A5049702565- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Eating Disorders and Behaviors
- Mental Health Research Topics
- Parkinson's Disease Mechanisms and Treatments
- Obesity, Physical Activity, Diet
- Obsessive-Compulsive Spectrum Disorders
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Children's Physical and Motor Development
- Child Nutrition and Feeding Issues
- Neurological disorders and treatments
- Attention Deficit Hyperactivity Disorder
- Behavioral Health and Interventions
- Autism Spectrum Disorder Research
- Libraries and Information Services
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- German Literature and Culture Studies
- Early Childhood Education and Development
- Infant Development and Preterm Care
- European history and politics
- Schizophrenia research and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Mindfulness and Compassion Interventions
University of Basel
2016-2025
Justus-Liebig-Universität Gießen
2025
University of Fribourg
2018-2024
Northeastern University
2024
Czech Academy of Sciences, Institute of Psychology
2023
Landwirtschaftskammer Niedersachsen
2023
University Hospital of Basel
2009-2022
Technische Universität Berlin
2021
University Hospital Regensburg
2021
TU Bergakademie Freiberg
2021
Pulmonary hypertension during exercise is common in severe chronic obstructive pulmonary disease (COPD). It was hypothesised that the use of endothelin-receptor antagonist bosentan can improve cardiopulmonary haemodynamics exercise, thus increasing tolerance patients with COPD. In present double-blind, placebo-controlled study, 30 or very COPD were randomly assigned a 2:1 ratio to receive either placebo for 12 weeks. The primary end-point change 6-min walking distance. Secondary end-points...
Environmentally induced epigenetic alterations are related to mental health. We investigated quantitative DNA methylation status before and after an acute psychosocial stressor in two stress-related genes: oxytocin receptor (OXTR) brain-derived neurotrophic factor (BDNF ). The cross sectional study took place at the Division of Theoretical Clinical Psychobiology, University Trier, Germany was conducted from February August 2009. included 83 participants aged 61–67 years. Thereof, 76...
Background/Objective: Prolonged stress can overwhelm coping resources, leading people to seek mental health care. Acceptance and commitment therapy (ACT) is an intervention that enhances well-being reduces distress, assumedly by means of increasing psychological flexibility (PF). We examined the association between a total increase in PF during decreases increases after intervention. Method: The was randomized controlled trial ACT-based self-help Participants were 91 individuals reporting...
Summary 1 Utilization of carbon sources by culturable soil bacteria can be assessed with BIOLOG microtiter plates (contain 31 C sources). We used this technique to investigate bacterial community structure at various levels plant diversity. Plant diversity were replicated and we investigated the influence three functional groups, grasses, legumes non‐leguminous herbs, as well individual species. 2 Catabolic activity catabolic estimate their density (abundance) diversity, respectively. Both...
In adults, reporting low and high maternal care in childhood, we compared DNA methylation two stress-associated genes (two target sequences the oxytocin receptor gene, OXTR; one brain-derived neurotrophic factor BDNF) peripheral whole blood, a cross-sectional study (University of Basel, Switzerland) during 2007–2008. We recruited 89 participants scoring < 27 (n = 47, 36 women) or > 33 42, 35 on subscale Parental Bonding Instrument (PBI) at previous assessment larger group (N 709, range PBI...
Abstract Research on open-label placebos questions whether deception is a necessary characteristic of placebo effects. Yet, comparisons between and deceptive (DPs) are lacking. We therefore assessed effects DPs in comparison with no treatment (NT) standardized experimental heat pain paradigm randomized controlled trial healthy participants. Participants (N = 160) were randomly assigned to NT, without rationale (OPR-), (OPR + ), DP. conducted baseline posttreatment measurements threshold...
Identifying healthy lifestyle behaviours that promote psychological wellbeing is crucial to preventing mental disorders. The aim of the current study was evaluate individual and combined associations between different aspects everyday life health within a representative community sample in Germany. conducted 2012/2013 included 7,937 participants German population. Lifestyle factors were assessed via self-report frequency physical activity, alcohol consumption, smoking, body mass index as...
Identifying ways to promote physical activity and decrease sedentary time during childhood is a key public health issue. Research on the putative influences preschool children's (PA) behavior (SB) limited has yielded inconsistent results. Our aim was identify correlates of PA SB in children. Cross-sectional data were drawn from Swiss Preschoolers' Health Study (SPLASHY), population-based cohort study. Of 476 two six year old children, 394 (54% boys) had valid assessed by accelerometry....
Amphibians are in decline many parts of the world. Long tme-series amphibian populations necessary to distinguish declines from often strong fluctuations observed natural populations. Time-series may also help understand causes these declines. We analysed 23-28-year long time-series frog Rana temporaria. Only one three studied showed a negative trend which was probably caused by introduction fish. Two appeared be density regulated. Rainfall had no obvious effect on population fluctuations....
Abstract Objectives: The aim of this study was to determine the efficacy cognitive‐behavioral therapy (CBT) and behavioral weight loss treatment (BWLT) for overweight patients with binge eating disorder (BED). Method: Eighty obese meeting criteria BED according DSM‐IV‐TR were randomly assigned either CBT or BWLT consisting 16 weekly treatments 6 monthly follow‐up sessions. Binge eating, general psychopathology, body mass index (BMI) assessed before, during, after treatment, at 12‐month...
Combined sedation with a benzodiazepine and an opiate has been proposed as standard for bronchoscopy. Propofol is sedative–hypnotic rapid onset of action fast recovery time, but carries the potential risk respiratory failure. Consecutive patients (n = 200) were randomly allocated to receive either combination midazolam hydrocodone or intravenous propofol. The primary end-points mean lowest arterial oxygen saturation during bronchoscopy readiness-for-discharge score 1 h after procedure. did...
To study in a large-scale cohort with prospective data the associations of psychosocial adversities during pregnancy length gestation and offspring size at birth.We defined priori two types adversity pregnancy: life stress (perceived burdens major areas life) emotional symptoms (e.g. anxiety). Measures birth, including body weight, length, abdominal head circumference, were obtained from national medical birth registry. We included analyses gestational age controlled for gestation; latter...
Background: Nonresponsiveness to therapy is generally acknowledged, but only a few studies have tested switching psychotherapy. This study one of the first examine malleability treatment-resistant patients using acceptance and commitment (ACT). Methods: was randomized controlled trial that included 43 diagnosed with primary panic disorder and/or agoraphobia (PD/A) prior unsuccessful state-of-the-art treatment (mean number previous sessions = 42.2). Patients were treated an ACT manual...
Objectives: To find out which Quantitative EEG (QEEG) parameters could best distinguish patients with Parkinson's disease (PD) and without Mild Cognitive Impairment from healthy individuals to an optimal method for feature selection. Background: Certain QEEG have been seen be associated dementia in Alzheimer's disease. Studies also shown some dependent on the stage of We wanted investigate differences high-resolution measures between groups PD individuals, come up a small subset features...
The aim of this study was to investigate whether maternal adversities and cortisol levels during pregnancy predict cord blood DNA methylation the oxytocin receptor (OXTR). We collected 39 babies born mothers participating in a cross-sectional (N = 100) conducted Basel, Switzerland (2007–10). Mothers completed Inventory Life Events (second trimester: T2), Edinburgh Postnatal Depression Scale (EPDS, third T3), Trier Chronic Stress (TICS-K, 1–3 weeks postpartum) provided saliva samples (T2, T3)...
The role of specific phobia as a potentially important psychopathological precursor condition to more severe mental disorders is understudied. We examined the prospective-longitudinal association early childhood/adolescent with subsequent and proportion outcome disease incidence attributable simultaneously for broad range disorders.N = 2210 14- 24-year-old community subjects were followed up 10 years. DSM-IV-specific exposure DSM-IV outcomes assessed DSM-IV/M-CIDI. Logistic regressions,...
Background Normal motor development and adequate levels of engagement in physical activity during the early years life form foundation long-term psychological physiological health. This is one very few studies that investigate stability relationships competence preschool children. Methods Baseline 12-month follow-up data 550 children aged 2 to 6 from Swiss Preschoolers’ Health Study were used for this work. Physical data, expressed counts per minute total minutes day time spent...