- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Mechanical and Optical Resonators
- Molecular Junctions and Nanostructures
- Acoustic Wave Resonator Technologies
- Mosquito-borne diseases and control
- Advanced Nanomaterials in Catalysis
- Malaria Research and Control
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- Advanced MEMS and NEMS Technologies
Ernst Ruska Centre
2023-2024
Forschungszentrum Jülich
2021-2024
Diabetes patients suffer either from insulin deficiency or resistance with a high risk of severe long-term complications, thus the quantitative assessment level is highly desired for diabetes surveillance and management. Utilizing insulin-capturing aptamers may facilitate development affordable biosensors however, their rigid G-quadruplex structures impair conformational changes diminish sensor signals. Here we report on ratiometric, electrochemical aptasensor which achieved by hybridization...
Diabetes patients suffer either from insulin deficiency or resistance with a high risk of severe long-term complications, thus the quantitative assessment level is highly desired for diabetes surveillance and management. Here we report on ratiometric, electrochemical aptasensor which achieved by hybridization an insulin-capturing aptamer partially complementary ssDNA tagged anthraquinone (AQ) methylene blue (MB) redox probes, respectively. To improve durability aptasensor, capturing was...
In this work, we demonstrate that extremely thin strain-engineered K0.7Na0.3NbO3 (KNN) films are ideal candidates for highly sensitive and also potentially selective surface acoustic wave (SAW) sensor applications. The strength of the use these in SAW sensors is based on their piezoelectric properties thinness. latter leads to a strong concentration energy at very sensor's delay line generation higher harmonics with significant amplitudes. Thin epitaxial typically 30 nm thickness grown via...
Assessment tests for glycemic control of patients with diabetes mellitus commonly use blood glucose and glycated hemoglobin A1C (HbA1C) levels estimating acute long-term glycemia, respectively. Diabetes diet, as well treatment, are adapted accordingly also the risk diabetic complications can be estimated. Glycated human serum albumin (GHSA) has been proposed an alternative to HbA1C since it possesses a four times shorter lifespan its concentration is not affected by hemic diseases. Here,...