A5102964666- Cardiovascular Disease and Adiposity
- Orthopaedic implants and arthroplasty
- Venous Thromboembolism Diagnosis and Management
- Hip and Femur Fractures
- Acute Ischemic Stroke Management
- Mechanical Circulatory Support Devices
- Retinal and Optic Conditions
- Cardiac Arrest and Resuscitation
- Gallbladder and Bile Duct Disorders
- Diet and metabolism studies
- Drug-Induced Adverse Reactions
- Digital Imaging for Blood Diseases
- Cutaneous Melanoma Detection and Management
- Mental Health and Psychiatry
- Cytokine Signaling Pathways and Interactions
- Bone fractures and treatments
- IL-33, ST2, and ILC Pathways
- Adipokines, Inflammation, and Metabolic Diseases
- Kawasaki Disease and Coronary Complications
- Cardiovascular Effects of Exercise
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- Coronary Artery Anomalies
- Fibroblast Growth Factor Research
- Trauma Management and Diagnosis
University of Cambridge
2019-2025
University of Missouri–Kansas City
2019-2024
University of Pennsylvania
2021-2024
Orlando Health
2023
University of Miami
2023
Rollins College
2023
University of Central Florida
2023
Florida College
2023
Northside Hospital
2021-2023
Burroughs Wellcome Fund
2023
Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses formulated explain the etiology PASC, including viral persistence, chronic inflammation, hypercoagulability, autonomic dysfunction. Here, we propose mechanism that links all four in single pathway provides actionable insights for therapeutic interventions. We find PASC are associated with...
Here we provide direct evidence that fibroblast growth factor 23 (FGF23), a phosphaturic hormone elevated in chronic kidney disease, is proarrhythmic. FGF23 acutely triggered ventricular arrhythmias and prolonged corrected QT interval (QTc) isolated mouse hearts vivo. also increased Ca 2+ levels muscle tissue. Blockade of the FGF receptor 4 signaling pathway using monoclonal antibody ameliorated arrhythmias, QTc prolongation, induced by FGF23, may represent potential therapeutic target disease.
Little is known about the pathophysiology of delusional infestation (DI), a psychodermatologic condition in which patients have fixed, false belief being infested with parasites or inanimate material their skin, despite lack objective evidence. Because some states, such as schizophrenia and psychotic state bipolar disorder been found to be associated brain structural functional abnormalities, literature review was conducted summarize available data on abnormalities that are DI. A cases...
<h3>Introduction</h3> During ERCP (Endoscopic Retrograde Cholangiopancreatography), endoscopists make an initial assessment of the major duodenal papilla (MDP) to determine optimal approach for common bile duct (CBD) cannulation and a safe limit sphincterotomy. Cannulation requires engagement followed by angular adjustment, step angle, attain deep cannulation. This angle plays important role in determining ease CBD A sphincterotomy should be long enough effectively open ampullary orifice...
Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disease characterized by linear deposition along the dermo-epidermal junction on direct immunofluorescence (DIF). LABD appears clinically as erythematous polycyclic lesions in younger patients but can show considerable phenotypic heterogeneity older patients, often leading to misdiagnoses such pemphigoid, pemphigus vulgaris, Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), or other conditions. Cases of...
Normal Pressure Hydrocephalus (NPH) occurs when there is an accumulation of cerebrospinal fluid due to impeded flow or excess production, resulting in gait and memory impairment urinary incontinence. The authors present the case a 67-year-old male, who had symptoms for year prior being diagnosed. His neurological exam was significant slow, unsteady wide-based gait. No underlying cause his NPH found. He underwent shunt procedure following which he made complete recovery.
<h3>Objective:</h3> To assess stroke knowledge in the US layperson population. <h3>Background:</h3> One of biggest barriers to thrombolytic therapy for acute is time presentation from symptom onset. This national survey adults aims identify reasons why people delay seeking care. <h3>Design/Methods:</h3> A sample were surveyed via a web-based using third party polling service. The consisted 15 multiple choice questions. Data analyzed JMP Pro 16 Mac. <h3>Results:</h3> majority respondents (n=...
Introduction Fat Embolism consequent to Triolein (T) intravenous injection in rats induces severe histopathologic pulmonary damage at 48 hours mostly related vasculitis, peribronchial and septal inflammation with an increase mast cells, eventually, organ fibrosis. We previously reported that the hearts of same animals did not show vasculitis coronary arteries branches, or cells. The objective this study was determine if T treatment by 10 weeks induced changes cardiac gene expression...
Distal clavicle excision (DCE) for acromioclavicular (AC) joint primary osteoarthritis and post-traumatic arthritis has been shown to have good excellent outcomes. However, there are studies that report significant rates of residual AC pain distal instability after open arthroscopic techniques. We describe a surgical technique management osteoarthritis, arthritis, revision DCE involves with ligament reconstruction tendon interposition arthroplasty. It provides stability can theoretically...
Abstract Aim Distal femoral fractures account for 3–6% of all fractures. Current management distal involve reducing bone fragments and placing a locking plate against it. In this study, the surgeon used ‘selective approach’, whereby only key in comminuted fracture were reduced fixed whilst rest either removed or left unreduced/unfixed. Method All patients underwent AxSOS plate/less invasive stabilisation system (LISS) surgery their after adopting “selective approach” during pre-surgical...