A5035462540- Cancer, Lipids, and Metabolism
- Nutrition, Genetics, and Disease
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Cardiac tumors and thrombi
- MicroRNA in disease regulation
- Lung Cancer Research Studies
- Teratomas and Epidermoid Cysts
- Testicular diseases and treatments
- Circular RNAs in diseases
- Nuclear Receptors and Signaling
- Neuroblastoma Research and Treatments
Kunming Medical University
2022-2024
Innovation Team (China)
2022-2023
Guizhou Provincial People's Hospital
2022
Guizhou University
2022
Abstract Background The prognostic management of bladder cancer (BLCA) remains a great challenge for clinicians. Recently, bulk RNA-seq sequencing data have been used as marker many cancers but do not accurately detect core cellular and molecular functions in tumor cells. In the current study, single-cell RNA (scRNA-seq) were combined to construct model BLCA. Methods BLCA scRNA-seq downloaded from Gene Expression Omnibus (GEO) database. Bulk obtained UCSC Xena. R package "Seurat" was...
Background: Numerous types of research revealed that long noncoding RNAs (lncRNAs) played a significant role in immune response and the tumor microenvironment bladder cancer (BLCA). Dysregulated lipid metabolism is considered to be one major risk factors for BLCA, study aimed detect metabolism-related lncRNAs (LMRLs) along with their potential prognostic values correlations BLCA. Methods: We collected genes, expression profiles, clinical information on BLCA from Molecular Signature Database...
Prostate cancer (PCa) is among the three main types of cancer. Although prostate-specific antigen (PSA) routinely tested, it has disadvantages, such as poor prognostic ability. Therefore, finding more PCa markers and therapeutic targets remains a subject study. CircRNAs have been found to regulatory roles in various diseases, diabetes, Central Nervous System (CNS) neuropathy, etc. where their application even valuable. this paper aims search for differentially expressed circRNAs find...
Background. Bladder cancer (BLCA) is a highly malignant tumor that develops in the urinary system. Identification of biomarkers progression and prognosis crucial for treatment BLCA. BLCA-related differentially expressed genes (DEGs) were authenticated by screening DEGs weighted gene coexpression network analysis (WGCNA). LASSO SVM-RFE algorithms utilized to screen feature Survival was performed using Kaplan-Meier curve provided 'survival' R package. The BLCA samples clustered hclust based on...
Abstract Background Bladder cancer (BC) is the most common genitourinary malignancy worldwide, and its aetiology pathogenesis remain unclear. Long noncoding RNAs can play vital roles in gene expression diverse biological processes, especially cancers. Accumulating evidence has shown that HAGLROS, a novel lncRNA, closely related to occurrence progression of various However, functions underlying mechanisms HAGLROS BC unknown. Methods The relative was determined by bioinformatics analysis,...