A5030817561- Hepatitis C virus research
- Global Health Care Issues
- Hepatitis B Virus Studies
- Global Maternal and Child Health
- Child Nutrition and Water Access
- Healthcare Policy and Management
- HIV, Drug Use, Sexual Risk
- Global Public Health Policies and Epidemiology
- Healthcare Systems and Reforms
- Liver Disease Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Antibiotic Use and Resistance
- Health Systems, Economic Evaluations, Quality of Life
- HIV/AIDS drug development and treatment
- Child and Adolescent Health
- Cancer Risks and Factors
- Birth, Development, and Health
- Cervical Cancer and HPV Research
- Health Promotion and Cardiovascular Prevention
- Economic and Financial Impacts of Cancer
- Obesity, Physical Activity, Diet
- Mental Health Treatment and Access
- Healthcare cost, quality, practices
- Climate Change and Health Impacts
- Blood groups and transfusion
UNSW Sydney
2017-2024
World Health Organization
2024
World Health Organization Regional Office for South-East Asia
2013-2022
Organisation de Coopération et de Développement Economiques
2013-2022
Médecins Sans Frontières
2014
Point-of-care hepatitis C virus (HCV) RNA testing is advantageous, enabling diagnosis of active infection in a single visit. This study evaluated the sensitivity and specificity Xpert HCV Viral Load Finger-Stick assay (Xpert VL FS) for detection (finger-stick) (plasma) compared with Abbott RealTime by venepuncture. Plasma finger-stick capillary whole-blood samples were collected from participants an observational cohort Australia. Of 223 enrolled, was detected 40% (85 210) available testing....
People who inject drugs (PWID) are a priority population in HCV elimination programming. Overcoming sex and gender disparities risk, prevention, the cascade of care is likely to be important achieving this goal, but these have not yet been comprehensively reviewed.
Abstract Gaps in hepatitis C virus (HCV) testing, diagnosis, liver disease assessment and treatment uptake among people who inject drugs (PWID) persist. We aimed to describe the cascade of HCV care PWID Australia, prior following unrestricted access direct‐acting antiviral (DAA) treatment. Participants enrolled an observational cohort study between 2014 2018 provided fingerstick whole‐blood samples for dried blood spot, Xpert Viral Load venepuncture samples. underwent transient elastography...
People who are homeless have increased hepatitis C virus (HCV) infection risk, and less likely to access primary healthcare. We aimed evaluate HCV RNA prevalence, liver disease burden, linkage care treatment uptake outcomes among people attending a homelessness service in Sydney. Participants were enrolled an observational cohort study with recruitment at over eight health campaign days. Finger-stick whole-blood samples for Xpert® Viral Load venepuncture blood collected. completed...
Community pharmacists like other health care professionals in Lebanon have been grappling with a series of multifaceted, country-wide and ongoing challenges that formed the impetus for this research. We aimed to explore experiences community Beirut, Lebanon, during three concurrent crises 2020: Lebanese financial crisis, COVID-19 pandemic Beirut Port explosion.A qualitative approach using constructivist grounded theory methodology was employed. Between October 2020 February 2021,...
There is limited research on health-related quality of life (HRQoL) among people who inject drugs (PWID). We aimed to evaluate factors associated with HRQoL a cohort PWID in Australia.Participants were enrolled an observational study (the LiveRLife Study) between 2014 and 2018 at 15 sites Australia. They provided fingerstick whole-blood samples for point-of-care HCV RNA testing underwent transient elastography assess liver disease. Participants completed the EQ-5D-3L survey enrolment....
A district hospital in Kabul, Afghanistan, supported by Médecins Sans Frontières (MSF).To assess antibiotic prescribing practices the out-patient department summer (August 2013) and winter (January 2014).Cross-sectional study, using routinely collected data World Health Organization (WHO) defined daily dose (DDD) methodology.An analysis of 4857 prescriptions (summer) 4821 (winter) showed that respectively 62% 50% all out-patients were prescribed at least one antibiotic. Prescriptions without...
The global scale-up of hepatitis C virus (HCV) diagnosis requires simplified and affordable HCV diagnostic pathways. This study evaluated the sensitivity specificity Architect core antigen (HCVcAg) assay for detection active infection in plasma capillary whole blood dried spots (DBS) compared with RNA testing (Abbott RealTime Viral Load). Samples were collected from participants an observational cohort enrolled at three sites Australia (two-drug treatment alcohol clinics one homelessness...
People who inject drugs are at greater risk of hepatitis C virus (HCV) infection and hospitalization, yet admissions not utilized for HCV treatment initiation. We aimed to assess the extent which people with notification, including those evidence recent drug dependence, hospitalized while eligible direct-acting antiviral (DAA) therapy, uptake according hospitalization in DAA era.We conducted a longitudinal, population-based cohort study living era (March 2016-December 2018) through analysis...
Simplified diagnostic strategies are needed increase hepatitis C virus (HCV) testing to determine active infection and link people into treatment. Collection methods such as dried blood spots (DBS) have advantages over standard phlebotomy, especially within marginalized populations.We evaluated the performance of Aptima HCV Quant assay for quantification detection RNA from paired DBS venepuncture samples. Specimens were collected participants enrolled in an Australian observational study. We...