A5008596041- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Environmental Justice and Health Disparities
- Toxic Organic Pollutants Impact
- Carcinogens and Genotoxicity Assessment
- Health Systems, Economic Evaluations, Quality of Life
- Health, Environment, Cognitive Aging
- Climate Change and Health Impacts
- Per- and polyfluoroalkyl substances research
- Heavy Metal Exposure and Toxicity
- Vehicle emissions and performance
- Environmental and Social Impact Assessments
- Birth, Development, and Health
- Economic and Environmental Valuation
- Early Childhood Education and Development
- Child Nutrition and Water Access
- Chemical Safety and Risk Management
- Food Security and Health in Diverse Populations
- Climate Change Policy and Economics
- Heavy metals in environment
- Air Quality Monitoring and Forecasting
- Noise Effects and Management
- Indoor Air Quality and Microbial Exposure
- Animal testing and alternatives
- Data Visualization and Analytics
University of Maryland, Baltimore
2025
Johns Hopkins University
2012-2025
Boston College
2025
Independent Sector
2022-2023
Fredericksburg Independent School District
2023
Environmental Protection Agency
2009-2019
JDSU (United States)
2016
Office of Policy
1998-2013
University of California, San Francisco
2012
Universidad Católica de Santa Fe
2012
Background: The Navigation Guide methodology was developed to meet the need for a robust method of systematic and transparent research synthesis in environmental health science. We conducted case study review support proof concept method.Objective: applied determine whether developmental exposure perfluorooctanoic acid (PFOA) affects fetal growth humans.Methods: first 3 steps human epidemiological data: 1) specify question, 2) select evidence, 3) rate quality strength evidence. protocol,...
Prenatal exposure to mercury has been associated with adverse childhood neurologic outcomes in epidemiologic studies. Dose-response information for this relationship is useful estimating benefits of reduced exposure.We estimated a dose-response between maternal body burden and subsequent decrements intelligence quotient (IQ), using Bayesian hierarchical model integrate data from three studies.Inputs the consist coefficients studies conducted Faroe Islands, New Zealand, Seychelles Islands. IQ...
Phthalate diesters have been shown to be developmental and reproductive toxicants in animal studies. A recent epidemiologic study showed certain phthalates significantly associated with reduced anogenital distance human male infants, the first evidence of subtle effects infants exposed prenatally phthalates. We used two previously published methods estimate daily phthalate exposures for four whose urinary metabolites were statistically 214 mother-infant pairs [di-n-butyl (DnBP) , diethyl...
Abstract The manufacture and production of industrial chemicals continues to increase, with hundreds thousands chemical mixtures used worldwide, leading widespread population exposures resultant health impacts. Low-wealth communities color often bear disproportionate burdens exposure impact; all compounded by regulatory delays the detriment public health. Multiple authoritative bodies scientific consensus groups have called for actions prevent harmful via improved policy approaches. We...
Occupational and toxicological studies have demonstrated adverse health effects from exposure to toxic air contaminants. Data on outdoor levels of contaminants not been available for most communities in the United States, making it difficult assess potential human general population exposures. Emissions data stationary mobile sources are used an atmospheric dispersion model estimate concentrations 148 each 60,803 census tracts contiguous States 1990. Outdoor toxics were compared previously...
Tracking incidence or prevalence of diseases and using that information to target interventions is a well-established strategy for improving public health. The need track environmentally mediated chronic increasingly recognized. Trends in childhood illnesses are 1 element framework children's environmental health indicators, which also includes trends contaminants the environment concentrations bodies children their mothers. This article presents data on 3 groups important disorders seem be...
Background: The National Academies recommended risk assessments redefine the traditional noncancer Reference Dose (RfD) as a probabilistically derived risk-specific dose, framework for which was recently developed by World Health Organization (WHO). Objectives: Our aim to assess feasibility and implications of replacing RfDs with probabilistic estimates human dose associated an effect magnitude M population incidence I (HDMI). Methods: We created comprehensive, curated database from animal...
Of the 188 hazardous air pollutants (HAPs) listed in Clean Air Act, only a handful have information on human health effects, derived primarily from animal and occupational studies. Lack of consistent monitoring data ambient toxics makes it difficult to assess extent low‐level, chronic, exposures HAPs that could affect health, limits attempts prioritize evaluate policy initiatives for emissions reduction. Modeled outdoor HAP concentration estimates U.S. Environmental Protection Agency's...
Relatively little is known about the spectrum of health effects, and scope level ambient air concentrations those pollutants regulated under Clean Air Act as "hazardous pollutants". The U.S. Environmental Protection Agency's (USEPA) Cumulative Exposure Project uses currently available emissions inventories, from a variety source types, an atmospheric dispersion model to provide estimates for 148 hazardous (HAPs) in over 60,000 census tracts year 1990. This paper hazard information provides...
The Clean Air Act identifies 189 hazardous air pollutants (HAPs), or "air toxics," associated with a wide range of adverse human health effects. U.S. Environmental Protection Agency has conducted modeling study the Assessment System for Population Exposure Nationwide (ASPEN) to gain greater understanding spatial distribution concentrations these HAPs resulting from contributions multiple emission sources. estimates year 1990 long-term outdoor 148 toxics each census tract in continental...
Analyses of the Third National Health and Nutrition Examination Survey (NHANES III) in 1988 to 1994 found an association increasing blood lead levels <10 μg/dL with a higher risk cardiovascular disease (CVD) mortality. The potential need correct for hematocrit/hemoglobin adjust biomarkers other metals, example, cadmium iron, had not been addressed previous NHANES III-based studies on lead-CVD mortality association. We analyzed 1999 2010 data 18,602 participants who measurement, were ≥40...
Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject few legal or policy constraints. A revamping of law and restructuring the chemical industry required.
Environmental exposures, including widespread industrial pollution, impact human health and are amplified in more highly exposed communities. Policy regulatory frameworks for making decisions recommendations on interventions to mitigate or prevent exposures tend narrowly focus exposure some health-related data related risks. Typically, such do not consider other factors, essentiality, equity, distribution of benefits costs. Further, lack transparency regarding how they were developed. We...
Preventing adverse health effects of environmental chemical exposure is fundamental to protecting individual and public health. When done efficiently properly, risk assessment enables management actions that minimize the incidence environmentally induced diseases related exposure. However, traditional faced with multiple challenges respect predicting preventing disease in human populations, epidemiological studies increasingly report observations at levels predicted from animal be safe for...