A5025790604- Advanced Aircraft Design and Technologies
- Free Radicals and Antioxidants
- bioluminescence and chemiluminescence research
- Engineering and Materials Science Studies
- Computational Fluid Dynamics and Aerodynamics
- Structural Analysis of Composite Materials
- Estrogen and related hormone effects
- Civil and Structural Engineering Research
- Interactive and Immersive Displays
- Air Traffic Management and Optimization
- Congenital Heart Disease Studies
- Radiation Effects and Dosimetry
- Dialysis and Renal Disease Management
- Artificial Intelligence in Games
- Usability and User Interface Design
- Microfluidic and Bio-sensing Technologies
- Vehicle emissions and performance
- Hemophilia Treatment and Research
- Photochemistry and Electron Transfer Studies
- Metal Forming Simulation Techniques
- Aerospace Engineering and Energy Systems
- Phytoestrogen effects and research
- Fatigue and fracture mechanics
- Innovative Human-Technology Interaction
- T-cell and B-cell Immunology
Technical University of Darmstadt
1999-2022
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2017-2022
University of Oxford
2022
University Hospital Frankfurt
2018-2019
Goethe University Frankfurt
2018-2019
Virtual Vehicle (Austria)
2012-2018
University of Tübingen
2012-2017
Bauhaus-Universität Weimar
2015-2016
University of Vienna
1999-2015
Virtuelle Fabrik (Switzerland)
2014
We have tested the hypothesis that elevated concentrations of TNF alpha could impair trophoblast invasion. Using first-trimester placental explant cultures, we demonstrated cytokine inhibits in vitro migration extravillous trophoblasts (EVT) on collagen I, and invasion through Matrigel. To elucidate underlying mechanism, proliferation differentiation EVT were analyzed by immunohistochemistry serial sections, Western blotting, zymography, ELISA, RT-PCR from RNA pools mechanically separated...
A method to manipulate and control droplets on a surface is presented. The based inducing electric dipoles inside the using homogeneous external field. It shown that repulsive dipole force efficiently suppresses coalescence of moving liquid-infused (LIS). Using combination experiments, numerical computations semi-analytical models, dependence repulsion droplet volumes, distance between field strength revealed. allows suppress in complex multi-droplet flows real-time adaptive. When exceeds...
One of aviation’s major challenges for the upcoming decades is reduction in its climate impact. As synthetic kerosene and green hydrogen are two promising candidates, their potentials decreasing impact investigated mid-range segment. Evolutionary advancements 2040 applied, first with an conventional second advanced low-NOx low-soot combustion chamber. Experts methods from all relevant disciplines involved, starting combustion, turbofan engine, overall aircraft design, fleet level,...
We present Shoe me the Way, a novel tactile interface for eyes-free pedestrian navigation in urban environments. Our prototypical implementation can be fully integrated into users' own, regular shoes without permanent modifications. Interface use does not distract users from their surroundings. It thereby adds to safety and enables them explore environments more freely than is possible with prevailing mobile map-based systems. evaluated our prototype using two different modes study 21...
Objective To develop an NIH Stroke Scale (NIHSS)-compatible, all-in-one scale for rapid and comprehensive prehospital stroke assessment including recognition, severity grading progression monitoring as well prediction of large vessel occlusion (LVO). Methods Emergency medical services (EMS) personnel physicians (n=326) rated each item the NIHSS regarding suitability use; best items were included. recognition was evaluated retrospectively in 689 consecutive patients with acute or mimics, LVO...
We optimized an RIA for measurement of arginine8-vasopressin (AVP) in plasma by use 100-mg Isolute C18 columns extraction, addition a preincubation step, and maximal dilution commercially available antiserum. The detection limit was 0.06 ng/L when 0.5 mL acidified extracted. within- between-run CVs (n = 16) at physiological concentrations were 5.8-10. 2% 6.5-11.7%, respectively. Prolonged storage blood 25 degreesC, but not 4 led to significant increase measured AVP concentrations. When...
PURPOSE: To evaluate phase-contrast magnetic resonance (MR) imaging for sizing of secundum atrial septal defects (ASDs) and inflow MR angiography detection associated venous anomalies in pediatric patients with inconclusive transthoracic echocardiographic (TTE) results. MATERIALS AND METHODS: Sixty-five children (mean age, 5.4 years ± 2.7 [SD]) ASD TTE results underwent imaging. Defect size rim distances measured on sections obtained the plane from defect to venae cavae, aortic root,...
Background Right ventricular outflow tract (RVOT) stenosis after repair of tetralogy Fallot has been linked with favorable right remodeling but adverse outcomes. The aim our study was to assess the hemodynamic impact and prognostic relevance pressure load in this population. Methods Results A total 296 patients repaired (mean age, 17.8±7.9 years) were included a prospective cardiovascular magnetic resonance multicenter study. Myocardial strain quantified by feature tracking technique at...
The DLR project VicToria brings together disciplinary methods and tools of different fidelity for collaborative multidisciplinary design optimization (MDO) long-range passenger aircraft configurations, necessitating the use high-performance computing. Three approaches are being followed to master complex interactions disciplines software aspects: an integrated aero-structural wing based on high-fidelity methods, a multi-fidelity gradient-based approach capable efficiently dealing with many...
The phase transition and distribution in an all-aqueous sessile drop containing polyethylene glycol (PEG) dextran is studied. Evaporation of water triggers the formation dextran-rich droplets close to contact line that subsequently migrate towards center. likely reason for droplet migration Marangoni convection due stresses at interface between surrounding liquid.
Over the past decade, profound attention was given to exploring benefits of engaging numerical multidisciplinary design optimization in aircraft design. Due its importance, aerostructural wing is most visited problem research institutes. To deal with this efficiently, gradient-based algorithms are popularly used. The complexity optimization, however, forced researchers apply several simplifications formulation, such as neglecting engine effects or oversimplifying loads process into few...
Based on the previous results concerning electron transfer processes in biological substances, it was of interest to investigate if hormone transients resulting by e.g. emission can be regenerated.The presented prove for first time that originating process successfully regenerated electrons from a potent donor, such as vitamin C (VitC). Investigations were performed using progesterone (PRG), testosterone (TES) and estrone (E1) representatives hormones. By irradiation with monochromatic UV...
The concentration patterns of DNA molecules attached to the interface between two immiscible aqueous phases forming under an electric field are studied. pattern formation is driven by hydrodynamic interactions originating from electro-osmotic flow due Debye layer around a molecule. A nonlinear integrodifferential equation derived describing time evolution at liquid-liquid interface. linear stability analysis this shows that mode given wavelength initially stable, but destabilizes after...
In this paper, we present the Massive Mobile Multiuser (M3) framework, a software platform designed to enable setup-free, real-time, concurrent interaction with shared public displays through large numbers of personal mobile devices. This work is motivated by fact that simultaneous multiple persons requires either dedicated tracking hardware detect gestures or touch, way for users interact their The latter option provides more flexibility but also presents heightened entry barrier as it...
Electric-field driven transition of proteins between two aqueous phases at the liquid–liquid–solid contact line.
The aviation sector is facing serious challenges to achieve the environmental goals set up by FlightPath2050 and cope with changing behavior of society political decisions. Besides gradually increasing efficiencies air vehicles, these can be managed implementing alternative energy carriers into transport system. carrier itself has a tremendous impact on propulsion architecture vehicle related technology options. After preselection, four promising for future sustainable are investigated...