A5088659944- Fatty Acid Research and Health
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Risk Factors
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Function and Risk Factors
- Nutritional Studies and Diet
- Blood Pressure and Hypertension Studies
- Cancer, Lipids, and Metabolism
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Disease Prevention
- Cardiac Health and Mental Health
- Adipokines, Inflammation, and Metabolic Diseases
- Sex and Gender in Healthcare
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Atherosclerosis and Cardiovascular Diseases
- Child Nutrition and Water Access
- Cardiac Valve Diseases and Treatments
- Medication Adherence and Compliance
Johns Hopkins Medicine
2020-2024
Johns Hopkins University
2020-2024
Jahra Hospital
2024
Beth Israel Deaconess Medical Center
2017-2023
University of Baltimore
2022
Harvard University
2017-2019
Kuwait University
2012-2014
Background Although statins reduce cardiovascular events, residual risk remains. Therefore, additional modalities are needed to risk. We evaluated the effect of eicosapentaenoic acid and docosahexaenoic in pharmacologic doses added statin treatment on coronary artery plaque volume. Methods Results A total 285 subjects with stable disease were randomized omega‐3 ethyl‐ester (1.86 g 1.5 daily) or no (control) for 30 months. Coronary volume was assessed by computed tomographic angiography. Mean...
Abstract Inflammation in arterial walls leads to coronary artery disease (CAD). We previously reported that a high omega‐3 fatty index was associated with prevention of progression atherosclerosis, chronic inflammation the wall. However, mechanism such benefit is unclear. The two main acids, eicosapentaenoic acid (EPA) and docosahexaenoic (DHA), are precursors specialized pro‐resolving lipid mediators (SPMs)–resolvins maresins–which actively resolve inflammation. To explore whether SPMs...
Background Albuminuria is a marker of inflammation and an independent predictor cardiovascular morbidity mortality. The current study evaluated whether eicosapentaenoic acid ( EPA ) docosahexaenoic DHA supplementation attenuates progression albuminuria in subjects with coronary artery disease. Methods Results Two‐hundred sixty‐two stable disease were randomized to either Lovaza (1.86 g 1.5 daily) or no (control) for 1 year. Percent change urine albumin‐to‐creatinine ratio ACR was compared....
Aims Our aim was to explore sex differences and inequalities in terms of medical management cardiovascular disease (CVD) outcomes a low/middle-income country (LMIC), where reports are scarce. Methods We examined presentation, clinical 21 374 patients presenting with acute coronary syndrome (ACS) Kerala, India enrolled the Acute Coronary Syndrome Quality Improvement Kerala trial. The main were rates in-hospital 30-day major adverse events (MACEs) defined as composite death, reinfarction,...
Article: Efficacy and Safety of Pharmacoinvasive Strategy Compared to Primary Percutaneous Coronary Intervention in the Management ST-Segment Elevation Myocardial Infarction: A Prospective Country-Wide Registry
Limited data exists on the risk factor profile and outcomes of young patients suffering their first acute myocardial infarction (AMI).We examined 1562 Gulf-Arabs without prior cardiovascular disease presenting with AMI enrolled in Gulf COAST prospective cohort. Clinical characteristics were compared ≤50 years age (young) vs. >50 (older). Associations between group in-hospital adverse events (re-infarction, heart failure, cardiogenic shock, cardiac arrest, stroke, death) or post-discharge...
Background Randomized trials of pharmacologic strength omega-3 fatty acid (n3-FA)-based therapies suggest a dose-dependent cardiovascular benefit. Whether blood n3-FA levels also mediate safety signals observed in these trials, such as increased bleeding and atrial fibrillation (AF), remains uncertain. We hypothesized that higher baseline would be associated with incident AF events MESA (Multi-Ethnic Study Atherosclerosis), which included population free clinical disease at baseline. Methods...
Objectives: To assess the level of nutritional knowledge (NK) among male Kuwaiti college students and to correlate NK scores with different domains. Methods: A random sample 378 was asked answer a questionnaire regarding socio-demographic health-related factors questions assessing their on Height weight were measured. Results: low. sodium carbohydrates highest, where those protein cholesterol lowest. Only older age, healthy dental status, high academic achievement in school associated NK....
Background Residual risk of cardiovascular events and plaque progression remains despite reduction in low-density lipoprotein cholesterol. Factors contributing to residual remain unclear. The authors examined the role eicosapentaenoic acid docosahexaenoic coronary regression its predictors. Methods Results A total 240 patients with stable artery disease were randomized plus (3.36 g/d) or none for 30 months. Patients stratified by fatty measured computed tomographic angiography. Cardiac...
In 2019, Preventive Cardiology welcomed many exciting discoveries that improve our ability to reduce the burden of cardiovascular disease (CVD) nationwide. Not only did 2019 further clarify how various environmental exposures and innate acquired risk factors contribute development CVD, but it also provided new guidelines therapeutics more effectively manage existing CVD. Cardiovascular prevention requires prioritization early effective detection CVD in order implement aggressive lifestyle...
Introduction: Microalbuminuria is a marker of generalized endothelial dysfunction, key step in the pathogenesis coronary artery disease (CAD). It also an independent predictor cardiovascular morbidity and mortality. Angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) therapy considered standard care to attenuate progression albuminuria diabetic patients. Hypothesis: Omega-3 fatty acids (FAs) supplementation will microalbuminuria subjects with stable CAD....
Background: Despite cardiovascular disease being the leading cause of death in India, limited data exist regarding factors associated with outcomes patients diabetes who suffer acute myocardial infarction (AMI). Methods: We examined 21,374 AMI enrolled ACS QUIK trial. compared in-hospital and 30-day major adverse cardiac events including death, re-infarction, stroke, or bleeding those without diabetes. The associations between were adjusted for presentation management using logistic...