A5042001540- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Pickering emulsions and particle stabilization
- Surfactants and Colloidal Systems
- Aluminum toxicity and tolerance in plants and animals
- Nanoparticles: synthesis and applications
- Ionic liquids properties and applications
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Luminescence Properties of Advanced Materials
- Dendrimers and Hyperbranched Polymers
- Heavy Metal Exposure and Toxicity
- Luminescence and Fluorescent Materials
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Inorganic Fluorides and Related Compounds
- ZnO doping and properties
- Advanced Polymer Synthesis and Characterization
- Polymer Surface Interaction Studies
- Analytical Chemistry and Chromatography
- Supramolecular Self-Assembly in Materials
- DNA and Nucleic Acid Chemistry
- Phagocytosis and Immune Regulation
- Nuclear materials and radiation effects
- Crystallization and Solubility Studies
Institut des Sciences Chimiques de Rennes
2016-2025
Université de Rennes
2014-2024
Centre National de la Recherche Scientifique
2014-2024
Tunis El Manar University
2023
ScanMAT
2022
Université Rennes 2
2020
Institut polytechnique de Grenoble
2018
Université Européenne de Bretagne
2016
Laboratoire de Chimie de Coordination
2001-2016
Softmat - Chimie des colloïdes, polymères & assemblages complexes
2006-2016
The formation of nonionic surfactant micelles in ionic liquids is clearly evidenced for the first time using tensiometry, dynamic light scattering, and small-angle neutron scattering measurements. Changing anion X− a series 1-butyl-3-methyl-imidazolium (with X-=BF4−, PF6−, Tf2N−) allows tuning micelle size aggregation number (see picture; γ=surface tension). Supporting information this article available on WWW under http://www.wiley-vch.de/contents/jc_2267/2006/z500419_s.pdf or from author....
A series of hydrosoluble dendrimers has been synthesized by capping phosphorus-containing with hydrophilic end groups. These form aqueous rigid gels at very low concentration (ca. 1.5 % per weight; see picture), which allows, for example, confinement acids or metals. The structure the investigated freeze-fracture electron microscopy. Supporting information this article is available on WWW under http://www.angewandte.com from author. Please note: publisher not responsible content...
Aluminum has gathered toxicological attention based on relevant human exposure and its suspected hazardous potential. Nanoparticles from food supplements or contact materials may reach the gastrointestinal tract. Here, we monitored physicochemical fate of aluminum-containing nanoparticles aluminum ions when passaging an in vitro model Small-angle X-ray scattering (SAXS), transmission electron microscopy (TEM), ion beam (IBM), secondary mass spectrometry (TOF-SIMS), inductively coupled plasma...
Abstract Reducing the size of upconversion nanoparticles (UCNPs) down to a few nm yields luminescent materials containing very small number emitters. Considering bottom limit one activator per particle ultrasmall UCNPs offer an unprecedented platform study contributions different energy transfers at play in luminescence. Maintaining detectable emission despite limited emitting ions and high surface‐to‐volume ratio requires suitable architectures. Na(Gd‐Yb)F 4 :Tm 3+ emissive sub‐3 diameter...
The application of appropriate analytical techniques is essential for nanomaterial (NM) characterization. In this study, we compared different NM analysis. Regarding possible adverse health effects, ionic and particulate effects have to be taken into account. As NMs behave quite differently in physiological media, special attention was paid which are able determine the biosolubility complexation behavior NMs. Representative similar size were selected: aluminum (Al0) oxide (Al2O3), compare...
We have performed small-angle neutron scattering in a momentum transfer range (0.05 < Q 0.5 Å–1) to study long-range order and concentration fluctuations deep eutectic solvents (DESs) their aqueous solutions. Ethaline (choline chloride/ethylene glycol), glycerol/lactic acid, menthol/decanoic acid mixtures were selected illustrate individually the case of ionic, nonionic, hydrophobic mixtures. Carefully designed isotopic labeling was used emphasize selectively spatial correlations between...
A core−multishell architecture based on a hyperbranched PEI core surrounded by double layered shell of alkyl hydrophobic groups linked to PEO chain was successfully used as stabilizer for the formation and stabilization hydrophilic gold nanoparticles in wide range solvents.
Hybrid gold-polymer nanoparticles are obtained by self-assembly of amphiphilic copolymers (Pluronics) in solutions containing preformed gold (diameter ca. 12 nm). Dynamic light scattering, TEM, cryo-TEM, and small-angle neutron scattering experiments with contrast variation used to characterize the structure particles. Five Pluronics (F127, F68, F88, F108, P84) different molecular weights hydrophilic/hydrophobic balances investigated. Gold individually embedded within globules polymer, even...
Abstract Extracellular vesicles (EVs) are membrane-enclosed nanostructures released by cells into the extracellular environment. As major actors of physiological intercellular communication, they have been shown to be pathogenic mediators several liver diseases. also appear potential drug-induced injury but nothing is known concerning environmental pollutants. We aimed study impact polycyclic aromatic hydrocarbons (PAHs), contaminants, on hepatocyte-derived EV production, with a special...
Aluminum (Al) is one of the most common elements in earth crust and increasingly used food, consumer products packaging. Its hazard potential for humans still not completely understood. Besides metallic form, Al also exists as mineral, including insoluble oxide, soluble ionic forms. Representatives these three species, namely a an oxidic species Al-containing nanoparticles aluminum chloride, were applied to human intestinal cell lines models barrier. We characterized physicochemical particle...
Three chemistry laboratories assess their 2019 carbon footprint. Purchases and energy are key emissions. Mitigation aims for a 40–50% global reduction by 2030, addressing all categories.
We report the first example of a chemical reaction in new type surfactant aggregates called "spherulites" or "onions". Spherulites are spherical microdomains (200−1000 nm) lamellar phase. They prepared by means shear phase under controlled conditions. can be considered as vesicles with dense multilamellar structure. Chemical reduction copper(II) ions encapsulated into spherulites hydrazine demonstrates possibility using this assembly microreactors. describe process encapsulation spherulites....
A new technology is tested for enzyme encapsulation. The capsules are small multilamellar vesicles of surfactant called spherulites which produced by shearing a lamellar phase under well-controlled conditions. Encapsulation alkaline phosphatase into studied here as an example. Once encapsulated, the shown to be unable develop any enzymatic activity on its substrate, p-nitrophenylphosphate. This due absence contact between and substrate. Interestingly, whole recovered after destruction...
In order to achieve a significant size reduction get ultrasmall upconverting nanoparticles (UCNPs) following thermal coprecipitation pathway, we identified two critical points: the UCNP precursor mixing and high-temperature heating steps. Significant differences could be observed according way inorganic sodium fluoride sources were mixed rare-earth oleate before step. More interestingly, accurate monitoring of step using microwave (MW) dielectric yielded major improvement toward UCNPs. Thus,...