A5011231362- Data-Driven Disease Surveillance
- Food Safety and Hygiene
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- HIV/AIDS Research and Interventions
- Animal Disease Management and Epidemiology
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- HIV, Drug Use, Sexual Risk
- Influenza Virus Research Studies
- Food Supply Chain Traceability
- Vaccine Coverage and Hesitancy
- Travel-related health issues
- Pharmacovigilance and Adverse Drug Reactions
- Pneumonia and Respiratory Infections
- Smoking Behavior and Cessation
- Virology and Viral Diseases
- Health Literacy and Information Accessibility
- Disaster Management and Resilience
- COVID-19 Clinical Research Studies
- Statistical Methods in Clinical Trials
- Machine Learning in Healthcare
- Vector-borne infectious diseases
- Patient Satisfaction in Healthcare
- Medical Coding and Health Information
Harvard University
2014-2025
Harvard Pilgrim Health Care
2021-2025
Pfizer (United States)
2023
Brigham and Women's Hospital
2023
Johns Hopkins Medicine
2023
Johns Hopkins University
2023
Boston University
2015-2018
Boston Children's Hospital
2014-2017
Boston Children's Museum
2016
Massachusetts Institute of Technology
2014-2015
Traditional surveillance systems capture only a fraction of the estimated 48 million yearly cases foodborne illness in United States. We assessed whether foodservice reviews on Yelp.com (a business review site) can be used to support efforts.We obtained from 2005 2012 5824 businesses closest 29 colleges. After extracting recent describing episodes illness, we compared implicated foods outbreak reports U.S. Centers for Disease Control and Prevention (CDC).Broadly, distribution across five...
Abstract As of July 15, 2015, the South Korean Ministry Health and Welfare had reported 186 case-patients with Middle East respiratory syndrome in Korea. For 159 known outcomes complete case histories, we found that older age preexisting concurrent health conditions were risk factors for death.
Abstract Purpose Health plan claims may provide complete longitudinal data for timely, real‐world population‐level COVID‐19 assessment. However, these often lack laboratory results, the standard diagnosis. Methods We assessed validity of ICD‐10‐CM diagnosis codes identifying patients hospitalized with in U.S. databases, compared to linked among six Food and Drug Administration Sentinel System partners (two large national insurers, four integrated delivery systems) from February 20–October...
The speed with which disease outbreaks are recognized is critical for establishing effective control efforts. We evaluate global improvements in the timeliness of outbreak discovery and communication during 2010-2014 as a follow-up to 2010 report. For all reported by World Health Organization's Disease Outbreak News, we estimate number days from first symptoms until public communication. report median delays overall, region, Human Development Index (HDI) quartile. use Cox proportional...
Lyme disease (LD) is the most common vector-borne in United States, though traditional LD surveillance underestimates burden of disease. We validated algorithms for early localized and disseminated LD, with without LD-specific diagnosis codes, states high incidence their neighboring low incidence. identified cohorts potential incident cases administrative insurance claims data, October 2015-October 2023, 1 national regional insurer. Three were studied: a primary algorithm an code indicated...
In this commentary, we consider the relationship between early outbreak changes in observed reproductive number of Ebola West Africa and various media reported interventions aggravating events. We find that reports provided education, minimized contact, or strengthened healthcare were typically followed by sustained transmission reductions both Sierra Leone Liberia. Meanwhile, events generally preceded temporary increases countries. Given these preliminary findings, conclude could...
Compared with notifiable disease surveillance, claims-based algorithms estimate higher Lyme incidence, but their accuracy is unknown. We applied a previously developed algorithm (diagnosis code plus antimicrobial drug prescription dispensing within 30 days) to an administrative claims database in Massachusetts, USA, identify cohort during July 2000-June 2019. Clinicians reviewed and adjudicated medical charts from subset by using national surveillance case definitions. calculated positive...
Although digital reports of disease are currently used by public health officials for surveillance and decision making, little is known about environmental factors compositional characteristics that may influence reporting patterns. The objective this study to quantify the association between climate, demographic socio-economic on at US county level. We reference approximately 1.5 million foodservice business reviews 2004 2014, use census data, machine learning methods regression models...
Long-term antiretroviral therapy (ART) adherence is critical for achieving optimal HIV treatment outcomes. Fixed-dose combination (FDC) single-pill regimens, introduced in South Africa April 2013, has simplified pill taking. We evaluated outcomes among patients initiated on a FDC compared to similar multi-pill ART regimen Johannesburg, Africa.We conducted retrospective cohort study of ART-naïve HIV-positive non-pregnant adult (≥18 years) without tuberculosis who first-line tenofovir and...
Abstract Objective The 2015 WHO recommendation to initiate all HIV patients on antiretroviral therapy ( ART ) at diagnosis could potentially overextend health systems and crowd out sicker patients, mitigating the policy's impact. We evaluate whether South Africa's prior eligibility expansion from CD 4 ≤ 200 350 cells/μl reduced uptake in sickest patients. Methods Using data presenting Hlabisa Treatment Care Programme KwaZulu‐Natal April 2010 June 2012 n = 13 809), we assessed impact of...
The goal of the HealthMap Vaccine Finder is to provide a free, comprehensive, online service where users can search for locations that offer immunizations. In this article, we describe data and systems underlying (HVF) summarize project's first year operations.We collected on vaccination services from variety providers 2012-2013. Data are used populate an online, public, searchable map.In its year, HVF information 1256 representing 46 381 locations. public Web site received 625 124 visits...
Foodborne illness affects 1 in 4 Americans, annually. However, only a fraction of affected individuals seek medical attention. In this presentation, we will discuss our collaboration with local public health departments to develop foodborne disease surveillance platform supplement ongoing efforts. The currently uses digital data from Twitter and Yelp. We developed machine learning classifier differentiate between relevant irrelevant data. had an accuracy precision 85% 82%, respectively based...
Simplified drug regimens may improve retention in care for persons with chronic diseases. In April 2013, South Africa adopted a once-daily single-pill human immunodeficiency virus (HIV) treatment regimen as the standard of care, replacing multiple-pill regimen. Because had similar biological efficacy, shift to therapy offered real-world test impact simplified drug-delivery mechanisms on patient behavior. Using quasi-experimental regression discontinuity design, we assessed among patients...
Purpose: Foodborne illness is an underreported global public health problem. In collaboration with departments in the United States, we developed a platform to enable local surveillance of foodborne reported on social media and restaurant review sites for supplementing traditional disease programs. this talk, will present discuss potential impact factors such as weather socio-economic disparities. Methods & Materials: Our database consists 1.5 million foodservice reviews approximately 742...
To assess whether recombinant zoster vaccine (RZV) is associated with an increased risk of new-onset gout among US adults aged ≥50 years.
In this study, we assessed reports of foodborne illness in foodservice reviews as a possible data source for disease surveillance. We observed that on Yelp were sometimes extremely detailed. also located clusters particular restaurants, some which had health safety violations related to food handling and hygiene. Most importantly, found foods implicated correlated with outbreak from the CDC. This could be useful identifying vehicles attribution estimation extent illness.
Objectives: The purpose of the study was to examine whether Healthcare Common Procedure Coding System (HCPCS) billing codes should be used in conjunction with National Drug Codes (NDCs) establish insulin exposure episodes. Materials and Methods: We identified claims billed by NDCs or HCPCS FDA’s Sentinel from 2013 2018. created episodes separately based on only, a combination both NDC HCPCS. considered gaps <30 days between valid as continuous exposure. Patients were followed until...
Abstract Background Lyme disease (LD) is the fifth most reported notifiable in US, but true burden remains unknown due to inconsistent reporting. Claims-based algorithms estimate a ≥10-fold higher incidence compared notifiable-disease surveillance, these are unvalidated. Methods We evaluated claims-based LD algorithm based on ICD codes (ICD-9-CM 088.81 or ICD-10-CM A69.2X) and ≥7-day course of an antibiotic used treat dispensed ±30 days diagnosis. applied Harvard Pilgrim Health Care (HPHC)...