- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Animal Virus Infections Studies
- RNA and protein synthesis mechanisms
- Hydrogels: synthesis, properties, applications
- Cytomegalovirus and herpesvirus research
- Bacteriophages and microbial interactions
- Laser Applications in Dentistry and Medicine
- Corneal Surgery and Treatments
- Antimicrobial agents and applications
Weifang Medical University
2020-2025
People's Hospital of Xinjiang Uygur Autonomous Region
2024
Shandong Center for Disease Control and Prevention
2022
National Institute for Viral Disease Control and Prevention
2020
Enterovirus A71 (EV-A71) is one of the main pathogens causing hand, foot, and mouth disease (HFMD) outbreaks in Asian children under 5 years age. In severe cases, it can cause neurological complications be life-threatening. this study, 200 newly sequenced EV-A71 whole-genome sequences were combined with 772 from GenBank for large-scale analysis to investigate global epidemiology, phylogeny, Bayesian phylodynamic characteristics. Based on phylogenetic 3Dpol region, six new evolutionary...
EV-A120 is a recently identified serotype of the enterovirus A species. Only one full-length genomic sequence currently available in GenBank, and very few studies have been conducted on globally. Thus, additional information research are needed to explore its genetic characteristics, phylogeny, relationship with enteroviral disease. In this study, we report phylogenetic characteristics strain (Q0082/XZ/CHN/2000) from Tibet, China. The amino acid similarity nucleotide prototype were 96.3%...
Abstract Enterovirus B83 (EV-B83) is a new member of the enterovirus B group. Currently, there are only two full-length genomic sequences EV-B83 in GenBank database and few VP1 region sequences. The aetiology epidemiology unclear. 24 stool specimens were collected from twelve AFP patients 298 healthy children support polio eradication activities Tibet 1999. Two polioviruses (isolated by L20B cell) one non-polio RD isolated nine 90 enteroviruses health children. Through molecular typing, we...
Novel posa-like viral genomes were first identified in swine fecal samples using metagenomics and designated as unclassified viruses the order Picornavirales. In present study, nine husavirus strains China. Their share 94.1–99.9% similarity, alignment of these 697 nucleotide polymorphism sites across their full-length genomes. These directly clustered with Husavirus 1 lineage, genomic arrangement showed similar characteristics. have undergone a complex evolutionary process, wide geographic...
EV-B93 is a novel serotype within the Enterovirus B species and uncommon worldwide. Currently, only one full-length genomic sequence (the prototype strain) has been deposited in GenBank database. In this study, three were identified, including from an acute flaccid paralysis (AFP) patient (named 99052/XZ/CHN/1999, hereafter XZ99052) two healthy children 99096/XZ/CHN/1999 99167/XZ/CHN/1999, XZ99096 XZ99167, respectively) Tibet 1999 during polio eradication program. The identity between...