- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Congenital Heart Disease Studies
- Pediatric Pain Management Techniques
- Neuroscience of respiration and sleep
- Neonatal skin health care
- Neonatal and Maternal Infections
- Anesthesia and Neurotoxicity Research
- Anesthesia and Pain Management
- Respiratory Support and Mechanisms
- Neonatal Health and Biochemistry
- Family and Patient Care in Intensive Care Units
- Cardiovascular Conditions and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Healthcare Systems and Technology
- Heterotopic Ossification and Related Conditions
- Cardiac Arrest and Resuscitation
- Trauma Management and Diagnosis
- Advanced MRI Techniques and Applications
- Hypertrophic osteoarthropathy and related conditions
- Neurogenetic and Muscular Disorders Research
Nationwide Children's Hospital
2016-2025
The Ohio State University
2014-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2021-2025
Research Network (United States)
2021-2025
The Ohio State University Wexner Medical Center
2018-2024
Wayne State University
2016
Children's Hospital of Michigan
2011-2013
Beaumont Hospital, Royal Oak
2007
Importance Hypothermia begun less than 6 hours after birth reduces death or disability in infants with encephalopathy due to hypoxia-ischemia at 36 more weeks’ gestation. Trials of hypothermia for younger gestation are lacking. Objective To assess the probability that decreases 33 35 moderate severe hypoxic-ischemic encephalopathy. Design, Setting, and Participants This randomized clinical trial was conducted between July 2015 December 2022 birth. Bayesian intention-to-treat analyses were...
OBJECTIVES This quality improvement initiative aimed to decrease unrelieved postoperative pain and improve family satisfaction with management. METHODS NICUs within the Children’s Hospitals Neonatal Consortium that care for infants complex surgical problems participated in this collaborative. Each of these centers formed multidisciplinary teams develop aims, interventions, measurement strategies test multiple Plan-Do-Study-Act cycles. Centers were encouraged adopt evidence-based...
To compare the neurodevelopmental outcomes at 18-22 months' corrected age of extremely premature infants exposed to a complete course, an incomplete course or no dose antenatal steroids (ANS).Retrospective chart review (<28 weeks gestational age) neonates over 3-year period. Neurodevelopmental assessment included standardized neurologic examination and Bayley Scales Infant Toddler development II III. Intact survival was defined as without cerebral palsy (CP), blindness deafness mental...
Delays with enteral and oral feeding milestones among premature infants bronchopulmonary dysplasia (BPD) can be due to provider variation or infant-dependent factors. Our objectives this study were compare aerodigestive length of stay in BPD after implementing a quality improvement program improve outcomes.Using the Institute for Healthcare Improvement model improvement, we implemented simplified, individualized, milestone-targeted, pragmatic, longitudinal, educational (SIMPLE) strategy...
The Apgar score has been shown to have utility in predicting mortality the extremely preterm infant delivery hospital populations, where most occurs within 12 hours of birth. We tested hypothesis that 5 minute would remain associated with infants after transfer from an all referral neonatal intensive care unit at average age 10 days.A retrospective analysis 454 born < 27 weeks gestation.The median was 3 1 (interquartile range [IQR] 2-6) and 6 minutes (IQR 4-7). increased by 2.0 ± 1.7 (p...
To evaluate readmission data in a level IV neonatal intensive care unit (NICU) to identify patient characteristics and process failures which serve as drivers for readmission.Our center is primary referral Central Southeast Ohio, providing us unique opportunity readmissions. We studied our current discharge process, caregiver perception of readiness, parental comfort the pre-discharge post-discharge infants.Our rate during 4 year period has remained stable at 9.8%. 74% caregivers rated that...
OBJECTIVES: We pursued the use of regional analgesia (RA) to minimize postoperative opioids. Our aim was increase RA for eligible surgical procedures in NICU from 0% 80% by June 30, 2019. METHODS: A multidisciplinary team determined eligibility criteria, developed an extensive process map, implemented comprehensive education, and a structured communication pain management plans. Daily rounds provided opportunity collaborative comanagement. An additional 30 minutes catheter placement added...
To determine whether a decrease in patent ductus arteriosus (PDA) treatment or ligation extremely preterm (EP) infants was associated with changes rates of mortality and/or morbidities.Observational study on EP admitted from 2008 to 2015. The small baby guidelines do not mandate ligation, however, late 2010 the were amended based new literature suggested that may increase morbidities.There 717 during period. There no significant gestational age, birthweight annual admissions rate PDA medical...
As survival has improved in the Neonatal Intensive Care Unit (NICU), there been a 10-fold increase proportion of infants requiring tracheostomy. At our institution, we observed wide variation duration opioid use posttracheostomy from 6 to 148 days. We aimed decrease exposure postoperative tracheostomy patients NICU baseline average 24 days 7 by December 31, 2017.We established multidisciplinary team develop change ideas implement 3 Plan-Do-Study-Act cycles that focused on enhanced care plan...
Abstract Objective: This is a comprehensive study designed to evaluate the clinical usefulness of transcutaneous bilirubinometry (TcB) in very low birth weight (VLBW) newborns African American (AA) descent. Methods: TcB was conducted at anterior superior iliac spine (ASIS), temporal region and sternum within 2 h total serum bilirubin (TSB) measurements born ≤32 weeks’ gestation prospectively. Average (AVG) levels were also calculated. The relationships between TSB analyzed using...
We delineate the natural history of a right-to-left or bidirectional (RL/BD) patent ductus arteriosus (PDA) in preterm infants and compare outcomes an RL/BD left-to-right (LR) ductal shunt. performed retrospective chart review (<32 weeks), who, between 2 30 days age, had PDA >1.5 mm (study group; n = 74) LR (n 87) on echocardiogram (ECHO). In study group, 27% who were significantly lower gestational age birth weight “prolonged” two more ECHOs. Infants with required greater surfactant (98.6%...
Routine blood gas measurements are common in infants with severe bronchopulmonary dysplasia (sBPD) and a noxious stimulus. We developed guideline-driven approach to evaluate the care of sBPD without routine sampling chronic phase NICU (after diagnosis at 36 weeks PMA).