A5053701309- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular and Diving-Related Complications
- Ion channel regulation and function
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Congenital heart defects research
- Neonatal Respiratory Health Research
- Cardiac Fibrosis and Remodeling
- Cardiac Arrest and Resuscitation
- Tracheal and airway disorders
- Mechanical Circulatory Support Devices
- Pericarditis and Cardiac Tamponade
- Coronary Artery Anomalies
- Systemic Lupus Erythematosus Research
- Pectus Deformity Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Cardiac tumors and thrombi
Westpfalz Klinikum
2015-2025
Justus-Liebig-Universität Gießen
2009-2019
German Red Cross
2019
University of Göttingen
2005-2018
Universitätsmedizin Göttingen
2011-2018
University of Kaiserslautern
2015
Klinik und Poliklinik für Kinder- und Jugendmedizin
2014
Deutsches Herzzentrum München
2009
Medizinische Hochschule Hannover
2000-2006
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge, evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
The population of patients with congenital heart disease (CHD) is continuously increasing more and reaching adulthood. A significant portion these young adults will suffer from arrhythmias due to the underlying defect itself or as a sequela interventional surgical treatment. medical community encounter an challenge even most individuals complex defects nowadays become adults. Within past 20 years, management has gained remarkable progress including pharmacological treatment, catheter...
[2015 ESC Guidelines for the management of patients with ventricular arrhythmias and prevention sudden cardiac Death. The Task Force Management Patients Ventricular Arrhythmias Prevention Sudden Cardiac Death European Society Cardiology].
Abstract Background and Aims Landiolol, an ultra-fast acting super-selective beta-blocker, was investigated for the first time in Europe a prospective clinical study management of supraventricular tachycardia (SVT) among paediatric patients. Methods LANDI-PED prospective, multicentre, open-label, uncontrolled phase III aiming to investigate efficacy, safety, pharmacokinetics (PK) landiolol 60 patients surgical non-surgical settings aged ≥1 day <18 years with SVTs various aetiologies...
Introduction: Cryoenergy has evolved as a safe and effective alternative for ablation of arrhythmia substrates in adult patients. Due to two specific features, cryomapping cryoadhesion, this technique appears very attractive pediatric patients minimizing complications fluoroscopy time. The aim the study was investigate efficacy safety cryoenergy supraventricular tachycardia (SVT) Patients Methods: Thirty‐two (mean age: 10.1 ± 3.5 years) with SVT (accessory pathways: n = 19; atrioventricular...
Left cardiac sympathetic denervation (LCSD) may be a therapeutic adjunct for young patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) and long QT syndrome (LQTS) who are not fully protected by beta-blockade.The objective of this analysis was to report our institutional experience LSCD in the management life-threatening arrhythmias CPVT LQTS.Ten LQTS underwent transaxillary at institution. Mean age surgery 14.0 (range 3.9-42) years, mean body weight 45.7 15.5-90) kg....
Catheter ablation of the slow conducting pathway (SP) is treatment choice for atrioventricular nodal reentrant tachycardia (AVNRT). Although there are abundant data on AVNRT in adult patients, little known about long-term results ≥3 years after pediatric patients.Follow-up from 241 patients aged ≤18 who had undergone successful were analyzed. Median age at been 12.5 years, and median follow-up was 5.9 years. Radiofrequency current used 168 (70%), whereas cryoenergy 73 (30%). Procedural end...
The purpose of the present study was to determine role a novel, noncontact mapping system for assessing variety atrial reentrant tachycardias (ART) in patients after surgical correction congenital heart disease.In 14 patients, an electrophysiological using Ensite 3000 performed assess ARTs resistant medical treatment. Sixteen different forms ART were inducible studied. circuit all could be characterized and localized with respect anatomic landmarks such as atriotomy scars, intraatrial...
We sought to evaluate tissue reactions within and at the surface of devices for interventional therapy septal defects identify antigen characteristics neotissues.Atrial or ventricular defect-occlusion (Amplatzer, n=7; Cardioseal/Starflex, n=3) were processed using a uniform protocol after surgical removal from humans (implantation time, 5 days 4 years). Devices fixed in formalin embedded methylmethacrylate. Serial sections obtained by sectioning with diamond cutter grinding, thus saving...
Abstract Drowning and near‐drowning is often associated with severe hypothermia requiring active core rewarming. We performed rewarming by cardiopulmonary bypass (CPB). Between 1987 2007, 13 children (9 boys 4 girls) accidental were rewarmed extracorporeal circulation (ECC) in our institution. The average age of the patients was 3.2 years. Resuscitation started immediately upon arrival rescue team continuously during transportation. All intubated ventilated. Core temperature at admission...
There is no clear methodology for implantation of an internal cardioverter-defibrillator (ICD) in infants and small children. The aim this study was to assess efficacy safety extracardiac ICD technique pediatric patients.An system implanted eight patients (age: 0.3-8 years; body weight: 4-29 kg). Under fluoroscopic guidance a defibrillator lead tunneled subcutaneously starting from the anterior axillar line along course 6th rib until almost reaching vertebral column. After partial inferior...
Background: Animal studies and clinical observations have demonstrated that radiofrequency current application at growing myocardium may result in coronary artery obstruction. Recently, cryoenergy has emerged as an effective alternative to ablation of arrhythmogenic substrates pediatric patients. Up now, there been a lack experimental data concerning the effects myocardium. Methods: During general anesthesia, selective angiography right left was performed 10 piglets (age: 6 weeks, body...
Data on closure of atrial septal defects (ASD) in elderly patients with a fenestrated Amplatzer occluder (ASO) device is limited.A hemodynamically significant ASD was closed ASO 3 ages >62 years. Prior to implant 4-mm fenestration created by balloon dilatation without additional suture fixation just adjacent the stent part device. Indications for were restrictive left ventricular physiology and/or pulmonary hypertension. Heparin had been administered during and 48 hours after procedure. Two...