A5035190908- Acute Myeloid Leukemia Research
- Retinoids in leukemia and cellular processes
- Innovations in Medical Education
- Acute Lymphoblastic Leukemia research
- Emergency and Acute Care Studies
- Interprofessional Education and Collaboration
- Immunodeficiency and Autoimmune Disorders
- Gestational Diabetes Research and Management
- Kawasaki Disease and Coronary Complications
- Cardiovascular Issues in Pregnancy
- Pharmacy and Medical Practices
- Empathy and Medical Education
- Hematopoietic Stem Cell Transplantation
- Cleft Lip and Palate Research
- Thermoregulation and physiological responses
- Breastfeeding Practices and Influences
- Folate and B Vitamins Research
- Groundwater and Isotope Geochemistry
- Antioxidant Activity and Oxidative Stress
- Cardiac Arrest and Resuscitation
- Healthcare Education and Workforce Issues
- Trauma and Emergency Care Studies
- Economic and Environmental Valuation
- Infant Development and Preterm Care
- Obesity, Physical Activity, Diet
Showa University
2022-2025
Gifu University
2012-2025
Yokohama City University
2008-2024
Okinawa Prefectural Chubu Hospital
2021
Suzuki (Japan)
2021
Johns Hopkins University
2021
Gifu Women's University
2019
Education Development Center
2017-2018
Osaka Medical and Pharmaceutical University
2003-2014
University of the Ryukyus
2013
This study aimed to examine how students' perceptions of research and learning change through participation in undergraduate identify the factors that affect process their engagement projects.This qualitative has drawn on phenomenography as methodology explore third-year medical experiences from participants' perspectives (n=14). Data included semi-structured individual interviews conducted pre post reflections. Thematic analysis pre-course combined with researcher-participant observations...
Abstract Background Unnecessary ambulance use has become a socioeconomic problem in Japan. We investigated the possible relations between factors and medically unnecessary calls, we estimated incremental demand for produced by factors. Methods conducted self-administered questionnaire-based survey targeting residents of Yokohama, The questionnaire included questions pertaining to characteristics, dichotomous choice method calls hypothetical nonemergency situations, on city's emergency...
Background The aim of this study was to examine how physical activity (PA) before and during pregnancy influences outcomes, particularly preterm delivery mode delivery. Methods This based on the Japan Environment Children's Study. A total 92,796 pregnant women who gave birth live singleton babies were included. Information mean PA per week extracted from responses questionnaires completed by second third trimesters pregnancy. obtained answered recall at participation. level stratified into...
Purpose: Course evaluations are critical for improving educational practices; however, their results can be influenced by various unexpected factors, including cultural values. Despite several studies on dimensions in course evaluations, Japanese students were rarely the focus of evaluation Asian context. Data students' practices may reveal diverse behavioral patterns countries, highlighting value country-specific to uncover unique contexts. This study explores, through a lens, how medical...
OBJECTIVES To identify community preceptors’ views on the qualities and abilities required of physicians in medicine, education to acquire those abilities, factors affecting involvement community-based teaching. METHODS We conducted semi-structured interviews with 13 male preceptors northern Japan who had at least 5 years experience medicine prior teaching preclinical students. Participants were selected using purposive sampling ensure diversity clinical roles institutional affiliations. A...
Steroid-induced osteonecrosis (ON) is a challenging complication encountered during modern chemotherapy for childhood acute lymphoblastic leukemia (ALL). We retrospectively assessed the incidence of ON and its risk factors in total 1095 patients enrolled 3 consecutive Japanese Children's Cancer Leukemia Study Group ALL studies (ALL941 [1994 to 2000], n=464; ALL2000 [2000 2004], n=305; ALL2004 [2004 2010], n=326). was diagnosed 16 patients, whom 15 were symptomatic. The cumulative 0.76%...
Clinical decision-making skills are essential for providing high-quality patient care. To enhance these skills, many institutions worldwide use case-based learning (CBL) as an educational strategy of pre-clinical training. However, to date, the influence different modalities on students' clinical processes has not been fully explored. This study aims explore video and paper case process midwifery students during CBL.CBL involving a normal pregnant woman was provided 45 students. They were...
Summary Background Previous studies have demonstrated an inverse relationship between socioeconomic status and childhood obesity in affluent nations, with parental education as a key factor. However, the meaning of indicators may vary by race country, research on this topic Asian countries is limited. Objectives We investigated association parents' educational Japan. Methods utilized data from Japan's birth cohort, recruiting participants 2011 to 2014, included 49 564 children. Parental was...
Aim: Ezetimibe selectively blocks intestinal cholesterol absorption by inhibiting Niemann-Pick C1-like 1 (NPC1L1) and reducing LDL (LDL-C). In animals, ezetimibe reversed diet-induced obesity, liver steatosis, insulin resistance. humans, its potential effects on steatosis resistance have been suggested. We investigated the of postprandial hyperlipidaemia hyperglycaemia in obese subjects with dyslipidaemia a double-blind randomized crossover trial.Methods: Twenty men hypertriglyceridaemia...
Background Cleft lip and palate (cleft L/P) is one of the most common congenital anomalies its etiology assumed to be multifactorial. Recent epidemiological data involving a small number participants suggested an association between perinatal exposure heavy metals cleft L/P in affected children. However, this requires further investigation large cohort. Methods This nested case–control study used dataset The Japan Environment Children’s Study, which ongoing research project investigate...
Tocotrienols (Toc3) have been suggested to possess anticancer effects besides antioxidant and antiinflammatory effects. Previous studies demonstrated that Toc3 induce apoptosis in epithelial carcinoma. However, the of on malignant hematopoietic cells not yet thoroughly investigated. We investigated Toc3-induced human hematological cancer cell lines. α-, δ-, γ-Toc3 induced concentration-dependent apoptosis, more effective induction than other derivatives HL-60 cells. may by activation caspase...
Orofacial clefts are common birth defects with a lack of strong evidence regarding their association maternal nutrition. We aimed to determine whether relationship exists between nutrient or multivitamin intake and orofacial clefts.This is prospective, population-based nationwide cohort study.The study was conducted in 15 regional centres, consisting local administrative units areas.A total 98 787 eligible mother-child pairs the Japan Environment Children's Study were included.Exposures...
<b><i>Introduction:</i></b> Food protein-induced enterocolitis syndrome (FPIES) is a form of non-IgE-mediated gastrointestinal food allergy. FPIES considered rare allergy disorder and often under-recognized. Therefore, clinicians should have better understanding its manifestations maintain high index suspicion for correct diagnosis. To this end, information about differences in the characteristics caregiver-reported physician-diagnosed important....
Kawasaki disease (KD) is an acute systemic vasculitis primarily affecting young children, with unclear etiology. We investigated the link between maternal heavy metal exposure and KD incidence in children using Japan Environment Children's Study, a large-scale nationwide prospective cohort approximately 100,000 mother-child pairs. Maternal blood samples collected during second/third trimester were analyzed for metals [mercury (Hg), cadmium (Cd), lead (Pb), selenium (Se), manganese (Mn)],...
Abstract Background Although childhood undervaccination among single mother families is a concern for child healthcare, their association still under debate. This study aimed to investigate the between maternal marital status and risk of determine mediating effect household income. Methods We utilised prospective birth cohort from Japan Environment Children’s Study (JECS). Of 104,062 foetal records (children) 97,413 mothers, 82,462 that included mothers recruited 2011 2014, were analysed....
How medical residents' experiences with care for dying patients affect their emotional well-being, learning outcomes, and the formation of professional identities is not fully understood. We examine states occurring during provision to specifically discuss impact providing end-of-life (EOL) on identity formation. Semi-structured interviews were conducted 13 residents who had graduated in last 3 5 years. Thematic theoretical analysis was applied, key themes developed based Kolb's experiential...
We herein present a case of pediatric therapy-related myelodysplastic syndrome (t-MDS) with complex karyotype who was treated azacitidine (AZA) for AML1-EVI1 fusion transcript as minimal residual disease after allogeneic hematopoietic stem cell transplantation (HSCT). The patient started on AZA 41 days the HSCT without having achieved complete remission. After 9 cycles AZA, disappeared, and there no manifestation graft versus host during treatment. Preemptive treatment has an acceptable...
In Japan, anyone can use an ambulance free of charge, but this policy may encourage unnecessary use.To determine the user price that would reduce use, without discouraging medically necessary use.The study was conducted by means a three-part self-administered questionnaire. The first part consisted questions covering demographic variables such as respondent age, gender, family structure, and pretax annual household income. second made up contingent valuation on use. Respondents were...
Abstract Kawasaki disease (KD) is an acute systemic vasculitis that mainly affects infants and young children. The etiology of KD has been discussed for several decades; however, no reproducible risk factors have yet proven. We used the Japan Environment Children’s Study data to explore association between causal effects exposure during fetal neonatal periods onset. Study, a nationwide birth cohort study, followed approximately 100,000 children since 2011. obtained on exposures outcomes from...