Mark Appleyard

ORCID: 0000-0003-2714-8657
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Screening and Detection
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal disorders and treatments
  • Esophageal and GI Pathology
  • Genetic factors in colorectal cancer
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal Cancer Research and Treatment
  • Mycobacterium research and diagnosis
  • Diverticular Disease and Complications
  • Microscopic Colitis
  • Inflammatory Bowel Disease
  • Multiple and Secondary Primary Cancers
  • Colorectal Cancer Surgical Treatments
  • Gastroesophageal reflux and treatments
  • Eosinophilic Esophagitis
  • Colorectal Cancer Treatments and Studies
  • Helicobacter pylori-related gastroenterology studies
  • Pediatric Hepatobiliary Diseases and Treatments
  • Gallbladder and Bile Duct Disorders
  • Tumors and Oncological Cases
  • Antifungal resistance and susceptibility
  • Metastasis and carcinoma case studies
  • Abdominal Surgery and Complications
  • Nail Diseases and Treatments

Royal Brisbane and Women's Hospital
2015-2025

Liechtenstein Institute
2023

The University of Queensland
2021

Royal Brisbane and Women's Hospital Foundation
2006-2019

Princess Alexandra Hospital
2015

Prince Charles Hospital
2012

QIMR Berghofer Medical Research Institute
2006

McGill University
2006

Hospital Research Foundation
2006

State of The Art
2004

OBJECTIVE The objective of the study was to examine diagnosis and outcome in a series patients with small bowel tumors detected by capsule endoscopy (CE) three Australian centers. METHODS Review prospectively collected data from 416 CEs identified 27 26 patients. Clinical parameters, tumor histology, follow-up are reported. RESULTS Twenty-seven were (mean age 61 ± 13.7 yr). Indications for CE obscure gastrointestinal (GI) bleeding (21), suspected (3), abdominal pain (1), diarrhea (1). Prior...

10.1111/j.1572-0241.2006.00749.x article EN The American Journal of Gastroenterology 2006-10-01

Background Cold snare polypectomy (CSP) is the standard of care for resection small (< 10 mm) colonic polyps. Limited data exist its efficacy medium-sized (10–19 nonpedunculated polyps, especially conventional adenomas. This study evaluated effectiveness and safety CSP/cold endoscopic mucosal (C-EMR) Methods A prospective multicenter observational was conducted all morphologically suitable polyps 10–19 mm removed by CSP/C-EMR between May 2018 June 2021. Once complete, multiple biopsies...

10.1055/a-2029-9539 article EN Endoscopy 2023-02-07

Evidence-based nutritional and swallowing guidelines were developed to identify patients at high risk of developing malnutrition during chemoradiation for head neck cancer. These recommended a prophylactic gastrostomy actively implemented our institution in January 2007. This study assesses the effect this policy change on patient outcomes.This retrospective cohort was carried out years before (2005) after (2007) implementation these guidelines.In all, 165 treated with radical cancer 2005...

10.1002/hed.22992 article EN Head & Neck 2012-05-18

Increasing numbers of older patients with pancreatobiliary disease are undergoing endoscopic retrograde cholangiopancreatography (ERCP). Older may be at higher risk ERCP-related adverse events due to their age and comorbidities; however, data sparse. This study aimed evaluate long-term mortality, procedural outcomes safety ERCP in nonagenarians. We retrospectively evaluated consecutive aged ≥90 years who underwent a tertiary hospital over 12 years. The primary outcome was survival. Secondary...

10.1111/imj.16652 article EN Internal Medicine Journal 2025-03-01

This study aimed to characterize the mucosa-associated microbiota in ileal Crohn's disease [CD] patients and healthy controls terms of host genotype inflammation status.The microbiotas intestinal pinch biopsies from 15 CD with mild moderate 58 were analysed based on 16S ribosomal sequencing determine microbial profile differences between [1] IL23R, NOD2 ATG16L1 genotypes subjects, [2] control [3] inflamed non-inflamed mucosal tissue patients.The protective variant IL23R gene [rs11209026]...

10.1093/ecco-jcc/jjy188 article EN Journal of Crohn s and Colitis 2018-11-14

Abstract Introduction Gastrostomy insertion either via radiological (radiologically inserted gastrostomy, RIG) or endoscopic (percutaneous PEG) approaches are widely practiced throughout Australia. The purpose of this study was to compare outcomes tubes and cost evaluation by both methods. Methods A retrospective cohort conducted on all‐cause gastrostomy insertions at a quaternary Australian Hospital, Royal Brisbane Womens' Hospital (RBWH) between January 2012 August 2015. Current referral...

10.1111/1754-9485.12932 article EN Journal of Medical Imaging and Radiation Oncology 2019-08-11

Increased colonic butyrate from microbial fermentation of fibre may protect colorectal cancer (CRC). Dietary butyrylated high amylose maize starch (HAMSB) delivers to the large bowel. The objective this clinical trial (AusFAP) is evaluate potential chemoprotective effects HAMSB on polyposis in individuals with a genetic form colon cancer, Familial Adenomatous Polyposis (FAP). study multi-site, double blind, randomised, placebo-controlled crossover undertaken at major hospitals Australia....

10.1016/j.conctc.2023.101092 article EN cc-by-nc-nd Contemporary Clinical Trials Communications 2023-02-14

Background and Study Aims: The role of acetic acid spray during magnification chromocolonoscopy has not previously been evaluated. We aimed to compare the accuracy predicting polyp histology at colonoscopy, using indigo carmine, either alone or in combination. Patients Methods: A total 46 consecutive patients with polyps detected colonoscopy which measured 10 mm less were alternately divided into two groups. In group patients, 1.5 % was applied mucosa first, followed by carmine spray; B...

10.1055/s-2006-925001 article EN Endoscopy 2006-06-01

Demand for gastrointestinal endoscopy in Australia is increasing as a result of the expanding national bowel cancer screening program and growing, ageing population. More services are required to meet demand ensure patients seen within clinically recommended timeframes. A discrete event simulation model was developed project waiting list outcomes two large metropolitan health encompassing 8 public hospitals Australia. The applied routinely collected service data forecast impacts future...

10.1186/s12913-019-4438-x article EN cc-by BMC Health Services Research 2019-08-29

Repeated intentional foreign body ingestion (RIFBI) in patients with Emotionally Unstable Personality Disorder (EUPD) is a common clinical presentation to the emergency department. The relationship between repeated and co-existent personality disorder diagnosis complex, making it challenging manage. Our institution implemented novel interdisciplinary model of care for RIFBI as way improving health outcomes this cohort patients. observations following are presented herein. We encourage other...

10.1111/1742-6723.14451 article EN Emergency Medicine Australasia 2024-06-04

"Push" or "pull" techniques with the use of snares, forceps, baskets, and grasping devices are conventionally used to manage esophageal food bolus impaction (FBI). A novel cap-assisted technique has recently been advocated reduce time taken for (FB) removal. This study aimed compare effectiveness against conventional methods FB removal in a randomized controlled trial.Consecutive patients FBI requiring endoscopic removal, from 3 Australian tertiary hospitals between 2017 2019, were either...

10.14309/ajg.0000000000001484 article EN The American Journal of Gastroenterology 2021-09-20
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