A5085890188- Probiotics and Fermented Foods
- Gut microbiota and health
- Dermatology and Skin Diseases
- Mosquito-borne diseases and control
- Viral gastroenteritis research and epidemiology
- Aquaculture disease management and microbiota
- Phytochemicals and Antioxidant Activities
- Protein Hydrolysis and Bioactive Peptides
- Biochemical Analysis and Sensing Techniques
- Antifungal resistance and susceptibility
- Aquaculture Nutrition and Growth
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 and COVID-19 Research
- Fish Biology and Ecology Studies
- Computational Drug Discovery Methods
- Microbial Metabolites in Food Biotechnology
- Bacterial biofilms and quorum sensing
- Genomics and Phylogenetic Studies
- Nanoparticles: synthesis and applications
- Antimicrobial Peptides and Activities
- Antimicrobial Resistance in Staphylococcus
- interferon and immune responses
- Viral Infections and Vectors
- Enzyme Production and Characterization
- Psoriasis: Treatment and Pathogenesis
King Abdulaziz University
2019-2025
Yeungnam University
2012-2023
King Abdul Aziz University Hospital
2020
Daegu University
2017
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing severe invasive infections associated with high mortality rates in hospitalized individuals. Distinct from other species, C. auris can persist longer periods on different surfaces and resistant to all of the major classes antifungal drugs. Therefore, there urgent need new antimycotic drugs improved efficacy reduced toxicity. The development antifungals based antimicrobial peptides various sources considered...
The aims of the study were to isolate anti-H9N2 bacteria from Korean Kimchi isolates and evaluate its performance in cell line, egg specific pathogen-free (SPF) chickens. Using Madin-Darby canine kidney (MDCK) 220 bacterial screened YML003 was selected having pronounced antiviral activity against H9N2 virus. This identified as Leuconostoc mesenteroides by 16S rRNA gene sequencing. Anti-H9N2 strain also evaluated hemagglutination assay. assessed for survival gastric juice 5% bile acid...
Korean kimchi is known for its myriad of lactic acid bacteria (LAB) with diverse bioactive compounds. This study was undertaken to isolate an efficient antifungal LAB strain among the isolated LABs. One thousand and four hundred LABs from different samples were initially screened against Aspergillus niger. The exhibiting highest activity identified as Lactobacillus plantarum YML007 by 16S rRNA sequencing biochemical assays using API 50 CHL kit. Lact. further oryzae, flavus, Fusarium...
This study was designed to evaluate the protective effect of ethanol extract (EEL1) isolated from a potent probiotic strain Lactobacillus sakei proBio-65 on imiquimod (IMQ)-induced psoriasis-like skin inflammation in mouse model. Histopathological and histomorphometrical changes ear dorsal tissues were observed under hematoxylin eosin stain for general histopathological architectures or Masson's trichrome collagen fibers. The expression profile psoriasis-associated specific genes determined...
The aim of the present study was to examine antioxidative activity (+)-lariciresinol (LRSL), an optically active lignan isolated from Rubia philippinensis in several vitro assays. LRSL also subjected evaluate its inhibitory effect against generation reactive oxygen species (ROS) murine macrophage (RAW 264.7) cells. results showed that possessed very strong radical scavenging and reducing power, as well inhibited ROS a dose-dependent manner without showing any cytotoxicity. transcriptional...
Abstract In this study, the authors investigated anti-melanogenic effects of 3,8-dihydroxyquinoline (jineol) isolated from Scolopendra subspinipes mutilans , mechanisms responsible for its inhibition melanogenesis in melan-a cells, and antioxidant efficacy. Mushroom tyrosinase activities melanin contents were determined protein mRNA levels MITF, tyrosinase, TYRP-1, TYRP-2 assessed. Jineol exhibited significant, concentration-dependent as by DPPH, ABTS, CUPRAC, FRAP assays. significantly...
In response to the ongoing COVID-19 pandemic, global effort develop high efficacy countermeasures control infection are being conducted at full swing. While of vaccines and coronavirus drugs tested, microbiome approach represents an alternative pathophysiology-based prevent severity infection. current study, we evaluated action a novel probiotic Lactobacillus plantarum Probio-88 against SARS-COV-2 replication immune regulation using in vitro silico study. The results showed that extract...
The inhibition of acetylcholinesterase (AChE) by cholinergic agents has been promoted as a potent strategy for treating and managing cognitive decline disorders. A wide range natural products long used potential sources or formulations inhibitors. Therefore, this study aimed to evaluate different Rosmarinus officinalis L. (R. officinalis) extracts their AChE inhibitory activity using galanthamine standard inhibitor. In study, the ethyl-acetate extract (at concentration 250 µg/mL) exhibited...
Abstract: This study was aimed to partially purify the exopolysaccharide (EPS) from culture of Lactobacillus plantarum YML009 using ethanol precipitation method with a yield 260 mg/L. Analytical evaluationby Bradford and Phenolsulphuric methods revealed presence 2.2% 68.1% total protein sugar contents in purified EPS, respectively. Further, confirm biological potential, EPS evaluated for its antioxidant activity various scavenging models including DPPH nitrite radicals as well reducing power...
This study was undertaken to characterize a lactic acid bacterium 4I1, isolated from the freshwater fish, Zacco koreanus. Morphological, biochemical, and molecular characterization of 4I1 revealed it be Pediococcus pentosaceus 4I1. The cell free supernatant (CFS) P. exhibited significant (p < 0.05) antibacterial effects (inhibition zone diameters: 16.5-20.4 mm) against tested foodborne pathogenic bacteria with MIC MBC values 250-500 500-1,000 μg/mL, respectively. Further, action CFS two...
Amaranth (Amaranthus hypochondriacus Linn.) is an important pseudocereal crop having nutrients along with the indispensable amino-acids. The present study was aimed to effect of plant growth promoting bacilli on proximate constituents amaranth grains, including three essential amino acids (methionine, lysine and, tryptophan). combination Bacillus pumilus and subtilis showed a significant increase in different constituents, crude protein (22.13%), dry matter (32.25%), fat (30.77%),...
Cyclin-dependent kinase 2 (CDK2) is an essential protein involved in the cell cycle regulation. The abnormal activity of CDK2 associated with cancer progression and metastasis. Here, we have performed structure-based virtual screening PubChem database to identify potent inhibitors. First, retrieved all compounds from having at least 90% structural similarity known selected were subjected molecular docking studies investigate their pattern interaction estimate binding affinities CDK2....