- Inflammatory Bowel Disease
- Mycobacterium research and diagnosis
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Systemic Lupus Erythematosus Research
- Intraperitoneal and Appendiceal Malignancies
- Immunodeficiency and Autoimmune Disorders
- Endometriosis Research and Treatment
- Microscopic Colitis
- Gastric Cancer Management and Outcomes
- Tuberculosis Research and Epidemiology
- Food Quality and Safety Studies
- Viral Infections and Vectors
- Blood disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Cutaneous Melanoma Detection and Management
- Ocular Infections and Treatments
- Mosquito-borne diseases and control
- Clostridium difficile and Clostridium perfringens research
- Bacterial Identification and Susceptibility Testing
- Herpesvirus Infections and Treatments
- Venous Thromboembolism Diagnosis and Management
- Retinal and Optic Conditions
Mater Private Hospital
2017
QIMR Berghofer Medical Research Institute
2008-2016
Royal Brisbane and Women's Hospital
2002-2016
The University of Queensland
2016
University of Northern Colorado
2015
The Royal Children's Hospital Foundation
2008
Royal Brisbane and Women's Hospital Foundation
2008
State of The Art
2004
The first major Crohn's disease (CD) susceptibility gene, NOD2, implicates the innate intestinal immune system and other pattern recognition receptors in pathogenesis of this chronic, debilitating disorder. These include Toll-like receptors, specifically TLR4 TLR5. A variant gene (A299G) has demonstrated variable association with CD. We aimed to investigate relationship between A299G TLR5 N392ST, an Australian inflammatory bowel cohort, explore strength CD using global meta-analysis. Cases...
Background and Study Aims: The role of acetic acid spray during magnification chromocolonoscopy has not previously been evaluated. We aimed to compare the accuracy predicting polyp histology at colonoscopy, using indigo carmine, either alone or in combination. Patients Methods: A total 46 consecutive patients with polyps detected colonoscopy which measured 10 mm less were alternately divided into two groups. In group patients, 1.5 % was applied mucosa first, followed by carmine spray; B...
Background & Aims: Angiotensin II (AII) is a powerful splanchnic vasoconstrictor with pro-inflammatory and pro-fibrotic properties. converting enzyme (ACE) inhibitors AII Receptor Antagonists (ARBs) are therapeutic in animal models of colitis. The aim this case-control study to determine the expression angiotensinogen related genes human ileal Crohn’s disease.
 Methods: Using quantitative real-time polymerase chain reaction (RT-PCR), we measured mRNA levels (AGT), hypoxia inducible...
Background Immunosuppressed inflammatory bowel disease ( IBD ) patients have an increased risk of herpes zoster virus HZV infection. The existing live‐attenuated vaccine is contraindicated in some these and can only be used with caution others. Aims To describe characteristics suffering to enable implementation mitigation strategies for those at highest risk. Methods Gastroenterologists completed a proforma who experienced infection: phenotype, details infection, immunosuppression any change...
Modoc virus (MODV) is a flavivirus that was first isolated from deer mice ( Peromyscus maniculatus ) in County, California during 1958 surveillance study for novel viruses. Although many flaviviruses are arthropod-borne, MODV has no known intermediate. Subsequent to its initial isolation, detected found other regions of the United States, including northeastern Colorado. These findings suggested may be reservoir host MODV. We intramuscularly inoculated 18 with 10 5 TCID 50 strain M544...