A5073885433- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Aquaculture Nutrition and Growth
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Genetics and Reproduction
- Immune Response and Inflammation
- Crustacean biology and ecology
- Neurobiology and Insect Physiology Research
- Reproductive biology and impacts on aquatic species
- Physiological and biochemical adaptations
- interferon and immune responses
- Marine Bivalve and Aquaculture Studies
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- NF-κB Signaling Pathways
- CRISPR and Genetic Engineering
- Environmental Toxicology and Ecotoxicology
- Genetic diversity and population structure
- RNA modifications and cancer
- Gender Studies in Language
- Insect Resistance and Genetics
- Cancer, Hypoxia, and Metabolism
- Circular RNAs in diseases
- Vibrio bacteria research studies
- Sperm and Testicular Function
Fujian Agriculture and Forestry University
2016-2025
Shanxi Medical University
2012-2025
Changzhou University
2024-2025
Beijing Municipal Ecological and Environmental Monitoring Center
2021-2024
Nantong University
2024
Ningxia University
2011-2024
Zunyi Medical University
2023-2024
Hebei Medical University
2024
Second Hospital of Hebei Medical University
2024
Fudan University
2019-2023
The green mud crab (Scylla paramamosain) is the most prevalent crustacean on southeast coast of China. molecular regulatory mechanism sex determination and gonadal differentiation in this species has received considerable attention recent years because huge differences--both biological economic--between male female crabs. In study, next-generation sequencing technology was used to develop deep-coverage transcriptomic data for testis ovary S. paramamosain.A total 365,116 reads (testis...
Long non-coding RNAs (lncRNAs) are crucial in the invasion, angiogenesis, progression, and metastasis of hepatocellular carcinoma (HCC). The lncRNA MYLK-AS1 promotes growth invasion HCC through EGFR/HER2-ERK1/2 signaling pathway. However, clinical significance still needs to be further determined.Bioinformatic analysis was performed determine potential relationship among MYLK-AS1, miRNAs mRNAs. A total 156 samples normal liver paired tissues from patients were used evaluate expression by...
Coccidiosis is an important parasitic disease of poultry with great economic importance. Due to drug resistance issues, the study was conducted investigate how probiotics (Lactobacillus plantarum or L. plantarum) affected oocysts per gram feces (OPG), fecal scores, feed conversion ratio (FCR), immunomodulatory effect in terms cell-mediated and humoral immune response. Serum chemistry (ALT, AST, LDH, creatinine) measured different treated chicken groups. mRNA expression levels antioxidant...
Rutin inhibited amylin aggregation, amylin-induced neurocytotoxicity, and decreased the production of ROS, NO, GSSG, malondialdehyde pro-inflammatory cytokines.
The red-spotted grouper Epinephelus akaara (E. akaara) is one of the most economically important marine fish in China, Japan and South-East Asia a threatened species. species also considered good model for studies sex inversion, development, genetic diversity immunity. Despite its importance, molecular resources E. remain limited no reference genome has been published to date. In this study, we constructed chromosome-level by taking advantage long-read single-molecule sequencing de novo...
Lipid accumulation in ovaries is essential for reproductive success decapods. Understanding of the mechanism ovarian lipid still its infancy. In this study, we investigated compositions and hepatopancreas throughout vitellogenesis hemolymph late-vitellogenic stage mud crab Scylla paramamosain. Total content consecutively increased from early to late stage, main accumulated lipids were phosphatidylcholine (PC), alkenylglycerophosphoethanolamine (alkenyl-PE), triacylglycerol (TG), cholesteryl...
In gnathostomes, chemosensory receptors (CR) expressed in olfactory epithelia are encoded by evolutionarily dynamic gene families encoding odorant (OR), trace amine-associated (TAAR), V1Rs and V2Rs. A limited number of OR-like sequences have been found invertebrate chordate genomes. Whether these arose basal or advanced vertebrates has not resolved because examined systematically agnathan Petromyzon is the only extant jawless vertebrate whose genome sequenced. Known to be exquisitely...
Background De novo assembly of non-model organism’s transcriptomes has recently been on the rise in concert with number de transcriptome software programs. There is a knowledge gap as to what assembler or k-mer strategy best for construction an optimal assembly. Additionally, there lack consensus which evaluation metrics should be used assess quality assemblies. Result Six different strategies were evaluated from four assemblers. The Trinity was its default 25 single value while Bridger,...
Three new aspochracin-type cyclic tripeptides, sclerotiotides M–O (1–3), together with three known analogues, sclerotiotide L (4), F (5), and B (6), were obtained from the ethyl acetate extract of fungus Aspergillus insulicola HDN151418, which was isolated an unidentified Antarctica sponge. Spectroscopic chemical approaches used to elucidate their structures. The absolute configuration side chain in compound 4 elucidated for first time. Compounds 1 2 showed broad antimicrobial activity...
Objective: To explore the intimal injury of two kinds hemostatic clips under different clamping forces, and to optimize verify calculation formula minimum occlusion force (MOF), so as provide theoretical basis for selecting appropriate reduce vascular injury. Methods: A total 96 male SD rats with body weight ranging from 280 g 300 (Animal Experimental Center Shanxi Medical University) were randomly assigned metal clip group (n=48) disposable by random number table method. Each was further...
Glucose transporters (GLUTs) have been implicated in adaptive and survival responses to hypoxic stress mammals. In fish, the expression regulation of GLUT relation hypoxia remains unexplored. Here we describe identification a hypoxia‐responsive glucose transporter gene ( gcGLUT ) corresponding full‐length cDNA from grass carp. The spans ≈ 11 kb genomic sequence consists 12 exons introns, an open reading frame (ORF) 1599 bp encoding polypeptide 533 amino acids, with predicted molecular mass...
Summary Growth and fatness are economically important traits in pigs. In this study, a genome scan was performed to detect quantitative trait loci (QTL) for 14 growth related body weight, backfat thickness fat weight large‐scale White Duroc × Erhualian F 2 intercross. A total of 76 genome‐wide significant QTL were mapped 16 chromosomes. The most found on pig chromosome (SSC) 7 with unexpectedly small confidence intervals ∼2 cM, providing an excellent starting point identify causal variants....
Xiphophorus models are important for melanoma, sex determination and differentiation, ovoviviparity evolution. To gain a global view of the molecular mechanism(s) whereby gene expression may influence sexual dimorphism in to develop database future studies, we performed large-scale transcriptome study.The 454-FLX massively parallel DNA sequencing platform was employed obtain 742,771 721,543 reads from 2 normalized cDNA libraries generated whole adult female male X. maculatus Jp 163 A,...