A5100356517- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Dermatologic Treatments and Research
- Infant Nutrition and Health
- Connective Tissue Growth Factor Research
- Digestive system and related health
- Stress Responses and Cortisol
- Wound Healing and Treatments
- Bone and Dental Protein Studies
- Ion Channels and Receptors
- Pain Mechanisms and Treatments
- Contact Dermatitis and Allergies
Guangzhou Medical University
2019-2020
Second Affiliated Hospital of Guangzhou Medical University
2020
State Key Laboratory of Respiratory Disease
2020
East China Normal University
2019
Abstract Background Hypertrophic scars are complications of severe wound healing characterized by excessive fibrosis associated with aberrant function fibroblasts. However, no available drugs can be utilized to effectively treat these scars. The transforming growth factor β ( TGF β) signalling pathway regulates collagen synthesis and plays an important role in scar formation. Objectives To evaluate the anti‐scar effects inhibitors vitro vivo . Methods Col1α2‐luciferase reporter assay was...
Background: Recurrent and intractable chronic itch is a world-wide problem but mechanisms, especially the neural underlying still remain unclear. In this study, we investigated peripheral spinal mechanisms responsible for prolonged in mouse model of allergic contact dermatitis induced by squaric acid dibutylester (SADBE). Methods: Behavioral tests combination to genetic, pharmacological, neurotoxic approaches were performed on models. Immunohistochemistry, RNAscope situ hybridization assay,...