A5102895573- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Neonatal Respiratory Health Research
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrest and Resuscitation
- Pharmaceutical Economics and Policy
- Congenital Diaphragmatic Hernia Studies
- Lipoproteins and Cardiovascular Health
- Streptococcal Infections and Treatments
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Injury Epidemiology and Prevention
- Mitochondrial Function and Pathology
- Mechanical Circulatory Support Devices
- Hip disorders and treatments
- Hedgehog Signaling Pathway Studies
- Neurosurgical Procedures and Complications
- Fibroblast Growth Factor Research
- Pharmacological Effects of Natural Compounds
- Intestinal Malrotation and Obstruction Disorders
- Anesthesia and Pain Management
- Pharmacy and Medical Practices
- Superconducting Materials and Applications
- ATP Synthase and ATPases Research
- Soft tissue tumor case studies
Saiseikai Utsunomiya hospital
2013-2025
Hoshigaoka Medical Center
2025
Japan Community Healthcare Organization
2025
Akita University
2021-2025
Pediatrics and Genetics
2011
Nihon University
2001-2009
Surugadai Nihon University Hospital
2008
Kagawa University
2004-2005
Few studies with sufficient statistical power have shown the association of z score coronary arterial internal diameter events (CE) in patients Kawasaki disease (KD) artery aneurysms (CAA).To clarify time-dependent CE occurrence KD CAA.This multicenter, collaborative retrospective cohort study 44 participating institutions included 1006 younger than 19 years who received a angiography between 1992 and 2011.The CE, including thrombosis, stenosis, obstruction, acute ischemic events,...
After focal cerebral ischemia, tumor necrosis factor-alpha deteriorates edema and survival rate. Therefore, neutralization could reduce microvascular permeability in acute ischemia. Left middle artery occlusion for 120 mins followed by reperfusion was performed with the thread method under halothane anesthesia Sprague-Dawley rats. Antirat neutralizing monoclonal antibody a rat IgG Fc portion (15 mg/kg) infused intravenously right after reperfusion. Stroke index score, infarct volume,...
Background Coronary arterial aneurysms (CAAs) associated with Kawasaki disease (KD) significantly affect prognosis. However, the clinical course of CAAs and factors CAA regression have not been well analyzed. Methods Results The cohort Z-Score 2nd Project Stage study, a multicenter, retrospective, study involving 44 institutions in Japan including 1006 patients KD, was examined. were classified by z score their internal diameter acute phase: small (z<5), medium (5≤z<10), large (z≥10). lower...
Background: Circumstances and outcomes of out-of-hospital cardiac arrest (OHCA) in elementary middle school students while at the era public-access defibrillation are unknown. Methods Results: We conducted a nationwide hospital-based survey who had OHCA origin received prehospital resuscitation 2005–2009. Among 58 cases recruited, 90% were witnessed by bystanders; 86% ventricular fibrillation as initial rhythm; 74% resuscitated 24% defibrillated 55% occurred school; 66% exercise-related; 48%...
Abstract Familial adenomatous polyposis (FAP) is an inherited disorder that follows autosomal dominant inheritance pattern and caused by a germline pathogenic variant in the APC gene. FAP also has extracolonic manifestations, including osteomas, brain tumors, congenital hypertrophy of retinal pigmented epithelium. Desmoid tumor rare soft-tissue often associated with FAP. WNT signal transduction molecule abundantly expressed central nervous system. The truncation mutations gene are...
Abstract Background Stroke is a leading cause of death, reducing disability-free life expectancy. After acute treatment, patients require rehabilitation to prevent recurrence. Continued use medication crucial for recurrence prevention and risk management, even after the transition from acute-care institutions other medical institutions. Although “discharge summaries on medications” are shared between hospitals community pharmacists, no reports have addressed continuity with stroke...
Objective Cytochrome c oxidase (COX) deficiency is a major mitochondrial respiratory chain defect that has vast genetic and phenotypic heterogeneity. This study aims to identify novel causative genes of COX with only striated muscle–specific symptoms. Methods Whole exome sequencing was performed in 2 unrelated individuals who were diagnosed congenital myopathy presented muscle pathology. We assessed the COX6A2 variants using measurements enzymatic activities assembly complexes samples from...
The overexpression of imprinted genes on chromosome 6q24 causes 6q24-related transient neonatal diabetes mellitus (6q24-TNDM). Most cases 6q24-TNDM show (DM) during the period, followed by relapse after puberty. These two courses DM are both characterized insulin insufficiency. However, there has been no previously reported case with resistance at relapse. We report a 10-yr-old Japanese girl relapsing 6q24-TNDM. In she had hyperglycemia and was treated injection until 2 mo age. After several...
Flat-sum payment systems for treatment costs, such as the Diagnosis Procedure Combination (DPC) system, are now being introduced in medical institutions. Owing to introduction of systems, hospital pharmacists required be more actively involved selection drugs through provision appropriate drug information including that on cost effectiveness. In Japan, however, very few pharmacoeconomic evaluations by have been reported date. view this, we conducted a evaluation HMG-CoA reductase inhibitors...
It has been demonstrated that HMG-CoA reductase inhibitors effectively decrease low density lipoprotein and total cholesterol levels, presently, are most widely used in hyperlipidemia treatment. On the other hand, it fibrate agents triglyceride levels more compared to inhibitors. A cost-effectiveness study comparing fenofibrate, a agent, atorvastatin was therefore conducted hypertriglyceridemia patients. Referring an analytical method published UK, percentage of patients received fenofibrate...
A novel missense variant