A5078159501- MicroRNA in disease regulation
- Circular RNAs in diseases
- Dental Implant Techniques and Outcomes
- Retinal Development and Disorders
- Pluripotent Stem Cells Research
- Osteoarthritis Treatment and Mechanisms
- Cancer-related molecular mechanisms research
- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- High Entropy Alloys Studies
- Bone Tissue Engineering Materials
- Anesthesia and Neurotoxicity Research
Gansu Agricultural University
2024-2025
Qingdao University
2020-2022
Systematic administration of anti-inflammatory cytokine interleukin 4 (IL-4) has been shown to improve recovery after cerebral ischemic stroke. However, whether IL-4 affects neuronal excitability and how improves injury remain largely unknown. Here we report the neuroprotective role endogenous in focal ischemia–reperfusion (I/R) injury. In multi-electrode array (MEA) recordings, reduces spontaneous firings network activities mouse primary cortical neurons. mRNA protein expressions are...
The repair of osteochondral defects is one the major clinical challenges in orthopaedics. Well-established tissue engineering methods have shown promising results for early treatment small defects. However, less success has been achieved regeneration large defects, which mainly due to mechanical environment joint and heterogeneous nature tissue. In this study, we developed a multi-layered scaffold match by harnessing additive manufacturing technologies combining established art laser...
MicroRNAs (miRNAs) are short endogenous non-coding RNAs and play important roles in regulating mammary development activities of ovine epithelial cells (OMECs), which affect the milk yield ingredient contents ewes. We previously found that miR-21 was highly expressed tissue, while regulatory mechanisms underlying lactation performance still unclear. Accordingly, this study, we investigated functions OMECs, validated target relationship with a predicted gene programmed cell death 4 (PDCD4) by...
The proliferation and differentiation of skeletal muscle satellite cells (SMSCs) are responsible for the development muscle. In our previous study, circ_002156 was found to be highly expressed in caprine Longissimus Dorsi muscle, but regulatory role circular RNAs (circRNA) goat SMSCs remains unclear. this authenticity validated, its structurally characteristic cellular localization as well tissue expression parent genes were investigated. Moreover, effects on viability, proliferation, also...