A5014066082- Congenital heart defects research
- RNA modifications and cancer
- Innovations in Medical Education
- Epigenetics and DNA Methylation
- Radiology practices and education
- Global Health Workforce Issues
- Renal and related cancers
- Pregnancy and preeclampsia studies
- Attention Deficit Hyperactivity Disorder
- Diversity and Career in Medicine
- Heme Oxygenase-1 and Carbon Monoxide
- Global Cancer Incidence and Screening
- Respiratory viral infections research
- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Genomics and Rare Diseases
- Child and Adolescent Psychosocial and Emotional Development
- Pluripotent Stem Cells Research
- Inflammatory Biomarkers in Disease Prognosis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health, Environment, Cognitive Aging
- Circular RNAs in diseases
- Children's Physical and Motor Development
- Innovative Teaching Methods
- Education and Critical Thinking Development
University of Jeddah
2023-2025
Soliman Fakeeh Hospital
2024
King Faisal Specialist Hospital & Research Centre
2023
King Saud bin Abdulaziz University for Health Sciences
2023
King Abdullah International Medical Research Center
2023
Alfaisal University
2023
King Abdulaziz University
2023
King Fahad Hospital Jeddah
2023
University of Ottawa
2013-2018
McGill University
2011
BACKGROUND Flipped classrooms have gained popularity for their ability to improve educational outcomes by flipping traditional teaching approaches and fostering interactive learning settings. Our study aims assess the impact of these on medical students’ motivation, critical thinking skills, facilitation collaborative learning. METHODS A quasi-experimental was conducted involve quantitative surveys administered students both before after session. predefined questionnaire used 5 key outcomes:...
Pathology is the bridge between basic science and clinical practice. An inadequate perception of pathology leads to an incomplete understanding diseases, which consequently affects its management. This study aims identify medical students' perceptions in colleges around Saudi Arabia use their feedback improve teaching strategies. A validated online self-structured questionnaire form was distributed students years, including private governmental universities all regions Arabia. The comprised...
Abstract The Nkx2-5 gene codes for a transcription factor that plays critical role in heart development. Heterozygous mutations NKX2-5 both human and mice result congenital defects (CHDs). However, the molecular mechanisms by which these cause disease are still unknown. Recently, we have generated heterozygous mouse model of CHDs associated mutation R142C (Nkx2-5R141C/+ ortholog variant) developed septal conduction defects. This study R141C embryonic stem cell line mESCs) to vitro. We...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental commonly observed in children. Although the etiology of ADHD still unclear, many risk factors have been shown to increase prevalence ADHD, such as genetics, environmental factors, socioeconomic status, maternal smoking, and low birth weight.The current cross-sectional study aimed assess several associated with ADHD-diagnosed children aged 4-17 years using parent-reported data.An observational cross-section was conducted...
Abstract: Mutations in the hydroxymethylbilane synthase (HMBS) gene can lead to a deficiency of HMBS enzyme, allowing porphyrins accumulate toxic levels liver and other organs, leading acute intermittent porphyria (AIP). This case report describes medical journey 20-year-old female, previously good health, who experienced multiple hospitalizations clinic visits due severe abdominal pain episodes remained undiagnosed for over 6 years. Despite nonspecific nature these symptoms, suspicion...
Introduction The clinical significance of miR-877 and histidine-rich glycoprotein (HRG) in preeclampsia (PE) remains unknown. Bioinformatics analyses have identified HRG as a target for numerous micro RNAs. Based on novelty score, was selected this study to assess the placental serum samples from patients with PE, aim elucidating their potential role disease progression. Material methods This included 75 tissue obtained PE normal controls. group subdivided into mild severe cases. Relative...
Backgrounds Colorectal surgeons worldwide have differing opinions on the best way to handle rare cases of splenic flexure colon cancers (SFCs). Although majority reviews indicate no significant variation in oncological outcomes among three different procedure types used treat SFCs, still exhibit diversity their practices. This study determined treatment preferences colorectal Saudi Arabia. Methods A descriptive cross-sectional evaluated management handling SFC cases. We utilized a validated...
Abstract Background Understanding genetics is crucial for medical students, particularly in Saudi Arabia, where genetic disorders are prevalent owing to high rates of consanguineous marriages. This knowledge essential the early detection, prevention, and management disorders, incorporating genomics into patient care. study aimed assess current state among students interns across Arabia identify gaps genetics. Method A cross-sectional was conducted between August September 2023 involving 732...
Previous studies have found an association between maternal smoking and increased risk of attention deficit hyperactivity disorder (ADHD) in offspring. However, the prevalence smoking, secondhand smoke (SHS) exposure during pregnancy, ADHD children within Saudi Arabian context is not well-documented. Objective: To explore SHS pregnancy among mothers diagnosed with investigate to as a predictor subtypes. Methods: A cross-sectional study was conducted from December 1, 2022, February 28, 2023,...
Background: Rheumatoid arthritis is a severe inflammatory that causes irreversible damage to joints and bones, resulting in deformities disabilities. Population-based studies on the co-occurrence patients with rheumatoid are lacking despite shared mechanisms other autoimmune diseases. Objectives: This study aimed determine prevalence association of diseases among explore associations between treatment options for arthritis. Method: retrospective was conducted from 2019 2023 at King Fahad...
Background and objectives Surgical/anatomical pathologists study diseases to provide accurate diagnoses, identify pathogens, participate in treatment. However, there is a need for more surgical worldwide due low recruitment rates. One contributing factor the medical students’ interest knowledge about pathology as career option. Understanding perceptions pathologist jobs crucial future physicians, it influences collaboration with impacts patient care outcomes. This aims evaluate of...
Early detection of lung cancer through screening can improve outcomes; yet public knowledge, attitudes, and practices regarding in Saudi Arabia are limited.
Utilizing the GEPIA database, we analyzed The analysis revealed significant disparities in These findings suggest potential role of
This study explored the experiences of first-generation and non-first-generation medical students in Saudi Arabia regarding their education, career aspirations, attitudes toward school, perceived stress. We aimed to provide insights into struggles faced by students. cross-sectional was conducted with 485 participants, 77.9% whom were Data collected using a questionnaire adapted from Association American Medical Colleges (AAMC) analyzed chi-square Mann-Whitney tests. First-generation less...
Hemophilia A (HA) is an X-linked recessive disorder that results from mutations in the factor VIII gene (FVIII). Most affected patients are males due to inheritance of FVIII their mothers. Females mostly found be carriers unless they inherited mutation both parents. Obligate HA mothers whose sons with HA, or daughters who inherit fathers. possible carrier could any female has one more relatives her family. (HACs) present similar symptoms patients, including low level, and risk bleeding...
To investigate the geographic distribution of common cystic fibrosis (CF) variants in western and southern regions Saudi Arabia.A retrospective study was conducted on 69 patients diagnosed with CF at King Faisal Specialist Hospital & Research Center, Jeddah. Patient data were collected retrospectively between June 2000 November 2021. Various parameters considered, including patient demographic information, CFTR variants, respiratory cultures.We identified 26 CF, one novel variant that had...
Abstract We have established an in vitro model of the human congenital heart defect (CHD)–associated mutation NKX2.5 R141C . describe use hanging drop method to differentiate Nkx2.5 R141C/+ murine embryonic stem cells (mESCs) along with +/+ control cells. This allows us recapitulate early stages development tissue culture. also qRT‐PCR and immunofluorescence examine samples at different time points during differentiation validate our data. The vivo is a mouse line knock‐in same mutation....
Transmembrane Emp24 domain trafficking protein (TMED) 2, a member of the p24 family chaperones is involved in transport between ER and Golgi. TMED2 complexes with TMED7, TMED9 TMED10 required for normal levels these proteins. Loss Tmed2 results delayed abnormal development homozygous mutant mouse embryos placentas, loss TMED7 TMED10, decreased expression protein. In embryos, labyrinth layer placenta - site gas nutrient exchanges mother fetus fails to form. Formation depends on proper...