Sofia Prates da Cunha de Azevedo

ORCID: 0000-0003-2814-0163
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About
Contact & Profiles
Research Areas
  • Genomics and Rare Diseases
  • Epilepsy research and treatment
  • Genetics and Neurodevelopmental Disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Respiratory viral infections research
  • Facial Nerve Paralysis Treatment and Research
  • Social and Economic Solidarity
  • Vitamin D Research Studies
  • Neuroscience of respiration and sleep
  • Neonatal Respiratory Health Research
  • Botulinum Toxin and Related Neurological Disorders
  • Interpreting and Communication in Healthcare
  • Parkinson's Disease and Spinal Disorders
  • Cancer Immunotherapy and Biomarkers
  • Glioma Diagnosis and Treatment
  • Hedgehog Signaling Pathway Studies
  • Psoriasis: Treatment and Pathogenesis
  • Education Pedagogy and Practices
  • Science and Education Research
  • Ophthalmology and Eye Disorders
  • Rheumatoid Arthritis Research and Therapies
  • Healthcare Systems and Public Health
  • Otolaryngology and Infectious Diseases
  • Neuroendocrine Tumor Research Advances
  • Diabetes Treatment and Management

Administração Regional de Saúde de Lisboa e Vale do Tejo
2024

Pontifícia Universidade Católica do Rio Grande do Sul
2022-2024

Hospital de Santo António
2024

Instituto do Cérebro
2023

Centro Hospitalar do Baixo Vouga
2022-2023

Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2023

Introduction Immunotherapy has a crucial role in the current treatment of multiple malignancies. Albeit described as rare, new onset autoimmune diabetes is potentially life-threatening complication programmed cell death-1 (PD-1) inhibitors, such pembrolizumab, and its predisposing factors pathological mechanism are yet to be clarified. Case Report We present case 72-year-old man with high-grade bladder carcinoma undergoing pembrolizumab treatment. He had no personal or family history...

10.1177/10781552241255699 article EN Journal of Oncology Pharmacy Practice 2024-05-20

Abstract Background Focal cortical dysplasia (FCD) is a malformation of development that causes medical refractory seizures, and one the main treatments may be surgical resection affected area brain. People by FCD present with seizures variable severity since childhood. Despite many available, only surgery can offer cure. The pathophysiology disease not yet understood; however, it known several gene alterations play role. WNT/β-catenin pathway closely related to control balance cell...

10.1186/s12883-023-03394-1 article EN cc-by BMC Neurology 2023-09-26

Background & Aims: Control of pulmonary exacerbations (PEs) is highly important in the treatment cystic fibrosis (CF).Given evidence extra skeletal properties vitamin D, this study aimed to evaluate effect supplementation with an dose D on CF PEs.Methods: This a randomized crossover clinical trial conducted Brazil.Subjects were randomly allocated receive (5,000-10,000IU/day, liquid, or gelatin capsules) followed by standard (400-2,000IU/day D), for three months, 9-month washout separating...

10.1016/j.nutos.2024.02.006 article EN cc-by-nc-nd Clinical Nutrition Open Science 2024-02-15

Type 2 diabetes poses a significant health challenge in Portugal, increasing the susceptibility to complications/comorbidities such as hypertension, obesity, and cardiovascular (CV) disease. This study aimed evaluate prevalence of type diabetes-related vascular their pharmacological management Portugal.

10.1016/j.repc.2024.04.011 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2024-07-01

Oromandibular dystonia is a focal characterized by involuntary movements of the jaw, oropharynx, lips, and tongue. The diagnosis oromandibular clinical can be complex. For effective treatment, it essential to understand its underlying etiology. A 70-year-old man was referred our center with Meige's syndrome, which had been present for five half years, receiving botulinum toxin-A (BoNT-A) injections. Upon physical examination, he exhibited dystonia, score 177 points on Dystonia Rating Scale...

10.7759/cureus.47248 article EN Cureus 2023-10-18

<title>Abstract</title> <bold>Background:</bold>Focal cortical dysplasia (FCD) is a malformation of development that causes medical refractory seizures, and one the main treatment may be surgical resection affected area brain. People by FCD present with seizures variable severity since childhood. Despite many treatments available, only surgery can offer cure. The pathophysiology disease not yet understood;however, it known several gene alterations play role. WNT/β-catenin pathway closely...

10.21203/rs.3.rs-2375373/v1 preprint EN cc-by Research Square (Research Square) 2022-12-28
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