A5007444333- Breast Cancer Treatment Studies
- Cancer survivorship and care
- Advanced Breast Cancer Therapies
- Medication Adherence and Compliance
- Economic and Financial Impacts of Cancer
- BRCA gene mutations in cancer
- Cancer Treatment and Pharmacology
- Family Support in Illness
- Global Cancer Incidence and Screening
- Health Systems, Economic Evaluations, Quality of Life
- Estrogen and related hormone effects
- Palliative Care and End-of-Life Issues
- Pharmaceutical Practices and Patient Outcomes
- Patient-Provider Communication in Healthcare
- HER2/EGFR in Cancer Research
- DNA Repair Mechanisms
- Biomedical Ethics and Regulation
- Chemotherapy-related skin toxicity
- Advanced MRI Techniques and Applications
- Cancer-related cognitive impairment studies
- PARP inhibition in cancer therapy
- Health Literacy and Information Accessibility
- Childhood Cancer Survivors' Quality of Life
- Urban Green Space and Health
- Pharmaceutical studies and practices
UNM Comprehensive Cancer Center
2009-2024
University of New Mexico
2012-2024
New Mexico Cancer Center
2012-2024
University of New Mexico Hospital
2020-2022
Daiichi Sankyo (Germany)
2020
Daiichi-Sankyo (South Korea)
2020
Amgen (Canada)
2020
Spectrum Pharmaceuticals (United States)
2020
Novartis (Switzerland)
2020
Samsung (India)
2020
Purpose To determine the pathologic complete response (pCR) rate in estrogen receptor (ER) –positive primary breast cancer triaged to chemotherapy when protein encoded by MKI67 gene (Ki67) level was > 10% after 2 4 weeks of neoadjuvant aromatase inhibitor (AI) therapy. A second objective examine risk relapse using Ki67-based Preoperative Endocrine Prognostic Index (PEPI). Methods The American College Surgeons Oncology Group (ACOSOG) Z1031A trial enrolled postmenopausal women with stage II...
ASCO Rapid Recommendation Updates highlight revisions to select guideline recommendations as a response the emergence of new and practice-changing data. The rapid updates are supported by an evidence review follow development processes outlined in Guideline Methodology Manual. goal these articles is disseminate updated recommendations, timely manner, better inform health practitioners public on best available cancer care options. Guidelines not intended substitute for independent...
The aim of this work is to update key recommendations the ASCO guideline adaptation Cancer Care Ontario on selection optimal adjuvant chemotherapy regimens for early breast cancer and targeted therapy cancer.An Expert Panel conducted a systematic literature review guided by signals approach identify new, potentially practice-changing data that might translate into revised recommendations.The reviewed abstracts from identified one article inclusion reported results phase III, open-label...
Nonadherence to aromatase inhibitors (AIs) for breast cancer is common and increases the risk of recurrence. Text messaging adherence medications chronic conditions.
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Up to 1 million lesbian, gay, bisexual, and transgender (i.e., sexual gender minority, SGM) individuals in the United States have histories of cancer. This medically underserved population is diverse, with complex sexualities identities, distinct health concerns. SGM persons experience disproportionate risks for, rates of, anal, breast, cervical, colorectal, endometrial, lung, prostate cancers, addition cancers affecting who undergone sex-reassignment. are linked by shared experiences...
Abstract Background: Preclinical evidence has shown that in xenograft models with estrogen receptor (ER)+/HER2+ breast cancer, signaling through the ER pathway can be enhanced presence of anti-HER2 treatment and lead to resistance. Concurrent targeting HER2 led efficacy complete tumor disappearance. We hypothesized endocrine therapy concurrently chemotherapy plus dual inhibition will not antagonistic overcome ER-mediated resistance result higher pCR as neoadjuvant ER+/HER2+ cancer. NRG...
Scientific advances have allowed the development of multiplex gene-panels to assess many genes simultaneously in women who tested negative for BRCA1/2. We examined correlates interest testing that confer modest and moderate breast cancer risk communication preferences from BRCA families. Female first-degree relatives patients BRCA1/2 mutations (N = 149) completed a survey assessing genetic preferences. Interest was high (70 %) even higher if results could guide risk-reducing behavior changes...
Harvest for Health is a home-based vegetable gardening intervention that pairs cancer survivors with Master Gardeners from the Cooperative Extension System. Initially developed and tested in Alabama, program was adapted different climate, growing conditions, population New Mexico. This paper chronicles feasibility, acceptability, preliminary efficacy of "Southwest Health". During nine-month single-arm trial, 30 survivor-Master Gardener dyads worked together to establish maintain three...
Abstract Background: Neoadjuvant aromatase inhibitor (AI) therapy would become a more acceptable alternative to chemotherapy if there was way identify AI-resistant cases early for triage alternate systemic treatment. We therefore conducted Phase 2 trial of post-menopausal patients with clinical stage or 3 ER+ (Allred Score 6 8) breast cancer who were re-biopsied 4 weeks after initiating neoadjuvant AI therapy. If the tumor Ki67 level > 10% (AI resistant) patient triaged either...
To assess the efficacy of University New Mexico Comprehensive Cancer Center's (UNMCCC's) breast cancer nurse navigator (BCNN) program in addressing gaps care for an underserved, rural, and economically disadvantaged population.54 navigated patients under BCNN 32 non-navigated whose began prior to start program.Surveys were administered anonymously during regularly scheduled appointments at UNMCCC.Navigated more strongly agreed that they prepared beginning treatment calls returned promptly,...
Few diet and physical activity evidence-based interventions have been routinely used in community settings to achieve population health outcomes. Adapting fit the implementation context is important desired results. Harvest for Health a home-based vegetable gardening intervention that pairs cancer survivors with certified Master Gardeners from Cooperative Extension Service ultimate goal of increasing consumption activity, improving functioning health-related quality-of-life. has potential...
6516 Background: Non-adherence to AI’s for breast cancer is common and increases risk of recurrence. Text messaging (TM) has been shown increase adherence medications chronic conditions. We conducted a multicenter randomized trial evaluate if TM reminders improve AI adherence. Methods: Patients taking an ≥30 days having ≥36 mos planned therapy were eligible. randomly assigned 1:1 receive either or NO-TM twice week 36 mos. Randomization was stratified by length time on prior ( < 12 (64%)...
PURPOSE: The numbers and types of oral oncolytics in oncology are expanding rapidly. Oral have serious adverse effects, pharmacist-driven patient education has the potential to reduce events. University New Mexico Comprehensive Cancer Center (UNM CCC) initiated a consent process for our minority, rural, economically disadvantaged population. PATIENTS AND METHODS: UNM CCC from August 2016 October 2018. metric measured via statistical control charts was percentage patients receiving oncolytic...
Many factors contribute to long wait times for patients on the day of their chemotherapy infusion appointments. Longer time leads nonoptimal care, increased costs, and decreased patient satisfaction. We conducted a quality improvement project reduce at Comprehensive Cancer Center.A multidisciplinary working group physicians, center nurses, pharmacists, information technology analysts, Chief Medical Officer, advocates formed group. Wait were analyzed, contributing identified....