A5005543219- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Congenital Diaphragmatic Hernia Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiomyopathy and Myosin Studies
- Tracheal and airway disorders
- Muscle Physiology and Disorders
- Cardiac pacing and defibrillation studies
- Anesthesia and Sedative Agents
- Atrial Fibrillation Management and Outcomes
- Mechanical Circulatory Support Devices
- Mitochondrial Function and Pathology
- Cardiovascular Conditions and Treatments
- Cardiovascular Issues in Pregnancy
- Pulmonary Hypertension Research and Treatments
- Kawasaki Disease and Coronary Complications
- Transplantation: Methods and Outcomes
- Congenital Anomalies and Fetal Surgery
- Congenital heart defects research
- Hemodynamic Monitoring and Therapy
The University of Texas Southwestern Medical Center
2012-2022
Children's Medical Center
2003-2021
Southwestern University
2021
Medical City Children's Hospital
2017
Southwestern Medical Center
2011-2016
The University of Texas at Austin
2002
University of Colorado Boulder
1997
Background — The Fontan procedure is the definitive operation for palliation of complex congenital heart disease with single-ventricle physiology. Fenestration circuit allows shunting deoxygenated blood to systemic circulation. This improved clinical outcomes patients who are at high risk poor results. However, it controversial whether fenestration beneficial standard-risk patients. Methods and Results prospective, randomized trial evaluated utility in standard preoperative profiles surgery....
OBJECTIVE. The physiologic responses to chloral hydrate sedation in the setting of a pediatric echocardiography laboratory have not been well documented; neither has population at risk identified adequately. purpose this study was describe sedation, report occurrence adverse events, and identify any factors that predicted these events children who underwent for our institution. METHODS. We analyzed retrospectively 1095 patients were sedated echocardiography. Vital signs oxygen saturations...
Subclinical cardiotoxicity occurs in childhood cancer survivors following moderate and high anthracycline doses. However, less is known about the subclinical changes left ventricular (LV) structure that occur after very low doses of ≤ 100 mg/m(2). This study was designed to assess LV function key structural parameters anthracycline.Conventional 2-dimensional echocardiograms with Doppler were obtained 91 exposed mg/m(2), an average 9.8 years from diagnosis. measurements converted into...
Objective: Optimal cannula position is essential during extracorporeal membrane oxygenation (ECMO). We hypothesize that echocardiography superior to chest radiography in diagnosing abnormal ECMO. Design: Retrospective. Setting: Pediatric hospital. Patients: 100 pediatric patients requiring Measurements and Main Results: reviewed the medical records of all ECMO (n = 100), including reports echocardiograms 326), years 2002–2004. Of 91 who had while on ECMO, 33 at least 1 echocardiogram for...
Incidence of thrombosis after initial stage 1 single-ventricle palliation is high. Most centers use aspirin as an antiplatelet agent to prevent in surgically placed shunts. We hypothesize there a significant incidence resistance infants and this can be overcome by increased dose.This prospective observational study 20 patients with physiology who required controlled source pulmonary blood flow (Norwood/Sano, Norwood/Blalock-Taussig [BT] shunt or BT alone). Aspirin was determined using...
Previous studies have demonstrated that environmentally or genetically induced changes in the intracellular proteins compose cytoskeleton can contribute to heart failure. Because neonatal right ventricular myocytes are immature and process of significant cytoskeletal change, we hypothesized they may be particularly susceptible pressure stress. Newborn calves exposed hypobaric hypoxia (barometric = 430 mmHg) for 14 days developed severe pulmonary hypertension (pulmonary arterial 101 ± 6 vs....
Nemaline myopathy is a congenital nonprogressive skeletal muscle disorder with characteristic rod body formation in the fibers. Cardiac involvement nemaline rare, although both dilated and hypertrophic cardiomyopathy have been reported. We describe an infant diagnosed hypotonia on first day of life. Muscle biopsy confirmed at 3 weeks age. The diagnosis precluded consideration heart transplantation, thus shifting focus to comfort care. This earliest presentation reported literature setting...
transesophageal echocardiography (TEE) is the gold standard for diagnosis of a patent foramen ovale in adults. In children, acoustic windows on transthoracic (TTE) are better than adults; thus, an invasive TEE may not be necessary. Our goal was to assess validity TTE with agitated saline injection children using as standard.fifty consecutive pediatric patients >1 year age referred were prospectively enrolled. Imaging included 2-dimensional, color Doppler, and contrast injections without...
An unruptured sinus of Valsalva aneurysm is usually asymptomatic, and a rare, often incidental echocardiographic diagnosis. Its presentation in the neonatal period extremely rare. We describe this finding neonate with hypoplastic left heart syndrome, which has not been previously reported literature. This constellation findings may have important clinical implications regards to medical management surgical options.
Initial signs of cardiac dysfunction caused by Duchenne muscular dystrophy are usually detected during adolescence. However, decreased physical activity can allow better tolerance function. Mild myocardial secondary to ischemic or idiopathic cardiomyopathy is accompanied elevation plasma levels norepinephrine and atrial natriuretic factor. This considered an adaptation maintain adequate perfusion. We evaluated neurohormone in 17 adolescents (median age 14 years) with different degrees...