Abstract Objectives: Patients with essential tremor exhibit heterogeneous cognitive functioning. Although the majority of patients fall under broad classification cognitively “normal,” is associated increased risk for mild impairment and dementia. It possible that patterns performance within wide range normal functioning have predictive utility or These cross-sectional analyses sought to determine whether patterns, “clusters,” could be identified among individuals diagnosed as normal. We...

Abstract Objectives: Essential tremor (ET) confers an increased risk for developing both amnestic and non-amnestic mild cognitive impairment (MCI). Yet, the optimal measures detecting changes in individuals with this movement disorder have not been established. We sought to identify domains specific motor-free neuropsychological tests that are most sensitive deficits cognition as defined by a Clinical Dementia Rating (CDR) of 0.5, which is generally associated clinical diagnosis MCI....

Background: Essential tremor (ET) encompasses a variety of features, including tremor, cognitive dysfunction, and gait balance impairments. Gait impairments in ET are often mild, but they can be severe are, some cases, associated with functional sequelae terms increased fall risk reduced confidence. Previous research on has been limited to cross-sectional comparisons. There have no longitudinal studies or prospective studies. As such, our understanding natural history possible predictors...

Objective: Essential tremor (ET) is among the most common neurologic diseases. Although in past it was considered a benign condition, recent research has demonstrated increased risk of mortality. To date, however, no studies have examined predictors mortality ET. Methods: In longitudinal, prospective study 141 elders with ET, we used Cox proportional-hazards models to estimate hazard ratios (HRs) for death. Results: The mean baseline age 81.1 ± 8.8 years. During follow-up interval, 27...

Dementia is a devastating neurological disease that may be better managed if diagnosed earlier when subclinical neurodegenerative changes are already present, including subtle cognitive decline and mild impairment. In this study, we used item-level performance on the Montreal Cognitive Assessment (MoCA) to identify individuals with decline.

Objective. Essential tremor (ET) is associated with psychological difficulties, including anxiety and depression. Demoralization (feelings of helplessness, hopelessness, inability to cope), another manifestation distress, has yet be investigated in ET. Our objectives are (1) estimate the prevalence demoralization ET, (2) assess its clinical correlates, (3) determine whether correlates severity. Methods. We administered Kissane Scale (KDS-II) several psychosocial evaluations (ie, scales...

BACKGROUNDDispositional optimism, the expectation of positive outcomes after personal challenges, is a resilience factor associated with widespread health benefits. However, data on pregnancy-related are more limited.OBJECTIVEThis study aimed to assess association early pregnancy dispositional optimism adverse perinatal outcomes.STUDY DESIGNThis was prospective cohort completed between May 2019 and February 2022 at single, large tertiary medical center. Nulliparous pregnant people were...

( Am J Obstet Gynecol . 2023;229:327:e1–16) A tool that could help identify women at risk for stillbirth would be a welcome addition to clinical practice. Machine learning models, which can look relationships between variables in large data sets, was investigated this article. This study’s aim refine machine model predict using available prior the gestational age of viability (22 24 wk). The researchers performed secondary analysis Stillbirth Collaborative Research Network (SCRN), study...

Objective Adverse pregnancy outcomes, including preterm birth and preeclampsia, are associated with worse cardiovascular outcomes for offspring. Examination of the placenta is important understanding how prenatal period shapes long-term health. We sought to investigate association between placental vascular malperfusion fetal cardiac structure. Study Design Data obtained from Stillbirth Collaborative Research Network included stillbirths pathology autopsy. Stillbirths were classified in two...

Objective Dispositional optimism (DO) is an understudied transdiagnostic resilience factor among peripartum individuals. Low DO associated with increased fear and pain in labor rates of emergent cesarean delivery, but it unknown whether perceived control over the process. Study Design This a planned secondary analysis prospective observational cohort term parturients (n = 164) who were recruited July August 2021 during their delivery hospitalization at single, tertiary medical center....

Introduction: Essential tremor (ET) is a common neurological disorder associated with functional impairment. Emerging evidence shows that some ET caregivers experience burden, but the unique interpersonal aspects of caregiving in context have not been fully examined. Research design: Open-ended questions were administered to 98 care-recipient–caregiver dyads. Responses analyzed using conventional content analysis. Results: The visibility disability and feelings embarrassment occur prompts be...

Subtle cognitive decline represents a stage of deterioration in which pathological biomarkers may be present, including early cortical atrophy and amyloid deposition. Using individual items from the Montreal Cognitive Assessment k-modes cluster analysis, we previously identified three clusters individuals without overt impairment: (1) High Performing (no deficits performance), (2) Memory Deficits (lower memory (3) Compound executive function performance). In this study, sought to understand...

Resilience is associated with mental and somatic health benefits. Given the social, physical, toll of coronavirus disease 2019 (COVID-19) pandemic, we examined whether COVID-19 pandemic was population-level changes in resilience among pregnant people. Secondary analysis a prospective cohort nulliparous people <20 weeks' gestation from single hospital. Participants completed baseline assessments characteristics, including dispositional optimism (DO), mindfulness, proactive coping. For this...

Objective: Outside of pregnancy, proactive coping has been associated with both mental and physical well-being improved quality life in chronic disease, but its effects pregnancy are understudied. Our objective was to evaluate whether early adverse perinatal outcomes. Study Design: This a planned secondary analysis nulliparous pregnant people recruited from tertiary care center. Participants completed validated assessment ( Proactive Coping Scale ) at 8– 20 weeks were followed longitudinally...

Background Uterine leiomyomata have been loosely associated with intrauterine fetal demise (IUFD), largely attributed to growth restriction from cavitary distortion. We present two cases of IUFD in patients non-distorting and pathologic placental findings maternal vascular malperfusion (MVM) (FVM).Case Report Case 1 details a 28w3d large (largest 11.9 × 7.6 9.7 cm), post-partum deep vein thrombosis, severe pre-eclampsia histologic features. 2 25w2d smaller 3.1 3.0 3.3 cm). Both placentas...

a The pertinent yes or no question on the survey was, "Please let me know if you found father of baby helpful supportive [time point]."This was asked 3 times to reference different time points: before stillbirth, immediately after diagnosis and 2 months following stillbirth.b Nonadjusted odds ratio from univariate logistic regression.c Adjusted for maternal race ethnicity, prepregnancy depression anxiety, substance use during pregnancy in multivariate regression.Prepregnancy anxiety were...