A5002263024- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Metastasis and carcinoma case studies
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Colorectal and Anal Carcinomas
- Gastrointestinal disorders and treatments
- Minimally Invasive Surgical Techniques
- Helicobacter pylori-related gastroenterology studies
- Genetic factors in colorectal cancer
- Colorectal Cancer Treatments and Studies
- Peptidase Inhibition and Analysis
- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Diverticular Disease and Complications
- Glycosylation and Glycoproteins Research
- COVID-19 and healthcare impacts
- Galectins and Cancer Biology
- Biliary and Gastrointestinal Fistulas
- Omental and Epiploic Conditions
- Protease and Inhibitor Mechanisms
- Spectroscopy Techniques in Biomedical and Chemical Research
- Management of metastatic bone disease
Oita University
2016-2025
The Japanese Society of Gastroenterological Surgery
2021-2024
Oita University Hospital
2017
Fundación Juan March
2010
May Institute
2010
Niigata University
2005
In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedures have been standardized, and safety efficacy of surgery evaluated. accordance with social acceptance as less invasive type number has increased all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. Notably, technical skills certification system surgeons established by JSES to train instructors on how teach...
Abstract Aim This study aimed to evaluate the association between surgeons certified via Endoscopic Surgical Skill Qualification System (ESSQS) of Japan Society for Surgery (JSES) and surgical outcomes laparoscopic distal gastrectomy (LDG) low anterior resection (LLAR). Methods Japanese National Clinical Database data on patients undergoing LDG LLAR 2014‐2016 were analyzed retrospectively. The proportion cases performed by ESSQS‐certified was calculated each procedure, clinicopathological...
Abstract This article reports the results of 16th National Survey conducted by Japan Society for Endoscopic Surgery (JSES) 2020 and 2021. Laparoscopic cholecystectomy was first introduced to in 1990 has rapidly become popular because its minimally invasive nature. Since then, number objective organs indications laparoscopic surgery have gradually expanded. In 2021, 290 787 patients underwent endoscopic all surgical domains. Of these, 124 614, 110 757, 23 156, 21 771, 6543, 2614, 535, 465,...
Abstract In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedure has been standardized, and safety usefulness of surgery have evaluated. accordance with social acceptance as less‐invasive number procedures increasing all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. For example, JSES established technical skills certification system surgeons to train...
Open gastrectomy is associated with increased morbidity and a longer hospital stay than laparoscopically assisted gastrectomy. The aim of this study was to clarify the value distal (LDG) in elderly, whom co-morbid disease generally more common.Forty-five elderly patients (aged 70 years or more) 57 younger who underwent LDG, 28 open (ODG) for early gastric cancer between January 1994 April 2003 were studied. Demographics postoperative outcomes compared.: Co-morbidity common LDG (25 45 versus...
Abstract Background The impact of obesity on colon cancer remains unclear. Very few studies surgery have analyzed body mass index (BMI) as a continuous variable, with no such reports from Japan. This study examined the association between BMI variable and short‐ long‐term outcomes laparoscopic for obese patients. Methods Obese (BMI ≥25 kg/m 2 ) patients who underwent radical Stage II/III at 46 participating centers 2009 to 2013 were included. Associations by univariate multivariate...
ABSTRACT Objectives: The relationship between surgery and gut microbiota has recently attracted attention, however changes of the composition are still unclear. aim this study was to investigate altered in patients with colorectal cancer perioperative period. Methods: This prospective, single-center, observational cohort included 48 who underwent radical at Oita University Hospital. Stool samples were collected on day 2 days before surgery, postoperative 1, 3, 7, after 1 month year. primary...
We examined which, and how many, mucin markers are necessary to define the phenotypes of gastric cancers, re‐evaluated incidence their whether minute carcinomas arise as unclassified type. Well‐differentiated‐type ( n = 33) measuring ≤5 mm were using human (HGM) MUC5AC, MUC6 M‐GGMC‐1 (or paradoxical concanavalin A type III (Con A)), MUC2 CD10 stains, a new method separate previous intestinal into small The classified gastric, gastrointestinal, intestinal, types. MUC5AC or HGM, MUC6, MUC2,...
Abstract Background The COVID‐19 outbreak made conventional medical care impossible, forcing changes in both healthcare providers and patients. In Japan, infection began spreading earnest 2020 exploded 2021. There was concern that the impact of 2021 would differ from 2020. We aimed to clarify on mortality anastomotic leakage laparoscopic surgery for gastric cancer rectal Japan using National Clinical Database (NCD). Methods collected data patients who underwent distal gastrectomy (LDG) low...
Background and Aim We have focused on sodium alginate ( SA ) solution as a potential submucosal injection material for endoscopic dissection ESD ). A previous had high viscosity problems such difficult handling. After its properties were adjusted, was examined in vitro clinical safety evaluated. Methods With 0.4% hyaluronate SH control, catheter injectability mucosa‐elevating capacity of 0.3–0.8% solutions Next, 0.6% used 10 patients with early gastric cancer prospective study. Results...
Abstract Background Recently, colorectal cancer has increased in elderly patients worldwide, with laparoscopic surgery increasing cancer. However, whether is an optimal procedure for the remains unclear. This study aimed to verify safety and curability of ≥80 years old. Methods Patients undergoing curative from 2006 2014 were enrolled classified into aged (LAC-E) group, open (OC-E) non-elderly (LAC-NE) group. Short- long-term outcomes compared between these groups. Results The LAC-E, OC-E,...
A 1.296-to-5.184 Gb/s transceiver with 2.4 mW/(Gb/s) burst-mode CDR using a dual-edge injection-locked oscillator is fabricated in 40 nm CMOS. The chip operates over range of 1.296 to 5.184 Gb/s. proposed locks less than 20b and features continuous-rate capability, twice the power efficiency previously reported CDRs.
This study aimed to evaluate the impact of coronavirus disease (COVID-19) pandemic on elective endoscopic surgeries in Japan using National Clinical Database.
Whether gastrectomy with D2 lymphadenectomy improves survival of patients advanced gastric cancer (AGC) remains controversial. Few studies have described the pathological features AGC metastatic suprapancreatic lymph nodes (LN), which are target lymphadenectomy. This study therefore aims to clarify prognosis and clinical including number location LN in LN. 406 AGC, who underwent from 1982 2007 at Oita University, were reviewed retrospectively regard presence or absence The factors associated...
Whether a laparoscopic procedure can contribute to the improvement of clinical outcomes in obese patients with stage II/III rectal cancer compared an open remains unclear.This study evaluated technical and oncological safety surgery versus (body mass index [BMI] ≥25 kg/m2) cancer.Data were collected from pathological analyzed. Operations performed via or 2009 2013. A comparative analysis was after applying propensity score matching two cohorts (laparoscopic group group). The primary endpoint...
Abstract In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedures have been standardized, and safety efficacy of surgery evaluated. accordance with social acceptance as less invasive type number has increased all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. Notably, technical skills certification system surgeons established by JSES to train instructors on...
ObjectiveAlthough pre-operative chemoradiation therapy for advanced lower rectal cancer is a controversial treatment modality, it increasingly used in combination with surgery. Few studies have considered the of followed by laparoscopic surgery locally cancer; therefore, this study aimed to assess usefulness therapeutic combination.
Background and Objectives:There is no standardized method of reconstruction in laparoscopic proximal gastrectomy (LPG). We present a novel technique with long, narrow gastric tube LPG for early cancer (EGC).Methods:During the procedure, upper part stomach fully mobilized perigastric suprapancreatic lymphadenectomy, then abdominal esophagus transected. After minilaparotomy created, entire pulled outside. A (20 cm 3 wide) created linear stapler. The formed into cobra head shape esophagogastric...
As the incidence of gastric cancer increases in elderly patients worldwide, laparoscopic gastrectomy (LG) for with is also increasing. However, whether LG an optimal surgical modality remains unclear. This study aimed to evaluate technical and oncological safety ≥ 80 years old cancer.Patients who received curative from 2003 2015 were enrolled study. They divided into aged over (LG-E) group, open (OG) (OG-E) non-elderly < (LG-NE) group. Patients' demographics short- long-term outcomes, such...
Mutations in RAS or BRAF are associated with poor prognosis and resistance to epidermal growth factor receptor (EGFR)-targeted therapy colorectal cancer (CRC). Despite their common ability activate downstream genes such as MEK ERK, the therapeutic benefit of inhibitors for patients RAS/BRAF mutant CRC is limited, highlighting need biomarkers predict efficacy inhibition. Previously, we reported that a change phosphorylation ribosomal protein S6 (pS6) after inhibition was significantly...