Smoking is a known risk factor for snoring, and reported to be associated with an increased prevalence of obstructive sleep apnea syndrome (OSAS). The purpose this was determine the relationship smoking severity OSAS examine what local histological changes in uvular mucosa patients might influence relationship.Fifty-seven subjects were included classified according history severity. Twenty-eight heavy smokers 29 nonsmokers; these 57 divided moderate or severe OSAS. Histologic evaluated all...

KEY POINTS Human nasal cavity samples were collected, and presence of microplastics evaluated. Microplastics present, major types polyethylene, polyester, acrylic polymer, polypropylene. Further research is needed regarding its clinical impact on human cavity.

This study aimed to evaluate the hypothesis that relief of nasal obstruction in subjects with obstructive sleep apnea (OSA) would lead reduce OSA severity and discuss available evidence on clinical efficacy surgery as a treatment modality for OSA.Twenty-five who had reduced patency cavity narrowing retroglossal or retropalatal airways were diagnosed underwent surgery, such septoplasty turbinoplasty correct pathologies. The effect was quantified by measuring minimal cross-sectional area (MCA)...

Ginseng saponin has long been used as a traditional Asian medicine and is known to be effective in treating various kinds of pain. Ginsenoside Rf one the biologically active saponins found ginseng. We evaluated ginsenoside Rf's antinociceptive anti-inflammatory effects, its mechanism action on adrenergic serotonergic receptors, an incisional pain model. Mechanical hyperalgesia was induced via plantar incision rats followed by intraperitoneal administration increasing doses (vehicle, 0.5...

The main mechanism of pathogenesis which causes systemic complications in obstructive sleep apnea (OSA) patients is believed to be intermittent hypoxia-induced intermediary effect and it depends on the burden oxidative stress during sleep. We aimed search predictive markers reflect with OSA whether excessive telomere length shortening a characteristic feature that can assess levels. used quantitative PCR measure using peripheral blood genomic DNA. Telomere lengths were compared an age- body...

Overexpression of human epidermal growth factor receptor type 2 (HER2) is considered as a prognostic breast cancer, which positively associated with recurrence when cancer metastasizes to the lymph nodes. Here, we expressed single variable domain on heavy chain (VHH) form anti-HER2 camelid antibody in tobacco plants and compared its vitro anticancer activities full size antibody. The gene expression cassette containing VHH fused IgG Fc region KDEL endoplasmic reticulum (ER) (VHH-FcK) was...

Pectus bar removal is the final stage of procedure for minimally invasive repair pectus excavatum. Based on our experience with one largest scale data, we would like to address important issues in removal, such as appropriate duration maintenance, techniques and strategies avoid complications.Between September 1999 August 2015, operated 2,553 patients excavatum carinatum using bars a approach. Among them, 1,821 (71.3%) underwent deformity repair, their data were analyzed retrospectively...

Eosinophil cationic protein (ECP) is present in eosinophil granules. It has been associated with eosinophil-associated disorders.We compared serum ECP levels allergic and non-allergic rhinitis patients evaluated the association count total IgE level.We retrospectively reviewed medical records categorized enrolled into (AR) (NAR) groups. ECP, count, were both The between level was further according to commonly detected specific antigens.Six hundred ten adults included study. In AR group...

Abstract The function of high-mobility group box 1 (HMGB1) varies according to its location. However, the translocation mechanism behind HMGB1 remains unclear. We hypothesize that type 2 helper T cell (Th2) cytokines are involved in upper airway epithelium. investigated using Th2 cytokine stimulation and examined clinical significance allergic rhinitis (AR). Cytoplasmic extracellular were increased AR. Inhibiting with glycyrrhizic acid (GA) decreased level antigen-specific immunoglobulin E...

This study aimed to assess the accuracy and clinical efficacy of a wrist-worn device that is based on peripheral arterial tonometry (watch-PAT) evaluate surgical results obstructive sleep apnea (OSA) syndrome subjects.Thirty-five subjects who were diagnosed with OSA underwent surgeries such as septoplasty, tonsillectomy, or uvuloplasty correct their airway collapse, participated in this study; watch-PAT-derived respiratory disturbance index (RDI), hypopnea (AHI), lowest oxygen saturation,...

Abstract Background This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults . Methods In this cross-sectional study, geriatric subjects (aged > 50 years) who underwent neurocognitive function tests were included. Overall, 137 enrolled, was conducted at Chung-Ang University, Seoul, Korea. Olfactory measured by obtaining scores of system using 2-phenylethyl alcohol, n-butanol, YSK test. Time taken each...

Olfactory impairment is associated with dementia and a potential early biomarker of cognitive decline. We developed novel olfactory threshold test called Sniff Bubble using rose odor-containing beads made 2-phenylethyl alcohol. aimed to define cut-off scores for this tool help identify decline among elderly people. In total, 162 people (mean age ± SD: 73.04 8.73 years) were administered neurocognitive tests. For analyses, we divided the participants into two groups based on functioning,...

Department of Chemistry, Chung Ang University, Seoul 156-756, KoreaReceived October 2, 2002Key Words : Copper thin film by MOCVD, selenide selenium vapor depositionRecently, the preparation copper hasattracted much attention particular interest due to theirwide applications such as electronic and electro-opticaldevices.

A narrow internal auditory canal (IAC) with duplication is a rare anomaly of the temporal bone. It associated congenital sensorineural hearing loss. Aplasia or hypoplasia vestibulocochlear nerve may cause We present an unusual case isolated IAC that was detected by CT scan. In this case, divided bony septum into empty stenotic inferoposterior portion and large anterosuperior containing facial clearly delineated on MRI.

Primary nasopharyngeal tuberculosis, defined as an isolated tuberculosis infection of the nasopharynx without systemic or pulmonary disease, is rare, even in areas endemic for tuberculosis. It challenging ENT specialists to diagnose primary at early stage. In this report, we describe a new case focusing on its nasopharyngoscopic features and radiological findings that can help understanding aid accurate diagnosis unusual disease entity. Our experience suggests although relatively rare it...

Objectives. Few studies have reported combined analyses of the microbiome adenoids and tonsils in pediatric patients with snoring, correlations adenotonsillar clinical characteristics not been evaluated to date. The aim this study was characterize determine its subjective symptoms snoring levels regional mucosal immune molecules.Methods. Twenty-four children who underwent tonsillectomy adenoidectomy owing were enrolled cross-sectional conducted between August 2017 December 2018....

Microplastics were identified in nasal irrigations Polypropylenes, which the main component of nozzle, commonly Additional studies are needed to understand biological relevance microplastics irrigations.

The utilization of fillers, notably hyaluronic acid, has increased due to their proven effectiveness, versatility, and generally favorable safety profile. In the field rhinoplasty, acid dermal fillers have been employed for correction nasal deformities surface irregularities. Nevertheless, intricate vascular network region, involving anastomoses between external internal carotid arteries, predisposes it serious complications. We report a case severe septal ulcer secondary local ischemia...