A5102897938- Head and Neck Cancer Studies
- Breast Cancer Treatment Studies
- Head and Neck Surgical Oncology
- Breast Lesions and Carcinomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gestational Diabetes Research and Management
- Global Cancer Incidence and Screening
- Advanced Radiotherapy Techniques
- Bariatric Surgery and Outcomes
- Effects of Radiation Exposure
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Antifungal resistance and susceptibility
- AI in cancer detection
- Cancer Genomics and Diagnostics
- Cancer Treatment and Pharmacology
- Obesity and Health Practices
- Anesthesia and Neurotoxicity Research
- Diet and metabolism studies
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Diet, Metabolism, and Disease
- Viral-associated cancers and disorders
- Colorectal and Anal Carcinomas
- Anesthesia and Sedative Agents
Sun Yat-sen University
2015-2024
Sun Yat-sen Memorial Hospital
2017-2024
State Key Laboratory of Food Science and Technology
2024
Jiangnan University
2024
Zhongshan Hospital of Xiamen University
2024
Xiamen University
2024
Fujian Provincial Hospital
2024
School for Ethical Education
2019
State Key Laboratory of Oncology in South China
2015-2017
Sun Yat-sen University Cancer Center
2015-2017
This study aimed to evaluate the efficacy of concurrent chemoradiotherapy (CCRT) for stage II nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiation therapy (IMRT). A total 249 were retrospectively reviewed. All IMRT. One hundred forty-three CCRT and 106 IMRT alone. With a median follow-up 59.4 months, adding chemotherapy did not statistically significantly improve 5-year overall survival (OS) (89.7 % vs 99.0 %, p = 0.278), locoregional relapse-free (LRFS) (94.8...
Background: Tangential irradiation is the most popular postoperative radiotherapy technique for breast cancer. However, has been related to symptomatic radiation pneumonitis (SRP), which decreases quality of life patients. This study investigated clinical features and dosimetric parameters SRP ipsilateral lung identify risk factors in cancer patients after three-dimensional conformal therapy (3D-CRT) with tangential fields. Material Methods: A total 515 were evaluated divided into two...
Our objective was to examine whether adding induction chemotherapy concurrent chemoradiotherapy improved survival in stage III nasopharyngeal carcinoma (NPC) patients, especially low-risk patients at T3N0-1.We retrospectively analyzed 687 with T3N0-1 NPC treated intensity-modulated radiation therapy (IMRT) plus (CC) or without (IC). Propensity score matching (PSM) method used select 237 pairs of from two cohorts. Overall (OS), locoregional relapse-free (LRFS), distant metastasis-free (DMFS),...
We aimed to validate and compare the 7th 8th edition of AJCC staging systems for non-metastatic nasopharyngeal carcinoma, proposed from Hong Kong, Guangzhou, Guangxi.We retrospectively included 899 patients treated between November 5, 2002 May 27, 2010. Separation discrimination each system in overall survival were primarily compared.Compared with AJCC, all well separated across T-classification. T-classification Guangzhou seemed perform best (C-index 0.6454), followed by (0.6451), (0.6386),...
The effect of taxanes-based induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (LA-NPC) was quite contradictory two phase II randomized controlled trials with small sample size. We aimed to investigate it this large scale propensity-matched study.Totally, 779 LA-NPC patients who underwent intensity-modulated radiotherapy (IMRT) plus concurrent or without IC were included. Patients both treatment arms matched using propensity score matching method at the ratio...
Leucopenia or neutropenia during chemotherapy predicts better survival in several cancers. We aimed to assess whether leucopenia could be a biological measure of treatment and marker efficacy advanced nasopharyngeal carcinoma (ANPC). retrospectively analyzed 3826 patients with ANPC who received chemoradiotherapy. was categorised on the basis worst grade according National Cancer Institute Common Toxicity Criteria version 4.0: no (grade 0), mild 1–2), severe 3–4). Associations between were...
Due to the low incidence of pretreatment anemia in nasopharyngeal carcinoma (NPC), true prognostic impact may be underestimated before. We retrospectively analyzed association with disease-specific survival (DSS), distant-metastasis-free (DMFS), and locoregional-relapse-free (LRFS) by Cox regression a cohort 5830 patients, stratifying midtreatment anemia, smoking, body mass index (BMI), etc. Pretreatment was significantly associated adverse DSS (hazard ratio (HR) = 2.15, 95 % confidence...
To develop a nomogram for predicting the possibility of four or more positive nodes in breast cancer patients with 1-3 sentinel lymph (SLN).Retrospective analysis data from two institutions was conducted. The inclusion criteria were: invasive cancer; clinically node negative; received lumpectomy mastectomy plus SLN biopsy followed by axillary dissection (ALND); and pathologically confirmed T1-2 tumor, SLNs. Patients one institution formed training group other validation group. Univariate...
Background: Literature pertaining to prophylactic inguinal nodal treatment for anal adenocarcinoma in China is scarce.Methods: In this retrospective study, we analyzed 126 patients from 1965 2015.Among these, 67 received surgery only, 18 chemoradiotherapy 27 a combination of both, and the remaining 14 palliative treatment.Results: The median follow up period was 30 months.The 1-year, 3-year, 5-year overall survival rates were 85.8%, 62.5%, 43.4%, respectively.The 46.9% with negative lymph...
There have been many reports on the prevalence and incidence of age-related macular degeneration (AMD), there are some systematic reviews reporting pooled AMD. However, is no review or progression AMD worldwide. Given few evidences regarding AMD, we performed this meta-analysis protocol to investigate global In addition, will risk factors for using meta-analysis.Four English databases (PubMed, EMBASE, Cochrane Library, Web Science) four Chinese (CMB, CNKI, VIP, Wanfang database) be searched...
Purpose The value of adding induction chemotherapy to chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (LA-NPC) remains controversial, yet high-risk patients with LA-NPC have poor outcomes after chemoradiotherapy. We aimed assess the survival benefits stage IVa-b NPC. Patients and Methods A total 602 NPC treated intensity-modulated radiation therapy (IMRT) concurrent or without were retrospectively analyzed. Overall (OS), locoregional relapse-free (LRFS), distant...
Postoperative radiotherapy (RT) can improve survival for T1-2N1 breast cancer. However, there exists a concern whether BCS plus RT has the same or superior therapeutic effect as that of mastectomy. In this study, we aimed to compare long-term results between after and postmastectomy in stage T1-2N1M0 cancer.Totally 1816 pathological cancer patients were analyzed. The propensity score matching (PSM) method was used select 196 pairs mastectomy receiving postoperative RT. Five-year locoregional...
Objective. This study aimed to identify clinicopathological factors related the extent of axillary lymph node (ALN) involvement in early-stage BC patients with positive sentinel nodes (SLNs). Methods. was a retrospective analysis 566 cT1-2N0M0 1-2 SLNs that underwent dissection (ALND) at Sun Yat-Sen Memorial Hospital. The clinical and pathologic data from these were analyzed. Results. Of patients, 235 (41.5%) exhibited NSLN metastases. Multivariate revealed number (odds ratio (OR) = 1.511;...
// Lu-Ning Zhang 1,2,* , Xing-Sheng Qiu 3,* Pu-Yun OuYang 2,* Yao Xiao 2 Xiao-Wen Lan Wuguo Deng Fang-Yun Xie and Xi-Cheng Wang 1 Department of Oncology, The First Affiliated Hospital Guangdong Pharmaceutical University, Guangzhou, China Sun Yat-sen University Cancer Center, State Key Laboratory Oncology in South China, Collaborative Innovation Center for Medicine, Guangdong, 3 Radiation Memorial Hospital, * Co-first authors Correspondence to: Wang, email: Xie, Deng, Keywords : age;...
HBV-infected individuals are also presenting with MASLD. However, the value of VCTE for detecting hepatic fibrosis and steatosis in CHB patients concurrent MASLD is unclear. In combined MASLD, we intend to assess diagnostic efficacy determining extent steatosis.
Postoperative radiotherapy in patients with breast cancer one to three lymph node metastases, particularly within the pT1-2N1M0 cohort a low clinical risk of local-regional recurrence (LRR), has incited discourse surrounding personalised treatment strategies. Multigene testing for Recurrence Index (RecurIndex) model capably differentiates based on their level LRR risk. This research aims validate whether more aggressive approach can enhance outcomes N1 who possess clinically LRR, yet high...
Nosocomial candidemia is a life-threatening condition, and the incidence has increased in recent years. Thorough epidemiological data still lacking China.
Objective To explore effects of the autonomic nervous system function on Intravenous injection lidocaine during intubation in patients with type 2 diabetes.Methods 70 undergoing abdominal surgery were randomly divided into group (group L,n=35,with intravenous 1.5 mg/kg lidocaine) and control C,n=35,with sodium chloride solution),The changes heart rate variability (HRV) recorded at following time points:prior to anesthesia (T0),1 min after induction (T1),3 prior (T2),1 (T3),the HRV was...
In the era of anti-HER2 targeted therapy, potential clinical feasibility considering HER2-overexpressing breast cancer cases presenting with 1-3 positive axillary lymph nodes as low-risk, and thereby contemplating postoperative radiotherapy reduction, remains an important subject for in-depth examination. The aim this retrospective study was to evaluate effectiveness de-escalated in T1-2N1M0 patients receiving therapy. Specifically, omitting regional node irradiation (RNI) after...
Objective To compare the clinical effects of target controlled intravenous anesthesia propofol combined with fentanyl or remifentanil and isoflurane.Methods 96 ASA Ⅰ-Ⅱ elective surgical patients from June 2010 to February 2012 were randomly divided into three groups 32 patients:propofol target-controlled group (group A),compound B),anesthesia C).Blood pressure,heart rate changes in induction maintenance observed recorded; spontaneous breathing recovery time,wake time,time...
Objective To access the clinical effect of medical radiation protective ointment compared with trolamine cream to prevent acute radiation-induced skin injury in breast cancer patients undergoing radiotherapy after modified radical mastectomy. Methods Between February 2017 and 2018, a total 120 stage T1-4N1-3M0 eligible received intensity modulated therapy were enrolled matches into two groups: study group (60 cases) was administered from first irradiation fraction, control cream. When...