Angelita M. Hensman
A5016662283- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Infant Nutrition and Health
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Birth, Development, and Health
- Breastfeeding Practices and Influences
- Neonatal Health and Biochemistry
- Respiratory Support and Mechanisms
- Child Nutrition and Feeding Issues
- Cardiac Arrest and Resuscitation
- Neonatal and Maternal Infections
- Metabolism and Genetic Disorders
- Ethics and Legal Issues in Pediatric Healthcare
- Infectious Encephalopathies and Encephalitis
- Cardiovascular Conditions and Treatments
- Child Development and Digital Technology
- Hemoglobinopathies and Related Disorders
- Non-Invasive Vital Sign Monitoring
- Maternal Mental Health During Pregnancy and Postpartum
- Energy Harvesting in Wireless Networks
- Preterm Birth and Chorioamnionitis
- Iron Metabolism and Disorders
- Anesthesia and Neurotoxicity Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2021-2025
Research Network (United States)
2021-2025
Health and Human Development (2HD) Research Network
2023-2025
Women & Infants Hospital of Rhode Island
2003-2024
Brown University
2004-2024
Clinical Trial Investigators
2024
University of Rhode Island
2017-2020
Providence College
2003-2020
Rainbow Babies & Children's Hospital
2018
Children's Mercy Hospital
2018
Objective. Bronchopulmonary dysplasia (BPD) is the endpoint of many intervention trials in neonatology, yet outcome measure when based solely on oxygen administration may be confounded by differing criteria for between physicians. We previously reported a technique to standardize definition BPD sites using timed room-air challenge selected infants. hypothesized that physiologic would reduce variation observed rates among different neonatal centers. Methodology. A total 1598 consecutive...
Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately neonatal mortality and childhood morbidity. To review survival, in-hospital morbidities, care practices, neurodevelopmental functional outcomes at 22-26 months' corrected age for infants. Prospective registry born 19 US academic centers that are part of the Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network. The study included 10 877...
<h3>Importance</h3> Hypothermia initiated at less than 6 hours after birth reduces death or disability for infants with hypoxic-ischemic encephalopathy 36 weeks' later gestation. To our knowledge, hypothermia trials have not been performed in presenting hours. <h3>Objective</h3> estimate the probability that to 24 risk of 18 months among encephalopathy. <h3>Design, Setting, and Participants</h3> A randomized clinical trial was conducted between April 2008 June 2016 gestation moderate severe...
Importance Maternal milk feeding of extremely preterm infants during the birth hospitalization has been associated with better neurodevelopmental outcomes compared formula. For receiving no or minimal maternal milk, it is unknown whether donor human conveys similar advantages vs Objective To determine if nutrient-fortified, pasteurized improves at 22 to 26 months’ corrected age infant formula among who received milk. Design, Setting, and Participants Double-blind, randomized clinical trial...
Premature infants are at high risk of early-onset sepsis (EOS) relative to term infants, and most administered empirical antibiotics after birth. We aimed determine if factors evident birth could be used identify premature lower EOS.Study were born 22 28 weeks' gestation in Neonatal Research Network centers from 2006 2014. EOS was defined by isolation pathogenic species blood or cerebrospinal fluid culture ≤72 hours age. Infants hypothesized as "low risk" for when delivered via cesarean...
Importance Meta-analyses suggest that corticosteroids may be associated with increased survival without cerebral palsy in infants at high risk of bronchopulmonary dysplasia (BPD) but are adverse neurologic outcomes low-risk infants. Whether this association exists contemporary practice is uncertain because most randomized clinical trials administered earlier and higher doses than currently recommended. Objective To evaluate whether the pretreatment death or grade 2 3 BPD 36 weeks’...
BACKGROUND AND OBJECTIVE: The Surfactant Positive Airway Pressure and Pulse Oximetry Randomized Trial (SUPPORT) antenatal consent study demonstrated that mothers of infants enrolled in the SUPPORT trial had significantly different demographics exposure to steroids compared with eligible, but not infants. objective this analysis was compare outcomes bronchopulmonary dysplasia, severe retinopathy prematurity, intraventricular hemorrhage or periventricular leukomalacia (IVH/PVL), death,...
The purposes of this study were to quantify the time and effort involved in obtaining prenatal consent for Neonatal Research Network Surfactant Positive Airway Pressure Pulse Oximetry Randomized Trial (SUPPORT) determine whether enrolled infants representative eligible population. Eligible subjects likely deliver SUPPORT gestational age window (24-27(6/7)] weeks). Data included who approached consent, how often they approached, duration each contact, was obtained, trial. Eligible,...
<h3>Importance</h3> Both preterm birth and increased screen time are known to be associated with an increase in risk of developmental behavioral sequelae. The association between high or a television computer the bedroom early school age adverse cognitive, executive function, language, behavior outcomes extremely children (EPT) is not well understood. <h3>Objective</h3> To assess cognition, EPT aged 6 7 years; second objective was examine rates structured physical activity weight....
The provision of antenatal corticosteroids to pregnant patients at gestational age (GA) 22 6/7 weeks or less remains controversial and lacks support from randomized clinical trials.
Importance Observational studies often report that anemia and red blood cell (RBC) transfusions are associated with a higher risk of necrotizing enterocolitis (NEC) among extremely low-birthweight (ELBW) infants. Objective To evaluate whether there is temporal association between 72-hour hazard periods exposure to RBC NEC ELBW infants randomized either or lower hemoglobin transfusion thresholds. Design, Setting, Participants This post hoc secondary analysis 1690 who survived postnatal day 10...
Importance The neonatal brain injury score on magnetic resonance imaging following moderate or severe hypoxic-ischemic encephalopathy developed by the National Institute of Child Health and Human Development Neonatal Research Network has been revised to separate watershed basal ganglia thalamic their associated outcomes. Objective To evaluate association with outcomes death disability among all infants, neurodevelopment survivors in a trial deeper longer cooling. Design, Setting,...
Importance When preterm delivery is imminent, it remains unclear whether the timing from administration of antenatal betamethasone to birth may reduce mortality and morbidity among extremely infants. Objective To evaluate association duration exposure first dose with outcomes Design, Setting, Participants This cohort study enrolled infants born at 22 0/7 27 6/7 weeks’ gestation January 2016 February 2021 National Institute Child Health Human Development Neonatal Research Network centers....
Importance Hypothermia begun less than 6 hours after birth reduces death or disability in infants with encephalopathy due to hypoxia-ischemia at 36 more weeks’ gestation. Trials of hypothermia for younger gestation are lacking. Objective To assess the probability that decreases 33 35 moderate severe hypoxic-ischemic encephalopathy. Design, Setting, and Participants This randomized clinical trial was conducted between July 2015 December 2022 birth. Bayesian intention-to-treat analyses were...
Little is known about how very low birth weight (VLBW) affects survival and morbidities among infants with trisomy 13 (T13) or 18 (T18). We examined the care plans for VLBW T13 T18 compared their risks of mortality neonatal 21 without defects.Infants 401 to 1500 g born cared at a participating center Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network during period 1994-2009 were studied. Poisson regression models used examine risk death T18.Of...