Libo Yang

ORCID: 0000-0003-3791-1505
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About
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • MicroRNA in disease regulation
  • Platelet Disorders and Treatments
  • Gastrointestinal motility and disorders
  • Gastric Cancer Management and Outcomes
  • Geophysical and Geoelectrical Methods
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Gas Sensing Nanomaterials and Sensors
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Erythrocyte Function and Pathophysiology
  • Radioactive element chemistry and processing
  • Seismic Imaging and Inversion Techniques
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Cancer, Lipids, and Metabolism
  • Advanced Photocatalysis Techniques
  • Long-Term Effects of COVID-19
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Circular RNAs in diseases
  • Crystallography and molecular interactions
  • Rheology and Fluid Dynamics Studies
  • Advanced Polymer Synthesis and Characterization
  • Sphingolipid Metabolism and Signaling

Guangxi University
2023-2025

Life Cycle Engineering (United States)
2025

Peking University
2024

Kunming Medical University
2017-2024

Peking University Cancer Hospital
2024

Taian City Central Hospital
2024

Qingdao University
2024

First People's Hospital of Yunnan Province
2013-2022

Kunming University of Science and Technology
2017-2022

Ocean University of China
2021

We examined the sphingolipid metabolism of peripheral blood cells, i. e. platelets, erythrocytes, neutrophils and mononuclear cells. A distinguishing characteristic in these highly differentiated cells was their high sphingosine (Sph) kinase activity. The occurrence [3H]sphingosine 1-phosphate (Sph-1-P) from [3H]Sph (actively incorporated outside) strong, long-lasting, independent cell activation. Hence, possibility Sph-1-P playing a second messenger role is remote About 40% platelet could...

10.1046/j.1365-2141.1999.01697.x article EN British Journal of Haematology 1999-11-01

Gastric cancer is the fourth most common malignant disease and second leading cause of cancer‑associated mortalities worldwide. Previous studies revealed aberrantly expressed microRNAs (miRNAs) in various types human cancer; these miRNAs play important roles tumourigenesis tumour development. present a considerable potential for novel therapeutic approaches treating cancer. Therefore, investigation involved gastric progression provides an opportunity to improve prognosis patients with...

10.3892/mmr.2017.8299 article EN Molecular Medicine Reports 2017-12-18

The aetiology of bone metastasis in prostate cancer (PCa) remains unclear. This study aims to identify hub genes involved this process. We utilized machine learning, GO, KEGG, GSEA, Single-cell analysis, ROC methods for PCa using the TCGA and GEO databases. Potential drugs targeting these were identified. validated results 16 specimens from patients with analysed relationship between clinical features. impact APOC1 on was assessed through vitro experiments. Seven AUC values 0.727-0.926...

10.1111/jcmm.18511 article EN cc-by Journal of Cellular and Molecular Medicine 2024-08-01

Abstract Downhole dynamics and mechanics data have been acquired during drilling operations for at least forty years, but beyond simple shock counts stick-slip estimation are still not routinely used to aid the driller either in real-time control of process or post-well analysis. The barriers doing this include equipment cost reliability, telemetry bandwidth from downhole surface, availability expertise interpretation. In paper it is shown how valuable information can be using accelerometers...

10.2118/223712-ms article EN SPE/IADC International Drilling Conference and Exhibition 2025-02-25

Abstract A novel low-cost MWD provides data for integration with a new cloud-based rig architecture. The and advanced algorithms in the system improve both rate reliability, making it suitable source of data. integrated architecture combines an edge platform at accessible through unified interface. This enables deployment drilling automation analytics to operational performance. also supports machine learning models be trained cloud across regional deploy them edge, quickly efficiently....

10.2118/223714-ms article EN SPE/IADC International Drilling Conference and Exhibition 2025-02-25

Wolframite (FeWO4) is a type of polyoxometalate known for its high chemical stability and electronic properties, which makes it an excellent photocatalyst. While FeWO4 has been widely utilized in the domain organic catalysis, there are currently no documented reports regarding use degradation U(VI). In this study, effect changing microscopic morphology catalyst to enhance photocatalytic activity was explored. We effectively adjusted microstructure crystallinity by varying hydrothermal...

10.1021/acs.langmuir.4c05301 article EN Langmuir 2025-03-14

The study was aimed to investigate the effect of baicalein, a flavonoid molecule isolated from plant Oroxylum indicum on bladder cancer cell viability. results revealed that baicalein treatment T24 and 253J cells targeted expression mRNA proteins corresponding anti-apoptotic genes. RT-PCR assay showed genes were markedly over-expressed in cells. Exposure at 5 mg/mL doses for 72 h led reduction levels antiapoptotic In cells, BCL2, Bcl-xL, XIAP surviving reduced by 65, 69, 58 72%,...

10.1016/j.sjbs.2017.03.014 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2017-03-29
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