- Oral microbiology and periodontitis research
- Periodontal Regeneration and Treatments
- Orthodontics and Dentofacial Orthopedics
- Anorectal Disease Treatments and Outcomes
- Dental Implant Techniques and Outcomes
- Iron Metabolism and Disorders
- Pelvic floor disorders treatments
- Enzyme Production and Characterization
- Hemoglobinopathies and Related Disorders
- Phytase and its Applications
- Diverticular Disease and Complications
- Streptococcal Infections and Treatments
- Dental Health and Care Utilization
- Endodontics and Root Canal Treatments
- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Food composition and properties
- Food Quality and Safety Studies
- Liver Disease Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Colorectal Cancer Surgical Treatments
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Oral and gingival health research
- Facial Rejuvenation and Surgery Techniques
Shuguang Hospital
2020-2025
Shanghai University of Traditional Chinese Medicine
2017-2025
Stomatology Hospital
2018-2024
Peking University
2010-2024
King University
2019-2022
Jeonbuk National University
2021
Peking University First Hospital
2018
Northeast Ohio Medical University
2017
Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine
2017
Tianjin University
2016-2017
Crohn's disease (CD) is a chronic, recurrent gastrointestinal disorder characterized by complex etiology. Among its perianal complications, anal fistulas represent challenging comorbidity. With the increase of surgical options, comprehensive bibliometric analysis was deemed necessary to consolidate vast array research in this field. We extracted 1608 articles spanning from 1 January 1994, May 2024, Web Science Core Collection. Using VOSviewer, CiteSpace, and Scimago Graphica for visual...
Abstract Objective: Ferritin, an iron-binding protein, is ubiquitous and highly conserved; it plays a crucial role in inflammation, which the main symptom of periodontitis. Full-length cDNA library analyses have demonstrated abundant expression ferritin human periodontal ligament. The aims present study were to explore how regulated by local investigate its functions mechanisms action process Methods: Human gingival tissues collected from periodontitis patients healthy individuals....
High horseshoe-shaped anal fistula (HHAF) is a complex disease that manifests in the perianal region and typically requires surgical intervention for treatment. However, current therapeutic approaches are limited by high rates of postoperative recurrence incontinence. To overcome limitations traditional approaches, we introduce bared external sphincter (BEAS) technique. Our study aims to compare clinical efficacy BEAS surgery with modified Hanley procedure real-world setting.
Abstract Objectives To investigate whether anemia of inflammation (AI) occurs in periodontitis patients and to further explore underlying pathogenesis periodontitis‐related AI by an experimental model. Background Previous studies have reported could show a tendency toward AI. However, the relationship between remains unclear, related pathological mechanisms not been identified. Materials Methods Periodontal clinical parameters, inflammatory markers, anemia‐related indicators were compared 98...
Abstract Anemia of inflammation (AI) is associated with inflammatory diseases, and inflammation-induced iron metabolism disorder the major pathogenic factor. Earlier studies have reported a tendency AI in periodontitis patients, but explicit relationship possible pathological mechanisms remain unclear. Here, analyses both patients mouse model ligature-induced experimental showed that was lower levels hemoglobin hematocrit evidence systemic (increased white blood cell levels) restriction (low...
Abstract Although fluoride has been widely used as a preventive agent for dental caries, the effects of on activities biofilms in different stages cariogenic biofilm formation are less studied. This study was designed to investigate antibiofilm activity sodium during early and mature Streptococcus mutans ( S. ) formation. were formed saliva-coated hydroxyapatite disks. In (0–46 h) (46–94 stages, treated with concentrations (250, 500, 1000, 2000 ppm; 5 times total, 1 min/treatment)....
Abstract Objectives To quantitatively assess periodontal soft tissue changes, including gingival thickness and keratinized gingiva width after periodontally accelerated osteogenic orthodontics (PAOO) surgery by digital measurements. Methods This study enrolled 15 maxillaries with 89 anterior teeth 16 mandibles 94 from Chinese adult patients skeletal Angle Class III malocclusion for whom PAOO was proposed during orthodontic treatment. Intraoral scanning cone beam computed tomography (CBCT)...
BackgroundTo assess the alterations in gingival thickness and occurrence recession subsequent to orthodontic-orthognathic treatment of mandibular incisors skeletal Class III identify risk factors associated with recession.MethodsIn this retrospective cohort study, we enrolled 33 patients exhibiting malocclusion, totaling 131 incisors, who were undergoing orthodontic- orthognathic that did not involve extraction teeth. The subjects categorized into surgery group (S; n=17; ANB=-5.55±3.26;...
Introduction High horseshoe-shaped anal fistula (HHAF) is a complicated and challenging condition that presents considerable obstacles in treatment. We are presently investigating novel surgical technique involving combination of multi-incision tube-dragging therapy, laser closure (MITD-LaC) for the management HHAF. Due to current scarcity rigorous evidence evaluating this approach, it essential perform well-designed randomized controlled trial compare effectiveness new method with incision...
The aims of this study were to investigate the population pharmacokinetic (PPK) characteristics tacrolimus in Chinese children with nephrotic syndrome and apply it clinical practice.A total 137 concentrations from 61 patients collected routine therapeutic drug monitoring data between 2011 2018. Population modeling was performed nonlinear mixed-effects model (NONMEM) program, using a one-compartment first-order absorption elimination. mean estimate values clearance (CL/F) volume distribution...
Introduction Postoperative recurrence and related complications are common to poor outcomes in patients with anal fistula (AF). Due being associated short-term long-term cure rates, perioperative have received widespread attention following AF surgery. This study aims identify a set of predictive factors develop risk prediction models for We plan validate models, using information collected through WeChat patient-reported questionnaire system combined clinical, laboratory imaging findings...
Introduction Periodontal regeneration surgery has been widely used to deal with intrabony defects. Modified minimally invasive surgical technique (M-MIST) is designed isolated interdental defects, and achieved satisfactory periodontal regenerative effect. Bio-Oss Collagen, as a bioactive material, applied for regeneration. It similar human cancellous bone, the ability promote bone formation; furthermore, it exceptional plasticity spatial stability. The combination of different materials...
An antifungal lipopeptide iturin A with strong activity against Fusarium oxysporum was produced by honey isolated strain Bacillus amyloliquefaciens BH072. For large-scale biocontrol application, the effect deeply demonstrated structure and mode of action. Cyclic second were determined based on situ acid hydrolysis Fourier Transformed-Infra Red (FT-IR) Spectra analysis. Structure α-helix predicted which might be associated activity. Afterwards, mechanism F. investigated from fungal cell wall...
Objective: To establish a quantitative three-dimensional method based on intraoral scan to evaluate the changes of soft tissue, and supracrestal gingival thickness (SGT) in skeletal class Ⅲ patients induced by periodontal regenerative corticotomy surgery (PRCS). Methods: Twenty-two systematically periodontally healthy (4 males 18 females, aged between 19 35 years), who were need combined orthodontic-orthognathic treatment referred Department Periodontology from Orthodontics Oral...