- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Conditions and Treatments
- Thermal Regulation in Medicine
- Mechanical Circulatory Support Devices
RWTH Aachen University
2022-2025
Ruhr University Bochum
2018-2022
Heart and Diabetes Center North Rhine-Westphalia
2018-2022
Universitätsklinikum Aachen
2020
Abstract Background and Aims Landiolol, an ultra-fast acting super-selective beta-blocker, was investigated for the first time in Europe a prospective clinical study management of supraventricular tachycardia (SVT) among paediatric patients. Methods LANDI-PED prospective, multicentre, open-label, uncontrolled phase III aiming to investigate efficacy, safety, pharmacokinetics (PK) landiolol 60 patients surgical non-surgical settings aged ≥1 day <18 years with SVTs various aetiologies...
Background Right ventricular outflow tract (RVOT) stenosis after repair of tetralogy Fallot has been linked with favorable right remodeling but adverse outcomes. The aim our study was to assess the hemodynamic impact and prognostic relevance pressure load in this population. Methods Results A total 296 patients repaired (mean age, 17.8±7.9 years) were included a prospective cardiovascular magnetic resonance multicenter study. Myocardial strain quantified by feature tracking technique at...
Background: After encouraging results with the Edwards Sapien and XT valves, this study aimed to review procedural data early outcomes for 3 valves transcatheter pulmonary valve replacement (TPVR). Methods: We performed a multicenter, retrospective analysis of cases who underwent TPVR between 2015 2017 in 7 centers Germany follow-up up 2 years. Results: 56 patients could be enrolled (weight 58,5 ± 25,0 kg; 53% Tetralogy Fallot, 45% native RVOT). Most procedures were two-stage (82,1%) 100%...
Abstract To assess the efficacy and safety of a breakable BabyStent to treat complex aortic coarctation (CoA) in early childhood. Although recommended several guidelines, there is no approved stent for young infants, because dilemma between two mandatory requirements: expandable up adult size on one hand, small enough fit through baby's femoral artery other. Prospective interventional, multi‐center clinical trial with Osypka BabyStent® (OBS). The OBS low‐profile, 15‐mm long cobalt‐chromium...