Xiaoshuang Li

ORCID: 0000-0003-2791-8818
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About
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Research Areas
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • vaccines and immunoinformatics approaches
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction

Abstract A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety neoantigen-specific...

10.1158/2326-6066.cir-21-0931 article EN Cancer Immunology Research 2022-04-27

<div>Abstract<p>A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety...

10.1158/2326-6066.c.6550752.v1 preprint EN 2023-04-04

<div>Abstract<p>A high rate of recurrence after curative therapy is a major challenge for the management hepatocellular carcinoma (HCC). Currently, no effective adjuvant available to prevent HCC recurrence. We designed personalized neoantigen-loaded dendritic cell vaccine and neoantigen-activated T-cell therapy, used it as treat 10 patients with who had undergone resection or radiofrequency ablation in first stage phase II trial (NCT03067493). The primary outcomes were safety...

10.1158/2326-6066.c.6550752 preprint EN 2023-04-04
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