A5085206294- Migraine and Headache Studies
- Cervical Cancer and HPV Research
- Autism Spectrum Disorder Research
- Animal Genetics and Reproduction
- Neurological Disorders and Treatments
- Psoriasis: Treatment and Pathogenesis
- T-cell and Retrovirus Studies
- Nutrition, Genetics, and Disease
- Digestive system and related health
- Ubiquitin and proteasome pathways
- RNA and protein synthesis mechanisms
- Animal Disease Management and Epidemiology
- Biomedical Text Mining and Ontologies
- Computational Drug Discovery Methods
- Genetic and phenotypic traits in livestock
- RNA Research and Splicing
- Cerebrovascular and genetic disorders
- Bioinformatics and Genomic Networks
- Genomics and Chromatin Dynamics
- Biochemical effects in animals
- Molecular Biology Techniques and Applications
- Chromosomal and Genetic Variations
- Epigenetics and DNA Methylation
- Anesthesia and Sedative Agents
- Animal Nutrition and Health
Lomonosov Moscow State University
2013-2022
Moscow State University
2012-2022
Sirius University of Science and Technology
2020
Consultative and Diagnostic Center
2016-2019
Russian Academy of Sciences
2002-2019
Institute of Higher Nervous Activity and Neurophysiology
2019
Vavilov Institute of General Genetics
2001-2017
Sechenov University
2016
Research Center of Neurology
2016
DNA Diagnostic (Denmark)
2016
It was previously shown that the MTHFR gene polymorphism correlated with an increased risk of migraine, particularly migraine aura. The substitution cytosine for thymine at position 677 leads to formation thermolabile form protein and development hyperhomocysteinemia, which increases probability migraine. purpose this study determine whether replacement C677T in influenced any particular symptoms disease.We have analyzed clinical electrophysiological characteristics 83 patients (migraine...
Homozygous deletions or loss of heterozygosity (LOH) at human chromosome band 3p12 are consistent features lung and other malignancies, suggesting the presence a tumor suppressor gene(s) (TSG) this location. Only one gene has been cloned thus far from overlapping region deleted in breast cancer cell lines U2020, NCI H2198, HCC38. It is DUTT1 (Deleted U Twenty Twenty), also known as ROBO1, FLJ21882, SAX3, according to HUGO. DUTT1, ortholog fly ROBO, homology with NCAM proteins. Extensive...
In cervical tumours the integration of human papilloma viruses (HPV) transcripts often results in generation that consist hybrids viral and cellular sequences. Mapping data using a variety techniques has demonstrated HPV occurred without obvious specificity into genome. However, these could not demonstrate whether resulted encoding or viral-cellular The aim this work was to map sites DNA analyse adjacent Amplification INTs done by APOT technique. products were sequenced according standard...
Impulsive-compulsive and related behavioral disorders (ICD) are drug-induced non-motor symptoms of Parkinson's disease (PD). Recently research has focused on evaluating whether ICD could be predicted managed using a pharmacogenetic approach based dopaminergic therapies, which the main risk factors. The aim our study was to evaluate role candidate genes such as DBH, DRD2, MAOA, BDNF, COMT, SLC6A4, SLC6A3, ACE, DRD1 gene polymorphisms in pathogenesis PD. We compared patients with PD (n = 49),...
ОБЗОР ВАРИАБЕЛЬНОСТИ ГЕНОВ, СВЯЗАННЫХ С МОЛОЧНОЙ ПРОДУКТИВНОСТЬЮ КРУПНОГО РОГАТОГО СКОТА1,2 Шевцова А
Sequence tagged sites generated for 60 <i>Not</i>I clones (<i>Not</i>I-STSs) from human chromosome 3-specific <i>Not</i>I-jumping and <i>Not</i>I-linking libraries were physically located using PCR screening of a radiation hybrid (RH) GeneBridge4 panel. The map 3 was these RH-mapping data those obtained earlier by FISH sequencing the corresponding clones. sequences showed significant homologies with known genes and/or ESTs 58...
This article describes premises for the development of psychodermatology. An analysis research literature and data is presented based on example psoriasis anxiety disorder. Protein molecules with altered concentrations in patients disorder compared to controls are identified (chemokine [C-C motif] ligand 2, corticotropin-release hormone, growth hormone 1, leptin, tumor necrosis factor increased concentration brain-derived neurotrophic decreased concentration). All secretory peptides. In...
Aims: Alice-in-Wonderland syndrome (AIWS) is a rare neuropsychological that includes paroxysmal distortion of the body schema, depersonalization, derealization, visual hallucinations, distorted sense time, and deja vu jamais experiences. may be an equivalent migraine attack. The objective this study was to evaluate clinical particulars in patients suffering from migraine. Place Duration Study: University Headache Clinic between June 2012 November 2015. Methodology: sample involved 14...
Using a new pEnLox vector employed to generate gain-of-function mutants in Arabidopsis thaliana, the AtFAS4 mutant has been obtained and analyzed. The is characterized by super-expression of At1g33390 gene, which leads occurrence phenotype - stem fasciation. level expression gene normally developing A.thaliana plants extremely low thus accounting for almost complete absence information on EST's this gene. generated permitted full-length cDNA be analyzed first time.
Methylation of promoter CpG islands and microRNA (miRNA) interactions with mRNAs target genes are epigenetic mechanisms that play a crucial role in deregulation gene expression signaling pathways tumors. Altered six chromosome 3p (RARB(2), SEMA3B, RHOA, GPX1, NKIRAS1, CHL1) two miRNA (MIR-129-2 MIR-9-1) was observed primary clear cell renal carcinomas (ccRCCs, 31-48 samples) by RT-PCR qPCR. Significant downregulation (p < 0.05, Fisher's exact test) for CHL1; differential expression, the...