- Probiotics and Fermented Foods
- Essential Oils and Antimicrobial Activity
- Insect behavior and control techniques
- Insect symbiosis and bacterial influences
- Ethnobotanical and Medicinal Plants Studies
- Insect Utilization and Effects
- Gut microbiota and health
- Biochemical Analysis and Sensing Techniques
- Viral gastroenteritis research and epidemiology
- Botanical Research and Chemistry
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Microbial Metabolites in Food Biotechnology
- Gastrointestinal motility and disorders
- Natural Antidiabetic Agents Studies
- Aquaculture disease management and microbiota
- Food Quality and Safety Studies
- Botany, Ecology, and Taxonomy Studies
- Entomopathogenic Microorganisms in Pest Control
- Natural Compound Pharmacology Studies
- biodegradable polymer synthesis and properties
- Respiratory viral infections research
- Computational Drug Discovery Methods
- Genomics, phytochemicals, and oxidative stress
Macquarie University
2016-2024
Centenary Institute
2022-2024
University of Technology Sydney
2022-2024
Centre for Inflammation Research
2024
Botanical Survey of India
1977-2024
Yeungnam University
2015-2022
Adamas University
2022
New South Wales Department of Primary Industries
2016-2022
Atish Dipankar University of Science and Technology
2014
Objective Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms pathogenesis remain poorly understood, limiting the development effective therapies. gastrointestinal microbiome has been implicated in chronic lung diseases via gut-lung axis, but its role unclear. Design Using an vivo mouse model smoke (CS)-induced COPD faecal microbial transfer (FMT), we characterised microbiota using metagenomics,...
The aim of the present study was to examine antioxidative activity (+)-lariciresinol (LRSL), an optically active lignan isolated from Rubia philippinensis in several vitro assays. LRSL also subjected evaluate its inhibitory effect against generation reactive oxygen species (ROS) murine macrophage (RAW 264.7) cells. results showed that possessed very strong radical scavenging and reducing power, as well inhibited ROS a dose-dependent manner without showing any cytotoxicity. transcriptional...
Abstract In this study, the authors investigated anti-melanogenic effects of 3,8-dihydroxyquinoline (jineol) isolated from Scolopendra subspinipes mutilans , mechanisms responsible for its inhibition melanogenesis in melan-a cells, and antioxidant efficacy. Mushroom tyrosinase activities melanin contents were determined protein mRNA levels MITF, tyrosinase, TYRP-1, TYRP-2 assessed. Jineol exhibited significant, concentration-dependent as by DPPH, ABTS, CUPRAC, FRAP assays. significantly...
Abstract We examined the anti-inflammatory effects of (+)-syringaresinol (SGRS), a lignan isolated from Rubia philippinensis , in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells using enzyme-based immuno assay, Western blotting, and RT-PCR analyses. Additionally, vivo SGRS acute inflammatory state were by carrageenan-induced hind paw edema assay experimental mice. As result, treatment with (25, 50, 100 μM) inhibited protein expression lipopolysaccharide-stimulated inducible nitric oxide...
<p>Chromatographic techniques have significant role in natural products chemistry as well contribute dramatically the discovery of novel and innovative compounds pharmaceutical biomedical importance. This study focused on step-by-step visual demonstration fractionation isolation biologically active plant secondary metabolites using column-chromatographic techniques. Isolation bioactive involves: a) Preparation sample; b) Packing column; c) Pouring sample into d) Elution fractions; e)...
<p class="Abstract">Lactic acid bacteria exhibit the most effective potential to divert significant amount of fermentable sugars towards biosynthesis functional exopolysaccharide. Exopolysaccharides from lactic are receiving a renewed interest due claims human health benefits. This review provides an update on multiple uses and production exopolysaccharides with major emphasis their chemical properties, characterization, some other molecular strategies adopted for genetics biological...
<p>Lactic acid bacteria are classified ‘Generally Recognized As Safe’ (GRAS) with most effective potential to divert significant amount of fermentable sugars towards the biosynthesis functional exopolysaccharide. Exopolysaccharides from lactic receiving a renewed interest due claims human health benefits, such as modulation immune response system and more importantly in food pharma industries texturizer, viscosifer, emulsifier syneresis-lowering agent. Its purification methodology...
This study characterized a lactic acid bacterium Leuconostoc mesenteroides HJ69 at biochemical and molecular level, isolate from traditional Korean fermented food Kimchi. Cell free supernatant (CFS) of L. exhibited significant (P < 0.05) antibacterial effect as diameters inhibition zones (14.34 ± 0.31 – 18.21 0.23 mm) against the tested foodborne pathogenic bacteria with minimum inhibitory concentration bactericidal values found in range 250–2,000 500–2,000 μg/mL, respectively. Further, CFS...
Bactroceratryoni (Froggatt) (Queensland fruit fly, or "Qfly") is a highly polyphagous tephritid fly and serious economic pest in Australia. Qfly biology intimately linked to the bacteria fungi of its microbiome. While there are numerous studies microbiome larvae adults, transition through pupal stage remains unknown. To address this knowledge gap, we used high-throughput Next-Generation Sequencing (NGS) examine microbial communities at each developmental life cycle, targeting bacterial 16S...
Abstract Dengue virus, particularly serotype 2 (DENV-2), poses a significant global health threat, and understanding the molecular basis of its interactions with host cell proteins is imperative for developing targeted therapeutic strategies. This study elucidated between proline-enriched motifs Src homology 3 (SH3) domain. The SH3 domain pivotal in mediating protein–protein interactions, by recognizing binding to proline-rich regions partner proteins. Through computational pipeline, we...
This study underpins the therapeutic potential of SEL001, a bioactive product isolated from
Abstract Insects typically host substantial microbial communities (the ‘microbiome’) that can serve as a vital source of nutrients and also acts modulator immune function. While recent studies have shown diet is an important influence on the gut microbiome, very little known about dynamics underpinning acquisition from natural food sources. Here, we addressed this gap by comparing microbiome larvae polyphagous fruit fly Bactrocera tryoni (‘Queensland fly’) were collected five different types...
There are still a large variety of microorganisms among aquatic animals which have not been explored for their pharmacological potential. Hence, present study was aimed to isolate and characterize potent lactic acid bacterium from fresh water fish sample Zacco koreanus, confirm its Isolation bacteria (LAB) samples done using serial dilution method. Biochemical identification molecular characterization selected LAB 1I1, based on antimicrobial efficacy, accomplished API kit 16S rRNA gene...
The transition from nature to laboratory or mass rearing can impose significant physiological and evolutionary impact on insects. Queensland fruit fly (also known as 'Qfly'), Bactrocera tryoni (Froggatt) (Diptera: Tephritidae), is a serious economic pest that presents major challenges for horticulture industries in Australia. sterile insect technique (SIT) being developed manage outbreaks regions remain free of Qfly suppress populations where this species endemic. biology intimately...
Larval diets used for artificial rearing can have a significant effect on insect biology. The Queensland fruit fly (aka 'Qfly'), Bactrocera tryoni (Froggatt) (Diptera: Tephritidae), is one of the greatest challenges growers in Australia. sterile technique (SIT) being developed to manage outbreaks regions that remain free Qfly and reduce populations where this species endemic. Factory scale essential SIT; however, larval are known affect microbiome Qfly, which may then performance. In study,...
The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation tumor cells into mice, extracts were administered at 25, 50 100 mg/kg body weight for nine consecutive days. effects then assessed according volume, packed cell count, viable non-viable median survival...
Abstract Bactrocera tryoni (Froggatt), the Queensland fruit fly (Qfly), is a highly polyphagous tephritid that widespread in Eastern Australia. Qfly physiology closely linked with its fungal associates, particular relationship between nutrition and yeast or yeast-like fungi. Despite animal-associated fungi typically occurring multi-species communities, studies have predominately involved culture characterisation of single isolates. Further, only two investigated communities associated Qfly,...
The Journal of the National Science Foundation Sri Lanka publishes results research in all aspects and Technology. journal also has a website at http://www.nsf.gov.lk/. 2021 Impact Factor: 0.682The JNSF provides immediate open access to its content on principle that making freely available public supports greater global exchange knowledge.Cover :Leatherback (a), green (b - adult & f hatchling), hawksbill (c) olive ridley (d) turtles who nest Lankan beaches, turtle crawl marks (e) by-catch...
Lactic acid bacteria are one of the potential natural remedies used worldwide, commonly known as probiotics. Here, aim this research investigation was to isolate a probiotic Lactobacilli strain, YLM015, from popular Korean fermented vegetable “Kimchi” and evaluate its anti-viral against influenza virus A (IFVA) H1N1 using MDCK cell line in vitro, embryonated eggs ovo. The YML015 strain selected among 1200 isolates for further studies based on potent efficacy. identified characterized...
<p>Serum pathogen-free (SPF) embryonated egg for culturing virus has three main steps: a) candling of egg, b) inoculation and c) harvesting inoculated egg. Furthermore, hemagglutination assay consists only one step. The method is easy to perform. However, this experiment must be performed in a class 2 biosafety cabinet.</p><p><strong>INTRODUCTION</strong></p><p>More than 200,000 hospitalizations around 36,000 deaths are associated with influenza...