A5019324824- Neurological disorders and treatments
- Heavy Metal Exposure and Toxicity
- Parkinson's Disease Mechanisms and Treatments
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Employment and Welfare Studies
- Genetic Neurodegenerative Diseases
- Retirement, Disability, and Employment
- Workplace Health and Well-being
- Neuroscience and Neural Engineering
- Child Nutrition and Water Access
- Boron Compounds in Chemistry
- Botulinum Toxin and Related Neurological Disorders
- Dental Radiography and Imaging
- Dementia and Cognitive Impairment Research
- Neurological and metabolic disorders
- Aluminum toxicity and tolerance in plants and animals
- Peripheral Artery Disease Management
- Trace Elements in Health
- Anesthesia and Neurotoxicity Research
- Forensic Anthropology and Bioarchaeology Studies
- Glycogen Storage Diseases and Myoclonus
- Muscle Physiology and Disorders
- Medical and Biological Ozone Research
- Epilepsy research and treatment
University of Michigan
2020-2024
Harvard University
2024
Yale University
2018-2020
University of Nebraska at Omaha
2016
<b><i>Background:</i></b> The burden of mild (i.e., subclinical) tremor within essential (ET) families is not fully understood. We assessed the in a cohort 287 adults, none whom reported or were diagnosed with ET. <b><i>Methods:</i></b> recruited adults 2 groups based on familial risk for ET: 244 high-risk individuals reporting one more first-degree relative ET) and 43 low-risk no relatives ET). Tremor was objectively 4 hand-drawn spirals...
Introduction: Essential tremor (ET) is a common neurological disorder associated with functional impairment. Emerging evidence shows that some ET caregivers experience burden, but the unique interpersonal aspects of caregiving in context have not been fully examined. Research design: Open-ended questions were administered to 98 care-recipient–caregiver dyads. Responses analyzed using conventional content analysis. Results: The visibility disability and feelings embarrassment occur prompts be...
This study assessed whether self-rated physical and mental work demands were associated with cognition among older working adults their effects dependent.
Background: Essential tremor (ET) cases often exhibit a range of mild cerebellar signs. Their unaffected relatives have been shown in prior studies to subtle (i.e., pre-clinical) disease features. Objective: To quantify signs first-degree ET stratified based on their severity. Methods: 269 cases, none whom reported or diagnosis ET, were diagnosed with detailed neurological examination, total score (TTS) into two groups (lower TTS vs. higher TTS) and quartiles. Changes gait, balance intention...
Despite a growing body of knowledge regarding essential tremor (ET), past studies have fallen short in capturing the full impact ET on patients and caregivers. We propose enfeeblement (i.e., having qualities being prematurely old, helpless, or debilitated) as novel clinical outcome measure ET. Due to lack scales for literature, we developed validated an scale ET.The Essential Tremor Enfeeblement Survey (ETES) consists eight 5-point Likert-type questions is designed be caregiver-reported...
Individuals with essential tremor (ET), a common movement disorder, experience functional impairment, which contributes to burden experienced by their loved ones and caregivers. Some burdened caregivers report as seeming debilitated or prematurely old, concept that we have called enfeeblement. Using the Essential Tremor Enfeeblement Survey (ETES), seek characterize enfeeblement in elders ET assess its contribution caregiver burden.We administered ETES (range = 8-40, higher scores indicating...
<strong>Background:</strong> Individuals with essential tremor (ET), a common movement disorder, experience functional impairment, which contributes to burden experienced by their loved ones and caregivers. Some burdened caregivers report as seeming debilitated or prematurely old, concept that we have called <em>enfeeblement</em>. Using the Essential Tremor Enfeeblement Survey (ETES), seek characterize enfeeblement in elders ET assess its contribution caregiver burden....
Introduction: Patients with peripheral artery disease (PAD) develop myofiber degeneration and fibrosis in their ischemic lower extremities, along limb dysfunction. Walking performance improves revascularization exercise therapy, but effects on the myopathy are unknown. We previously showed progresses PAD positively correlates expression of vascular transforming growth factor-beta 1 (TGF-β1), a cytokine that stimulates collagen deposition. Hypothesis: hypothesize (RVS) supervised therapy...
Abstract Background The number of older adults remaining in the workforce is growing, but little known about how physical and mental work demands jointly affect cognitive health. This study assessed whether self‐rated were associated with cognition among working their associations dependent. Methods Our cross‐sectional sample consisted 6,376 2004 wave Health Retirement Study. Self‐rated summarized from four questions frequency or respondent’s current job. Cognition was using a subset...