Menopause may augment age-dependent increases in arterial stiffness, with black women having greater progression midlife compared white women. We sought to determine whether and when experience changes stiffness relative the final menstrual period (FMP) these differ between Approach Results: evaluated 339 participants from SWAN (Study of Women's Health Across Nation) Heart Ancillary study Nation). Women had ≤2 carotid-femoral pulse-wave velocity (cfPWV) exams over a mean±SD 2.3±0.5 years...

Objective- HDL-C (high-density lipoprotein cholesterol) may not always be cardioprotective in postmenopausal women. HDL particles (HDL-P) via ion-mobility better reflect the antiatherogenicity of HDL. Objectives were (1) to evaluate associations and HDL-P with carotid intima-media thickness (cIMT) plaque separately jointly women; (2) assess interactions by age at time since menopause. Approach Results- Analysis included 1380 females from MESA (Multi-Ethnic Study Atherosclerosis; age:...

Whether changes in blood pressure (BP) over women's midlife are more driven by chronological aging or the menopause transition has been debated. We sought to determine whether women can be classified into distinct trajectory groups based on pattern and level of systolic BP (SBP), diastolic BP, pulse (PP), mean arterial (MAP) transition, assess menopause-related factors predict group measures.Participants were from SWAN (Study Women's Health Across Nation). Group-based modeling was used...

To characterize abdominal visceral adipose tissue (VAT) trajectory relative to the final menstrual period (FMP), and test whether menopause-related VAT accumulation is associated with greater average, common carotid artery intima-media thickness (cIMT) and/or internal (ICA-IMT).Participants were 362 women (at baseline: age was (mean ± SD) 51.1 2.8 y; 61% White, 39% Black) no cardiovascular disease from Study of Women's Health Across Nation Heart study. Women had up two measurements cIMT over...

Cytogenetics laboratory tests are among the most important procedures for diagnosis of genetic diseases, especially in area hematological malignancies. Manual chromosomal karyotyping methods time consuming and labor intensive and, hence, expensive. Therefore, to alleviate process analysis, several attempts have been made enhance karyograms. The current image enhancement is based on classical processing. This approach has its limitations, one which that it a mandatory application all...

Pathology is the bridge between basic science and clinical practice. An inadequate perception of pathology leads to an incomplete understanding diseases, which consequently affects its management. This study aims identify medical students' perceptions in colleges around Saudi Arabia use their feedback improve teaching strategies. A validated online self-structured questionnaire form was distributed students years, including private governmental universities all regions Arabia. The comprised...

Introduction: Substantial hormonal and adverse lipid changes have been reported within one-year interval of the final menstrual period (FMP) suggesting this as a critical time in midlife women. Significant structural vascular remodeling has documented during late peri-menopausal stage, stage characterized by amenorrhea for at least 3 months. Whether functional also accompany menopause transition occur FMP is not clear. Central arterial stiffness measured aortic pulse wave velocity (aPWV),...

<h3>Objectives:</h3> To investigate the long-term outcomes of differentiated thyroid cancer (DTC) and predictive factors for excellent incomplete responses to therapy on follow-up patients. <h3>Methods:</h3> A retrospective chart review analysis was carried out at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Demographic, histological, therapeutic data were collected from patients older than 13 years time diagnosis, with a minimum 18 months. Outcomes divided into excellent,...

AMA Samman A, Hanbazazh M, Samargandy S, Al-Maghrabi J. Expression of p16 protein in breast cancer. Polish Journal Pathology. 2024. doi:10.5114/pjp.2024.136028. APA Samman, A., Hanbazazh, M., Samargandy, S., & Al-Maghrabi, (2024). https://doi.org/10.5114/pjp.2024.136028 Chicago Abdulhadi, Mehenaz Saad and Jaudah Al-Maghrabi. "Expression cancer". Harvard MLA Abdulhadi et al. cancer." Pathology, Vancouver

Background and objectives Surgical/anatomical pathologists study diseases to provide accurate diagnoses, identify pathogens, participate in treatment. However, there is a need for more surgical worldwide due low recruitment rates. One contributing factor the medical students’ interest knowledge about pathology as career option. Understanding perceptions pathologist jobs crucial future physicians, it influences collaboration with impacts patient care outcomes. This aims evaluate of...

Introduction: Abdominal visceral adipose tissue (VAT) contributes to pathogenesis of cardiometabolic disease through endocrine and paracrine secretion adipocytokines. Midlife women experience redistribution towards increasing central adiposity. A few studies suggested a contribution the menopausal transition, but evidence is lacking characterize change in VAT relative time final menstrual period (FMP). We hypothesized that would non-linearly FMP with significant rise close FMP. Methods:...

Social media plays a major role in modern healthcare. However, little is known about physicians' experience as related to medical consultation through social media, such Twitter. This study aims characterize attitudes and perceptions toward consultations estimate the use of for purposes.The was conducted distribution electronic questionnaires physicians from different specialities. A total 242 healthcare providers responded questionnaire.Our results demonstrated that 79% received at least...

Several studies have reported increased glucose transporters (GLUT) expression in different cancer types, including breast cancer. The primary purpose of this study is to examine GLUT1 immunoexpression patients Saudi Arabia and determine its significance. examined the association between immunophenotype clinicopathological characteristics was analyzed retrospectively collected tissue samples (n = 578) from using immunohistochemistry. A total 311 (54%) cases expressed cytoplasmic...

Objective: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic in developed nations and independently associated with increased overall morality from all causes as well CVD. Growing evidence support that low serum 25-hydroxyvitamin D ((25OH)D) NAFLD. However, significant racial/ethnic differences exist 25(OH)D prevalence NAFLD: African Americans have lower than Caucasians, NAFLD higher Caucasians. We tested whether association between vary by race/ethnicity, adjusting...

where he focused his training on the epidemiology of CVD in midlife women.He published research that showed arterial stiffness and abdominal visceral adipose tissue increasing around menopause.In this issue Circulation Research, colleagues were able to show menopause transition is also a predictor accelerated increases blood pressure enjoys reading books social psychology practices woodworking as hobby.He can be found Twitter @dr_saadss.