A5048581492- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Congenital Heart Disease Studies
- Atrial Fibrillation Management and Outcomes
- Tracheal and airway disorders
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Congenital Diaphragmatic Hernia Studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Issues in Pregnancy
- Cardiac tumors and thrombi
- Ion channel regulation and function
- Cardiovascular Syncope and Autonomic Disorders
- Vascular anomalies and interventions
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Congenital heart defects research
- Cardiovascular Conditions and Treatments
- Liver Disease and Transplantation
- Congenital Anomalies and Fetal Surgery
- Muscle Physiology and Disorders
- Neurogenetic and Muscular Disorders Research
- Esophageal and GI Pathology
Osaka City General Hospital
2015-2025
Suzuki (Japan)
2021
Kyoto University
2012
Shiga University of Medical Science
2012
Chiba Cerebral and Cardiovascular Center
2012
Xi'an Jiaotong University
2012
Kindai University
2012
Kyushu University
2006
Tokyo Women's Medical University
2006
1 Current status of non‐pharmacotherapies in Japan Pacemaker treatment for bradyarrhythmia was first approved national health insurance coverage Japan 1974, and its use rapidly became widespread thereafter. Approximately 40 years later, 2017, the number patients treated with this technology has increased to 60 137 (41 895 new cases approximately 18 242 replacements). 5 Capsule‐shaped leadless pacemaker also available 2016, is being established as a option. Non‐pharmacological...
The original guideline for non-pharmacological treatments (cardiac implantable electronic device, catheter ablation, and arrhythmia surgery) of arrhythmias (Japanese Circulation Society [JCS] Guideline on Non-pharmacotherapy Cardiac Arrhythmias) was first published in 2001, there have been two revisions thereafter (2006 2011). “JCS Indications Procedures Catheter Ablation” 2012 to cover the rapid development expansion ablation techniques. Advances treatment further accelerated since then,...
Background— Mutations of KCNJ2 , the gene encoding human inward rectifier potassium channel Kir2.1, cause Andersen-Tawil syndrome (ATS), a disease exhibiting ventricular arrhythmia, periodic paralysis, and dysmorphic features. However, some mutation carriers lack ATS triad sometimes share phenotype catecholaminergic polymorphic tachycardia (CPVT). We investigated clinical biophysical characteristics with “atypical ATS.” Methods Results— Mutational analyses were performed in 57 unrelated...
Background: Circumstances and outcomes of out-of-hospital cardiac arrest (OHCA) in elementary middle school students while at the era public-access defibrillation are unknown. Methods Results: We conducted a nationwide hospital-based survey who had OHCA origin received prehospital resuscitation 2005–2009. Among 58 cases recruited, 90% were witnessed by bystanders; 86% ventricular fibrillation as initial rhythm; 74% resuscitated 24% defibrillated 55% occurred school; 66% exercise-related; 48%...
The variant in SCN5A with the loss of function (LOF) effect cardiac Na+ channel (Nav1.5) is definitive cause for Brugada syndrome (BrS), and functional analysis data revealed that LOF variants are associated poor prognosis. However, which types (e.g. missense or non-missense) affect prognoses those carriers remain unelucidated. We defined as all non-missense produce peak INa < 65% wild-type previously confirmed by patch-clamp studies. study population consisted 76 Japanese BrS patients (74%...
In Japan, the use of implantable cardioverter defibrillators (ICDs), cardiac resynchronization therapy with a biventricular pacemaker (CRTP) and CRT defibrillator (CRTD) in children has not been studied statistically, dual-chamber (DDD) pacemakers are still used for pediatric because current government regulations.Data were obtained from 15 children's 74 general hospitals through questionnaire survey regarding aforementioned therapies performed before 2012 Japanese (<16 years old). ICD, DDD,...
Abstract Aim Patients who undergo the Fontan procedure for complex congenital heart disease are prone to liver cirrhosis. Liver stiffness (LS) reflects fibrosis stage in patients with chronic viral hepatitis; however, its accuracy predicting is controversial. We aimed clarify correlation between LS and patients. Methods Fifty‐eight were prospectively measured transient elastography. undertook biopsy, cardiac catheterization, laboratory tests 22 of these (median age, 14.7 years; range,...
Transseptal puncture (TSP) has become a common approach in catheter ablation of arrhythmia originating from the left atrium. In paediatric patients, however, TSP can be challenge due to narrower access vessels and small atrial size, safety smaller children is yet understood. The purpose this study was retrospectively evaluate feasibility weighing below 30 kg.Among 655 patients who underwent between July 2009 April 2015, 43 cases having structurally normal hearts, <30 kg requiring were...
An increasing number of children are undergoing radiofrequency catheter ablation (RFCA) for tachyarrhythmia. However, infants and toddlers RFCA often resistant to medication or need eliminate arrhythmia substrate, the risks complications still high in toddlers. From April 2008 December 2016, 285 who underwent were stratified according body weight (group A, less than 10 kg, n = 22; group B, over 263) clinical features retrospectively reviewed these groups. Indications included drug-refractory...
Wolff-Parkinson-White syndrome is associated with heart failure (HF) mainly via tachycardia. Several case report series have suggested dyssynchrony due to an accessory pathway as a possible cause of HF even in the absence tachyarrhythmias. The role cardiac resynchronization suppression anterograde conduction pathways by catheter ablation or pharmacotherapy such patients remains unclear, especially pediatric population. We describe infant ventricular and refractory tachycardia caused right...
Background We hypothesized that, compared with propofol, desflurane prolongs the antegrade accessory pathway effective refractory period ( APERP ) in children undergoing radiofrequency catheter ablation for Wolff‐Parkinson‐White WPW syndrome. Methods In this randomized crossover study, aged 4.1−16.1 years syndrome were randomly divided into four groups according to concentration of and anesthetics used first second electrophysiological studies EPS ). After induction general anesthesia...
Left ventricular noncompaction (LVNC) is a heterogeneous myocardial disorder characterized by prominent left trabeculae and deep intertrabecular recesses with variable clinical features. The classical triad of complications heart failure, thromboembolic events, arrhythmias including sudden cardiac death. LVNC has been recognized as primary cardiomyopathy genetic origin.1 However, the basis disease in large proportion patients remains unresolved.
Objective Patients who undergo Fontan surgery for complex cardiac anomalies are prone to developing liver and gastrointestinal complications. In particular, gastroesophageal varices (GEVs) can occur, but their prevalence is unknown. We aimed elucidate the occurrence of GEVs predicting parameters in these patients. Materials methods Twenty-seven patients (median age, 14.8 years; median time since surgery, 12.9 years) had undergone were examined by abdominal dynamic computed tomography (CT)...
Criss-cross heart, defined as crossing of the long axis atrioventricular (AV) valves, is an extremely rare congenital heart defect. The unusual arrangement cardiac inlets observed in criss-cross was first described by Lev and Rowlatt1 1961. term "criss-cross heart" initially coined Anderson et al2 1972. reported incidence no greater than 8 per 1,000,000 accounts for <0.1% defects.3 According to relationship AV connection, divided into 2 types: with concordance known concordant whereas...
Key Teaching Points•Ectopic atrial tachycardia originating from aneurysms of the right appendage is very rare among children.•Aneurysms having structural abnormalities such as pectinate muscles and saccular form would prevent catheter insertion radiofrequency ablation.•Surgical treatment often effective for patients with aneurysm multiple tachycardia; however, location or size important surgical treatment.•A combination medications, surgery, ablation should be considered foci aneurysms. •Ectopic
A 39-day-old female infant with Ebstein's anomaly, pulmonary atresia, atrial septal defect, and patent ductus arteriosus developed repetitive critical ventricular tachycardia (VT) ranging from 200 to 240 bpm. We assumed the focal VT originated right ventricle (RV) electrocardiographic features. Pharmacological …