A5015534543- Gestational Diabetes Research and Management
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Birth, Development, and Health
- Preterm Birth and Chorioamnionitis
- Neonatal Respiratory Health Research
- Maternal Mental Health During Pregnancy and Postpartum
- Bariatric Surgery and Outcomes
- Global Maternal and Child Health
- Prenatal Screening and Diagnostics
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pregnancy and Medication Impact
- Diabetes Management and Research
- Breastfeeding Practices and Influences
- COVID-19 Impact on Reproduction
- Cardiovascular Issues in Pregnancy
- Healthcare Policy and Management
- Reproductive Health and Contraception
- Air Quality and Health Impacts
- Congenital Anomalies and Fetal Surgery
- Grief, Bereavement, and Mental Health
- Prenatal Substance Exposure Effects
Tufts Medical Center
2021-2025
Tufts University
2021-2025
Health and Human Development (2HD) Research Network
2023-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2010-2025
Brown University
2014-2023
Women & Infants Hospital of Rhode Island
2014-2023
Providence College
2013-2022
Rhode Island Department of Health
2022
Island Institute
2011-2021
Society for Maternal-Fetal Medicine
2012-2021
The International Association of the Diabetes and Pregnancy Study Groups (IADPSG) recently recommended new criteria for diagnosing gestational diabetes mellitus (GDM). This study was undertaken to determine whether adopting IADPSG would be cost-effective, compared with current standard care.
To determine whether routine measurement of second-trimester transvaginal cervical length by ultrasound in low-risk singleton pregnancies is a cost-effective strategy.We developed decision analysis model to compare the cost-effectiveness two strategies for identifying at risk preterm birth: (1) no screening and (2) single 18-24 weeks' gestation. In our model, women identified as being increased (cervical < 1.5 cm) birth would be offered daily vaginal progesterone supplementation. We assumed...
In Brief OBJECTIVE: To compare neonatal outcomes by method of delivery in preterm (34 weeks gestation or prior), small-for-gestational-age (SGA) newborns a large diverse cohort. METHODS: Birth data for 1995–2003 from New York City were linked to hospital discharge data. Data limited singleton, liveborn, vertex neonates delivered between 25 and 34 gestation. Births complicated known congenital anomalies birth weight less than 500 g excluded. Small gestational age was used as surrogate...
Exposure to phthalates, a class of endocrine disrupting chemicals, is ubiquitous. We examined the association urinary phthalate metabolite concentrations during pregnancy with maternal blood pressure and risk pregnancy-induced hypertensive diseases. used data from Health Outcomes Measures Environment Study, prospective birth cohort low-risk pregnant women recruited between March 2003 January 2006. analyzed urine samples collected at 16 26 weeks gestation for 9 monoester metabolites...
In Brief OBJECTIVE: To develop a decision model to evaluate the risks, benefits, and costs of different approaches aspirin prophylaxis for approximately 4 million pregnant women in United States annually. METHODS: We created four States: no prophylaxis, per American College Obstetricians Gynecologists (the College) recommendations, U.S. Preventive Services Task Force universal prophylaxis. included associated with aspirin, preeclampsia, preterm birth, potential aspirin-associated adverse...
Importance A short cervix as assessed by transvaginal ultrasound is an established risk factor for preterm birth. Study findings a cervical pessary to prevent delivery in singleton pregnancies with evidence of have been conflicting. Objective To determine if placement decreases the birth or fetal death prior 37 weeks among individuals cervix. Design, Setting, and Participants We performed multicenter, randomized, unmasked trial comparing vs usual care from February 2017 through November 5,...
To examine the effect of underlying maternal morbidities on odds death during delivery hospitalization.We used data that linked birth certificates to hospital discharge diagnoses from singleton live births at 22 weeks gestation or later 1995-2003 in New York City. Maternal examined included prepregnancy weight more than 114 kilograms (250 pounds), chronic hypertension, pregestational gestational diabetes mellitus, cardiovascular disease, pulmonary lung human immunodeficiency virus (HIV), and...
Traffic-related air and noise pollution may increase the risk for cardiovascular disorders, especially among susceptible populations like pregnant women. The objective of this study was to evaluate association exposure traffic-related traffic with blood pressure in We extracted systolic (SBP) diastolic (DBP) at ≥20 weeks gestation, as well hypertensive disorders pregnancy from medical records HOME Study, a prospective birth cohort Cincinnati, OH (n = 370). estimated elemental carbon...
To evaluate the cost effectiveness of various preeclampsia screening and aspirin prophylaxis strategies, including a strategy based on biomarker ultrasound measures.We designed decision analysis to compare preeclampsia-related costs effects four strategies for use in pregnancy initiated before 16 weeks gestation prevent preeclampsia. The were: 1) no use, 2) measure-predicated 3) U.S. Preventive Services Task Force guidelines, 4) universal use. Our outcomes were number cases per 100,000...
To compare neonatal neurologic complication rates of cesarean deliveries, forceps-assisted vaginal and vacuum-assisted deliveries.Data on singleton live births at 34 weeks or greater gestation born to nulliparous women from 1995 2003 in New York City were linked hospital discharge data. Any diagnosis subdural hemorrhage, intraventricular seizures, scalp laceration cephalohematoma, fracture, facial nerve palsy, brachial plexus injury, 5-minute Apgar score less than 7 was considered...
In Brief OBJECTIVE: To estimate whether blood-contaminated amniotic fluid affects the performance of white blood cell (WBC) count in diagnosing intraamniotic inflammation and infection. METHODS: Three hundred fifty-seven consecutive women pregnant with singletons undergoing amniocentesis to rule out infection were enrolled prospectively. A “bloody tap” was defined as a red (RBC) 1,000 cells/mm3 or more. Proteomics analysis used this study standard for inflammation. Infection confirmed by...
Problem Diabetes confers an increased risk of preeclampsia, but its pathogenic role in preeclampsia is poorly understood. The objective this study was to elucidate the effects excess glucose on trophoblast function and whether any changes could be reversed by metformin. Method human first trimester cell line (Sw.71) treated with at 5, 10, 25, 50 m , presence absence Trophoblast migration quantified supernatant cytokine, chemokine, angiogenic factors measured. Results Increasing...
The provision of antenatal corticosteroids to pregnant patients at gestational age (GA) 22 6/7 weeks or less remains controversial and lacks support from randomized clinical trials.
Gestational diabetes mellitus (GDM) has been rising in the United States, and it poses significant health risks to pregnant individuals their infants. Prior research shown that with GDM also experience prevalent stress mental issues, which can further contribute glucose regulation difficulties. Stigma associated may these challenges, yet there is a lack of focused on GDM-related stigma, its impact psychological health, effective coping mechanisms. Thus, this qualitative study aims understand...
Importance When preterm delivery is imminent, it remains unclear whether the timing from administration of antenatal betamethasone to birth may reduce mortality and morbidity among extremely infants. Objective To evaluate association duration exposure first dose with outcomes Design, Setting, Participants This cohort study enrolled infants born at 22 0/7 27 6/7 weeks’ gestation January 2016 February 2021 National Institute Child Health Human Development Neonatal Research Network centers....
To examine the association between route of delivery and neonatal outcomes in a large, diverse cohort preterm, appropriate-for-gestational-age neonates. This is retrospective study examining New York City birth data for 1995-2003 linked to hospital discharge data. Data were limited singleton, live-born, cephalic neonates delivered 24 34 weeks gestation. Exclusion criteria included congenital anomalies, forceps or vacuum assistance, weight missing, less than 500 g, not appropriate gestational...
<b>Objective</b> Given that most women with gestational diabetes mellitus (GDM) never undergo the recommended 6 to 12 weeks postpartum glucose tolerance test (GTT), we assessed feasibility of performing GTTs on day 2. <b>Study Design</b> We conducted a prospective cohort study in which GDM received 75-g 2-hour GTT this and compared results standard care at postpartum. also evaluated maternal pregnancy characteristics who return for those lost follow-up. <b>Results</b> In study, 98 106...