feeding systems-perennial ryegrass (GRS) and perennial white clover (CLV)-and an indoor total mixed ration (TMR) system on (a) rumen microbiome; (b) fluid milk metabolome; (c) assess potential distinguish from different systems by their respective metabolomes. Rumen collected nine cannulated cows under in early, mid late lactation, raw samples were ten non-cannulated mid-lactation each systems. microbiota present liquid solid...
Moderate wine consumption is associated with health-promoting activities. An H-NMR-based metabolomic approach was used to identify urinary differences of moderate intake in the setting a prospective, randomized, crossover, and controlled trial. Sixty-one male volunteers high cardiovascular risk factors followed three dietary interventions (28 days): dealcoholized red (RWD) (272mL/day, polyphenol control), alcoholized (RWA) (272mL/day) gin (GIN) (100mL/day, alcohol control). After each...
Metabolomics approach identified markers of intake functional beverage based on grape skin extracts.
Little is known about the metabolome fingerprint of pulse consumption. The study robust and accurate biomarkers for dietary assessment has great value nutritional epidemiology regarding health benefits their mechanisms. To characterize fingerprinting pulses (chickpeas, lentils, beans), spot urine samples from a subcohort PREDIMED were stratified using validated food frequency questionnaire. Urine nonpulse consumers (≤4 g/day intake) habitual (≥25 analyzed 1H nuclear magnetic resonance (NMR)...
Functional tea beverages have emerged as a novel approach to achieving health benefits associated with tea. The use of metabolomics may improve the evaluation their consumption and effects. current study aimed at exploring urinary signature exposure functional high-catechin (HCT) using untargeted NMR-based metabolomics. Ten volunteers participated in crossover intervention study. Individuals consumed an HCT or control beverage over period 28 days. Multilevel partial least-squares...
Diet plays an important role in the prevention and development of chronic diseases. Interventional observational studies have provided evidence health benefits dietary bioactive compounds. The assessment intake has been estimated using self‐reported questionnaires, which provide less reliable data than nutritional biomarkers. Nutrimetabolomics proposed as a tool for discovering new biomarkers exposure. Different clinical provides complementary information about exposure, thus discovery In...