Danielle Murici Brasiliense

ORCID: 0000-0003-2772-639X
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Reproductive tract infections research
  • Bacterial biofilms and quorum sensing
  • Adolescent Sexual and Reproductive Health
  • Vibrio bacteria research studies
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotic Use and Resistance
  • Infections and bacterial resistance
  • Cervical Cancer and HPV Research
  • Syphilis Diagnosis and Treatment
  • Salmonella and Campylobacter epidemiology
  • Urinary Tract Infections Management
  • Bacterial Identification and Susceptibility Testing
  • Enterobacteriaceae and Cronobacter Research
  • Microbial Metabolism and Applications
  • Psychology and Mental Health
  • Gut microbiota and health
  • Youth, Drugs, and Violence
  • Cultural, Media, and Literary Studies
  • Urban and sociocultural dynamics
  • Escherichia coli research studies
  • Bacteriophages and microbial interactions
  • Social Media and Politics
  • Impact of Technology on Adolescents
  • Cystic Fibrosis Research Advances

Instituto Evandro Chagas
2015-2025

Ministério da Saúde
2022-2025

Universidade do Estado do Pará
2023-2025

Amazon (United States)
2025

Universidade Federal do Ceará
2022

Universidade Federal Fluminense
2013-2020

Clinical emergent bacterial pathogens are a great threat to the global health system, chiefly Gram-negative carbapenem-resistant Enterobacterales and Klebsiella pneumoniae species complex. Here, we present molecular phenotypic characterization of quasipneumoniae subs. similipneumoniae IEC57090 strain, belonging ST138 showing multidrug resistance phenotype. The blaNDM-7 in one two plasmids carried by isolate, antibiotic genes fosA, oqxAB, acrR, gene mutations on porins ompK36 ompK37, both...

10.3390/microorganisms13020314 article EN cc-by Microorganisms 2025-02-01

Pseudomonas aeruginosa is a major pathogen in cystic fibrosis (CF), where chronic and intermittent infections significantly affect patient outcomes. This study aimed to investigate the molecular epidemiology of P. CF patients from Brazilian Amazon, focusing on genotypic diversity, resistance profiles, virulence factors. A cross-sectional included 72 isolates 44 treated at regional reference center between 2018 2019. Antimicrobial susceptibility patterns were determined using VITEK-2 system...

10.1186/s12866-025-03920-w article EN cc-by-nc-nd BMC Microbiology 2025-04-09

Pseudomonas aeruginosa is a high-priority bacterial agent that causes healthcare-acquired infections (HAIs), which often leads to serious and poor prognosis in vulnerable patients. Its increasing resistance antimicrobials, associated with SPM production, case of public health concern. Therefore, this study aims determine the antimicrobial resistance, virulence, genotyping features P. strains producing SPM-1 Northern region Brazil. To presence virulence genes, PCR technique was used. For...

10.3390/microorganisms11082069 article EN cc-by Microorganisms 2023-08-11

Abstract Objectives To characterize a novel acquired MBL, BIM-1, in Pseudomonas #2 (subgroup P. guariconensis) strain isolated from the Aurá river located Brazilian Amazon hydrographic basin. Methods WGS using an Illumina® MiSeq System was used to genome of sp. IEC33019 strain. Southern blotting/hybridization assays were performed confirm location MBL-encoding gene, blaBIM-1 (Belém Imipenemase). Antimicrobial susceptibility testing, cloning, and biochemical phenotypic characterization...

10.1093/jac/dkad077 article EN cc-by-nc Journal of Antimicrobial Chemotherapy 2023-02-28

Abstract Aims The present study aimed to use a conventional and metagenomic approach investigate the microbiological diversity of water bodies in network drainage channels rivers located central area city Belém, northern Brazil, which is considered one largest cities Brazilian Amazon. Methods results In eight analyzed points, both bacterial viral indicators environmental contamination—physical–chemical metals—were assessed. resistance genes, drug mechanisms, viability environment were also A...

10.1093/jambio/lxae101 article EN Journal of Applied Microbiology 2024-04-16

Introduction: Genital Chlamydia trachomatis infection is one of the most prevalent sexually transmitted diseases in women, and undetected cases disease are highly associated with long-term complications. Despite high prevalence infections Brazil, very little known about distribution C. genovars. In this study, we determined genotypes women treated at a public hospital Brazilian city Belém, capital state Pará. Methodology: A total 154 were tested for chlamydial by PCR using specific primers...

10.3855/jidc.6474 article EN cc-by The Journal of Infection in Developing Countries 2016-02-28

Background Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection (STI) in world. Approximately 80% of infected women are asymptomatic, although this can lead to serious complications female reproductive tract. Few data on available rural Amazonian communities. Objectives To evaluate prevalence sexual C. from Marajó Archipelago communities Amazon region Brazil and identify associated factors genotypes. Methods We utilized amplification ompA gene by nested PCR....

10.1371/journal.pone.0207853 article EN cc-by PLoS ONE 2018-11-29

Serratia marcescens is a Gram-negative bacterium presenting intrinsic resistance to polymyxins that has emerged as an important human pathogen. Although previous studies reported the occurrence of multidrug-resistance (MDR) S. isolates in nosocomial settings, herein, we described this extensively drug-resistant (XDR) species recovered from stool samples food-producing animals Brazilian Amazon region. Three carbapenem-resistant strains were poultry and cattle. Genetic similarity analysis...

10.1016/j.onehlt.2023.100591 article EN cc-by One Health 2023-06-21

OBJETIVOS: Descrever a prevalência e os fatores associados à infecção endocervical por Chlamydia trachomatis em estudantes de uma universidade da capital três seus campi do interior estado Pará, Amazônia, Brasil.

10.5123/s2176-62232017000300004 article PT cc-by-nc Revista Pan-Amazônica de Saúde 2017-09-01

The multidrug resistance (MDR) phenotype is frequently observed in Acinetobacter baumannii, the most clinically relevant pathogenic species of its genus; recently, other belonging to A. calcoaceticus-A. baumannii complex have emerged as important MDR nosocomial pathogens.The present study aimed verify occurrence metallo-β-lactamase genes among distinct a hospital located Brazilian Amazon Region.Antimicrobial susceptibility profiles were determined by broth microdilution. genetic...

10.1590/0074-02760190020 article EN cc-by Memórias do Instituto Oswaldo Cruz 2019-01-01

Abstract The One Health concept is a global strategy to study the relationship between human and animal health transfer of pathogenic non-pathogenic species these systems. However, best our knowledge, no data based on genome-centric metagenomics are available in public repositories. Here, we present dataset pilot-study 2,915 metagenome-assembled genomes (MAGs) 107 samples from (N = 34), cattle 28), swine 15) poultry 30) gut microbiomes. Samples were collected five Brazilian geographical...

10.1038/s41597-022-01465-5 article EN cc-by Scientific Data 2022-06-25

The epidemiology of antimicrobial resistance (AMR) is complex, with multiple interfaces (human-animal-environment). In this context, One Health surveillance essential for understanding the distribution microorganisms and genes (ARGs). This report describes a multicentric study undertaken to evaluate bacterial communities resistomes food-producing animals (cattle, poultry, swine) healthy humans sampled simultaneously from five Brazilian regions. Metagenomic analysis showed that total 21,029...

10.1128/spectrum.00565-22 article EN cc-by Microbiology Spectrum 2022-08-22

Background Approximately 80% of infected women by Chlamydia trachomatis are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on and genotypes available Amazonian communities. Objectives To describe prevalence associated factors identify sexual C . university students different urban centers (capital interiors) Brazilian state Pará, eastern Amazon region. Methods A cross-sectional study was performed among young attending...

10.1371/journal.pone.0287119 article EN cc-by PLoS ONE 2024-01-02

This study aimed to characterize a Klebsiella pneumoniae strain (KP411) recovered from the stool samples of poultry (Gallus gallus) in Brazilian Amazon Region. The whole-genome sequencing KP411 revealed presence an important arsenal antimicrobial resistance genes β-lactams (blaCTX-M-14, blaTEM-1B, blaKPC-2, blaSVH-11), aminoglycosides [aph(3″)- Ib, aph(6)-Id, aph(3′)-Ia], sulfonamides (sul1, sul2), quinolones (oqxAB), fosfomycin (fosAKP), and macrolides [mph(A)]. Furthermore, our analyses...

10.3390/antibiotics11121835 article EN cc-by Antibiotics 2022-12-17

The horizontal transfer of antibiotic resistance genes in Gram-negative bacteria, mainly through plasmids, is one the greatest concerns for health systems worldwide and has been a growing threat hospitals related to healthcare-associated infections by multidrug-resistant bacteria. Here we present p henotypic genomic characterization KPC-2 MCR-1.27-producing Klebsiella pneumoniae strain isolated from paediatric patient at an oncologic hospital Belém, Pará State, Brazilian Amazon...

10.1016/j.jgar.2023.04.009 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2023-04-23

Surgical site infection (SSI) following caesarean section is associated with increased morbidity, mortality, and significant health care costs. This study evaluated the epidemiological, clinical, microbiological features of Acinetobacter spp. in women SSIs who have undergone at a referral hospital Brazilian Amazon region. included 69 post-caesarean SSI by admitted to between January 2012 May 2015. The isolates were subjected molecular species identification, antimicrobial susceptibility...

10.3390/microorganisms9040743 article EN cc-by Microorganisms 2021-04-02

Carbapenem-resistant Klebsiella pneumoniae is a common cause of healthcare-related infections, and it widespread in hospitals diverse environments with potentially serious public health implications. Herein, we have reported the isolation characterization an environmental Brazilian carbapenemase (BKC-1)-producing K. strain (IEC1205) isolated 2018 from river Amazon region, Brazil. Antimicrobial susceptibility this was evaluated by broth microdilution demonstrated resistance to several...

10.1016/j.scitotenv.2022.157917 article EN cc-by-nc The Science of The Total Environment 2022-08-08

Klebsiella pneumoniae appears as one of the most prevalent pathogens among cancer patients. The present study investigates clinical, epidemiological and microbiological aspects related to infections caused by K. in patients treated at an oncology referral center state Pará, Amazon region, Brazil. Between July 2017 2019, epidemiological, observational, cross-sectional study, with a descriptive analytical approach was conducted, including confirmed diagnosis who acquired infection 72 h after...

10.3390/idr12030021 article EN cc-by Infectious Disease Reports 2020-12-03
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