Xiaoshuang Li
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- vaccines and immunoinformatics approaches
- CAR-T cell therapy research
- Immune Cell Function and Interaction
Abstract A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety neoantigen-specific...
<div>Abstract<p>A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety...
<div>Abstract<p>A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety...
Supplementary Figure from Combination Neoantigen-Based Dendritic Cell Vaccination and Adoptive T-Cell Transfer Induces Antitumor Responses Against Recurrence of Hepatocellular Carcinoma
Supplementary Figure from Combination Neoantigen-Based Dendritic Cell Vaccination and Adoptive T-Cell Transfer Induces Antitumor Responses Against Recurrence of Hepatocellular Carcinoma