A5091226254- Catalysis and Oxidation Reactions
- Catalytic Processes in Materials Science
- Oxidative Organic Chemistry Reactions
- Birth, Development, and Health
- Asthma and respiratory diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Mesoporous Materials and Catalysis
- Metallic Glasses and Amorphous Alloys
- Venous Thromboembolism Diagnosis and Management
- Obesity, Physical Activity, Diet
- Pharmaceutical Practices and Patient Outcomes
- Palliative Care and End-of-Life Issues
- Smoking Behavior and Cessation
- Neonatal Respiratory Health Research
- Radioactive element chemistry and processing
- Epilepsy research and treatment
- Folate and B Vitamins Research
- Gestational Diabetes Research and Management
- Pregnancy and Medication Impact
- Antiplatelet Therapy and Cardiovascular Diseases
- Polyoxometalates: Synthesis and Applications
- Cleft Lip and Palate Research
- Pharmacovigilance and Adverse Drug Reactions
- Transition Metal Oxide Nanomaterials
- Child Nutrition and Feeding Issues
Kyoto University
2009-2025
University of Tsukuba
2024-2025
Osaka International Cancer Institute
2024
Ohu University
2018-2020
Public Health Department
2018
University Hospital Kyoto Prefectural University of Medicine
2005
Children's Research Hospital
2005
Kobe University Hospital
1996
Abstract Background Although associations between antibiotic exposure in infants and asthma development are reported, few studies have examined the effects of prenatal to antibiotics. We evaluated this association considering types using a large‐scale claim database Japan. Methods This retrospective study health insurance administrative data Japan included children born January 2005 September 2014. constructed 2 cohorts: initial cohort, with information on children's mothers, sibling at...
Antibiotics are the most frequently prescribed medications for children but inappropriate antibiotic prescribing is prevalent. The purpose of our study was to access nationwide trend in prescriptions, and ascertain upper respiratory infections (URIs) pre-school Japan. Data from administrative claims database 2005 January 2014 September Japan were examined. We identified outpatient prescription described patterns subjects who followed birth 6 years age. Logistic regression analyses performed...
Nephrotic syndrome is associated with an increased risk of venous thromboembolism (VTE). However, the factors VTE in nephrotic syndrome, other than hypoalbuminemia and severe proteinuria, are not well established. Therefore we aimed to investigate patients syndrome.
ABSTRACT Objectives The diagnosis of early‐onset Alzheimer's disease (EOAD) can cause emotional stress not only to the patients themselves but also their spouses. This study aimed evaluate risk psychiatric disorders in spouses EOAD patients, using psychotropic drug initiation as a surrogate indicator. Methods A cohort was conducted Japanese claims database, with (exposed spouses) matched non‐EOAD individuals (reference up 1:10 ratio. Primary outcome mood disorder drugs, and secondary...
To elucidate the incidence and treatment pattern of active exudative age-related macular degeneration (AMD).A population-based cohort study conducted using National Database Health Insurance Claims Specific Checkups Japan (NDB), a national claims database managed by Japanese Ministry Health, Labour, Welfare (MHLW).The entire population aged 40 years or older (76 million people).With permission MHLW, we accessed complete NDB dataset identified patients with newly diagnosed AMD between 2011...
Summary Background Previous studies have demonstrated an inverse relationship between socioeconomic status and childhood obesity in affluent nations, with parental education as a key factor. However, the meaning of indicators may vary by race country, research on this topic Asian countries is limited. Objectives We investigated association parents' educational Japan. Methods utilized data from Japan's birth cohort, recruiting participants 2011 to 2014, included 49 564 children. Parental was...
Background Cleft lip and palate (cleft L/P) is one of the most common congenital anomalies its etiology assumed to be multifactorial. Recent epidemiological data involving a small number participants suggested an association between perinatal exposure heavy metals cleft L/P in affected children. However, this requires further investigation large cohort. Methods This nested case–control study used dataset The Japan Environment Children’s Study, which ongoing research project investigate...
Objective . To assess dose, characteristics, and coprescribed analgesics in patients newly prescribed pregabalin for neuropathic pain fibromyalgia Japan. Methods Based on the medical prescription information present Medical Data Vision database, we analyzed initial maximum daily doses, period, analgesics, pain-related disorders of between 01 July 2010 31 December 2013. Results A total 45,331 (mean age 66.8 years, 48.7% men) were during this period. The mean doses 97.3 mg 127.8 mg,...
Orofacial clefts are common birth defects with a lack of strong evidence regarding their association maternal nutrition. We aimed to determine whether relationship exists between nutrient or multivitamin intake and orofacial clefts.This is prospective, population-based nationwide cohort study.The study was conducted in 15 regional centres, consisting local administrative units areas.A total 98 787 eligible mother-child pairs the Japan Environment Children's Study were included.Exposures...
Pt I~u and Ln-edges XANES clarified the oxidation state of platinum catalysts supported on various metal oxides.The acidbase property seemed one most dominant factors to control electron platinum.On reduced samples, there was a tendency that acidic support 5d-electron density platinum, while oxidized samples contained more metallic platinum.The latter agreed well with high activity supports toward propane combustion in oxidizing condition, it explained by hypothetical mechanism for...
Studies using data from Western countries have raised concerns that treating pregnant women with antidepressants may increase the risk of autism spectrum disorders (ASDs) in their offspring. However, to date, studies are inconclusive. We therefore examined association between antidepressant use and ASD claims collected Japan.This retrospective cohort study was based on mothers children January 2005 July 2014, obtained Japan Medical Data Center. The information linked family identification...
Certain studies previously pointed out that treating pregnant women with antidepressants may increase risks of congenital anomalies in their children. However, to date, the study results are not conclusive. Furthermore, most have been performed using data from Western countries; therefore, we examined this association Japanese data. This retrospective cohort was based on claims mothers and children January 2005 July 2014, obtained JMDC Inc. Information antidepressant prescriptions extracted...
A safety signal concerning parkinsonism and related movement disorders with gabapentinoids (gabapentin pregabalin) or tramadol was detected by reviewing individual case reports data mining in spontaneous report databases. Well-designed pharmacoepidemiological studies are needed to assess the signal.This study aimed investigate association of exposure risk disorders.We conducted a case-crossover using Japanese electronic medical records database. Patients newly diagnosed between January 1,...
Abstract This study aimed to assess the effects of thienopyridine-class antiplatelet agents (including ticlopidine, clopidogrel, and prasugrel) on bleeding complications in patients who underwent robot-assisted radical prostatectomy. cohort used a database for prostatectomy at 23 tertiary centers nationwide between 2011 2022. Patients received thienopyridines (thienopyridine group) were compared with those aspirin monotherapy (aspirin group). The primary outcome was incidence complications....
Kawasaki disease (KD) is an acute systemic vasculitis primarily affecting young children, with unclear etiology. We investigated the link between maternal heavy metal exposure and KD incidence in children using Japan Environment Children's Study, a large-scale nationwide prospective cohort approximately 100,000 mother-child pairs. Maternal blood samples collected during second/third trimester were analyzed for metals [mercury (Hg), cadmium (Cd), lead (Pb), selenium (Se), manganese (Mn)],...